Articles with "mir 320a" as a keyword



MicroRNA‐320a inhibits invasion and metastasis in osteosarcoma by targeting cytoplasmic polyadenylation element‐binding protein 1

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Published in 2020 at "Cancer Medicine"

DOI: 10.1002/cam4.2919

Abstract: Osteosarcoma is a primary malignant bone tumor, which affects children, adolescents, and young adults commonly. MicroRNAs (miRNAs) have been proved to be dysregulated in different cancers, including osteosarcoma. Although miR‐320a has been implicated in many… read more here.

Keywords: cytoplasmic polyadenylation; polyadenylation element; osteosarcoma; binding protein ... See more keywords
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Novel insights into role of miR‐320a‐VDAC1 axis in astrocyte‐mediated neuronal damage in neuroAIDS

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Published in 2017 at "Glia"

DOI: 10.1002/glia.23089

Abstract: Astroglia are indispensable component of the tripartite synapse ensheathing innumerous soma and synapses. Its proximity to neurons aids the regulation of neuronal functions, health and survival through dynamic neuroglia crosstalk. Susceptibility of astrocyte to HIV‐1… read more here.

Keywords: hiv; vdac1; hiv tat; atp release ... See more keywords

Deregulation of RUNX2 by miR-320a deficiency impairs steroidogenesis in cumulus granulosa cells from polycystic ovary syndrome (PCOS) patients.

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Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2016.12.059

Abstract: Deregulation of epigenetic modification by microRNAs (miRNAs) contributes to the development of estrogen deficiency, a hallmark of the multigenic endocrine disorder polycystic ovary syndrome (PCOS), but its etiology remains unclear. Previous study has pointed to… read more here.

Keywords: ccs; pcos; expression; deregulation ... See more keywords

LncRNA MALAT1 aggravates the retinal angiogenesis via miR-320a/HIF-1α axis in diabetic retinopathy.

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Published in 2022 at "Experimental eye research"

DOI: 10.1016/j.exer.2022.108984

Abstract: Diabetic retinopathy (DR) is one of the most serious microvascular complications of diabetes and an important cause of blindness in adults. In previous study, we found that miR-320a alleviated the damage of muller cells in… read more here.

Keywords: hif; angiogenesis; mir 320a; lncrna malat1 ... See more keywords

MiR-320a-3p/ELF3 axis regulates cell metastasis and invasion in non-small cell lung cancer via PI3K/Akt pathway.

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Published in 2018 at "Gene"

DOI: 10.1016/j.gene.2018.05.100

Abstract: MicroRNAs (miRNAs) play important roles in tumorigenesis and tumor progression. In this study, we investigated the role of miR-320a-3p in non-small cell lung cancer (NSCLC). Expressions of miR-320a-3p were firstly determined in 80 NSCLC patients'… read more here.

Keywords: invasion; non small; cancer; cell ... See more keywords

miR-320a Targeting RGS5 Aggravates Atherosclerosis by Promoting Migration and Proliferation of ox-LDL–Stimulated Vascular Smooth Muscle Cells

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Published in 2022 at "Journal of Cardiovascular Pharmacology"

DOI: 10.1097/fjc.0000000000001286

Abstract: Supplemental Digital Content is Available in the Text. Abstract: MicroRNAs have been implicated in atherosclerosis (AS) progression. Here, we focused on how miR-320a affect AS progression via vascular smooth muscle cells (VSMCs). Oxidized low-density lipoproteins… read more here.

Keywords: rgs5; proliferation; expression; mir 320a ... See more keywords

Astragaloside IV inhibits angiotensin II-induced aortic dissection formation by regulating miR-320a/matrix metallopeptidase 9 axis

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Published in 2023 at "Materials Express"

DOI: 10.1166/mex.2023.2367

Abstract: This study explored the role of miR-320a and Matrix metallopeptidase 9 (MMP-9) in aortic dissection (AD) formation. Aortic tissue diameter (LD) and medial thickness (MT) were measured after the AD model was established. Aortic smooth… read more here.

Keywords: group; mir 320a; angii group; mmp9 ... See more keywords

A nanodrug system overexpressed circRNA_0001805 alleviates nonalcoholic fatty liver disease via miR-106a-5p/miR-320a and ABCA1/CPT1 axis

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Published in 2021 at "Journal of Nanobiotechnology"

DOI: 10.1186/s12951-021-01108-8

Abstract: Our study aimed to explore the function of circRNA_0001805 in the pathogenesis of NAFLD and the underlying mechanism. A nanodrug system (GA-RM/GZ/PL) was constructed to overexpress circRNA_0001805 specifically in hepatocytes for the treatment of NAFLD.… read more here.

Keywords: 106a mir; mir; circrna 0001805; abca1 cpt1 ... See more keywords

METTL3 accelerates staphylococcal protein A (SpA)-induced osteomyelitis progression by regulating m6A methylation-modified miR-320a

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Published in 2024 at "Journal of Orthopaedic Surgery and Research"

DOI: 10.1186/s13018-024-05164-2

Abstract: Osteomyelitis (OM) is an inflammatory disease of bone infection and destruction characterized by dysregulation of bone homeostasis. Staphylococcus aureus (SA) has been reported to be the most common pathogen causing infectious OM. Recent studies have… read more here.

Keywords: osteogenic differentiation; spa; oxidative stress; mir 320a ... See more keywords

The role of lncRNA TSIX in osteoarthritis pathogenesis: mechanistic insights and clinical biomarker potential

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Published in 2024 at "Journal of Orthopaedic Surgery and Research"

DOI: 10.1186/s13018-024-05207-8

Abstract: This study seeks to elucidate the expressions of lncRNA TSIX in Osteoarthritis (OA) and to explore its mechanisms in regulating OA progression. RT-qPCR was employed to analyze the expression of TSIX in OA patients classified… read more here.

Keywords: mir 320a; tsix; expression; tsix osteoarthritis ... See more keywords
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Human Glucagon Expression Is under the Control of miR-320a.

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Published in 2021 at "Endocrinology"

DOI: 10.1210/endocr/bqaa238

Abstract: Increased glucagon is a hallmark of diabetes and leads to worsening of the hyperglycemia, but the molecular mechanisms causing it are still unknown. We therefore investigated the possibility that microRNAs might be involved in the… read more here.

Keywords: glucagon expression; glucagon; mir 320a; expression control ... See more keywords