Articles with "mir 331" as a keyword



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A comprehensive clinicopathological evaluation of the differential expression of microRNA-331 in breast tumors and its diagnostic significance.

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Published in 2018 at "Clinical biochemistry"

DOI: 10.1016/j.clinbiochem.2018.07.008

Abstract: OBJECTIVE MicroRNA-331 (miR-331) has shown regulatory activity against several genes whose expression has been claimed to be deregulated in breast tumors, including that of epidermal growth factor receptor 2 (HER2). Herein, the clinical value of… read more here.

Keywords: mir 331; breast; breast tumors; value ... See more keywords
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Circ_0062270 upregulates EPHA2 to facilitate melanoma progression via sponging miR-331-3p.

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Published in 2021 at "Journal of dermatological science"

DOI: 10.1016/j.jdermsci.2021.08.005

Abstract: BACKGROUND Circular RNA (circRNA) has been confirmed to play a vital role in melanoma progression. OBJECTIVE The regulatory function of circ_0062270, a novel circRNA, in melanoma progression is unclear. METHODS Relative expression levels of circ_0062270… read more here.

Keywords: circ 0062270; melanoma progression; melanoma; mir 331 ... See more keywords
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Circular RNA circPSAP functions as an efficient miR-331-3p sponge to regulate proliferation, apoptosis and bortezomib sensitivity of human multiple myeloma cells by upregulating HDAC4.

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Published in 2022 at "Journal of pharmacological sciences"

DOI: 10.1016/j.jphs.2022.01.013

Abstract: BACKGROUND Multiple myeloma (MM) is a malignant tumor of plasma cells in the bone marrow. Circular RNAs (circRNAs) exert important activity in the tumorigenesis and chemoresistance of MM. In the current work, we sought to… read more here.

Keywords: mir 331; apoptosis; proliferation; cell ... See more keywords
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Gastrodin combined with rhynchophylline inhibits cerebral ischaemia-induced inflammasome activation via upregulating miR-21-5p and miR-331-5p.

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Published in 2019 at "Life sciences"

DOI: 10.1016/j.lfs.2019.116935

Abstract: BACKGROUND The protective effects of gastrodin and rhynchophylline in ischaemic injury have been reported. However, the underlying mechanism and the effect of the combination of these two drugs in ischaemic injury remain unclear. Herein, we… read more here.

Keywords: gastrodin rhynchophylline; mir 331; inflammasome activation; mir mir ... See more keywords
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microRNA-331-3p maintains the contractile type of vascular smooth muscle cells by regulating TNF-α and CD14 in intracranial aneurysm

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Published in 2020 at "Neuropharmacology"

DOI: 10.1016/j.neuropharm.2019.107858

Abstract: Dysfunction of vascular smooth muscle cells (VSMCs) may be linked to intracranial aneurysm (IA) formation. VSMCs possess a phenotypic plasticity, capable of changing from a mature, contractile to a less differentiated, synthetic phenotype. In this… read more here.

Keywords: aneurysm; mir 331; tnf cd14; cd14 ... See more keywords
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MicroRNA miR-331-3p suppresses osteosarcoma progression via the Bcl-2/Bax and Wnt/β-Catenin signaling pathways and the epithelial-mesenchymal transition by targeting N-acetylglucosaminyltransferase I (MGAT1)

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2083855

Abstract: ABSTRACT Osteosarcoma (OS) is a high-grade malignant disease that is a prevalent primary malignant sarcoma of the bone. The purpose of this investigation was to therefore elucidate the association between miR-331-3p and OS development and… read more here.

Keywords: mgat1; wnt catenin; mir 331; bcl bax ... See more keywords
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CircRNA High Mobility Group At-hook 2 regulates cell proliferation, metastasis and glycolytic metabolism of nonsmall cell lung cancer by targeting miR-331-3p to upregulate High Mobility Group At-hook 2

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Published in 2022 at "Anti-Cancer Drugs"

DOI: 10.1097/cad.0000000000001343

Abstract: Increasing circular RNAs (circRNAs) have been identified as pivotal players in nonsmall cell lung cancer (NSCLC). The study will explore the function and mechanism of circRNA High Mobility Group AT-hook 2 (circHMGA2) in NSCLC. The… read more here.

Keywords: group hook; cell; mir 331; mobility group ... See more keywords
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Overexpression of miR-331 Indicates Poor Prognosis and Promotes Progression of Breast Cancer

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Published in 2020 at "Oncology Research and Treatment"

DOI: 10.1159/000508792

Abstract: Background: With the increasing number of cases of breast cancer every year, the exploration of novel biomarkers has drawn attention. miR-331 has been demonstrated to play a role in various cancers, but its role in… read more here.

Keywords: overexpression mir; mir 331; prognosis; breast cancer ... See more keywords
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LncRNA UCA1 Accelerates the Progression of Ulcerative Colitis via Mediating the miR-331-3p/BRD4 Axis

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Published in 2021 at "International Journal of General Medicine"

DOI: 10.2147/ijgm.s304837

Abstract: Background Ulcerative colitis (UC) has become one of the fastest-growing severe diseases worldwide with high morbidity. This research aimed to explore the function of lncRNA UCA1 in UC progression. Methods RT-qPCR analysis was used to… read more here.

Keywords: mir 331; ulcerative colitis; 331 brd4; lncrna uca1 ... See more keywords
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LncRNA XLOC_006390 facilitates cervical cancer tumorigenesis and metastasis as a ceRNA against miR-331-3p and miR-338-3p

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Published in 2018 at "Journal of Gynecologic Oncology"

DOI: 10.3802/jgo.2018.29.e95

Abstract: Objective Cervical cancer is one of the most common malignant tumors. Our previous results showed that long non-coding RNA (lncRNA) XLOC_006390 plays an important role in cervical cancer. In this study, we have explored the… read more here.

Keywords: mir 331; mir; cervical cancer; mir 338 ... See more keywords
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LncRNA AC005332.7 Inhibited Ferroptosis to Alleviate Acute Myocardial Infarction Through Regulating miR-331-3p/CCND2 Axis

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Published in 2023 at "Korean Circulation Journal"

DOI: 10.4070/kcj.2022.0242

Abstract: Author's summary AC005332.7 overexpression alleviated myocardial injury via suppressing ferroptosis in vitro and in vivo. AC005332.7 could directly bind to miR-331-3p to promote cyclin D2 (CCND2) expression. MiR-331-3p sufficiency or CCND2 knockdown reversed AC005332.7-mediated inhibition… read more here.

Keywords: mir 331; ac005332; ccnd2; myocardial infarction ... See more keywords