Circular RNA MAT2B Promotes Glycolysis and Malignancy of Hepatocellular Carcinoma Through the miR‐338‐3p/PKM2 Axis Under Hypoxic Stress
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30671
Abstract: Glucose metabolism reprogramming, which is a well‐established characteristic of multiple cancers, demands a higher rate of glycolysis to meet the increasing demands for macromolecular synthesis and to maintain rapid proliferation in a hypoxic environment. However,… read more here.
Keywords: hcc; glycolysis; circmat2b; rna ... See more keywords
MiR‐338‐5p Promotes Inflammatory Response of Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis via Targeting SPRY1
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25883
Abstract: Our purpose is to study the roles of microRNA‐338‐5p (miR‐338‐5p) on the proliferation, invasion, and inflammatory response of fibroblast‐like synoviocytes (SFs) in rheumatoid arthritis patients by regulating SPRY1. The target relationship between miR‐338‐5p and SPRY1… read more here.
Keywords: inflammatory response; proliferation; expression; rheumatoid arthritis ... See more keywords
GATA1 activated lncRNA (Galont) promotes anoxia/reoxygenation‐induced autophagy and cell death in cardiomyocytes by sponging miR‐338
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26623
Abstract: The hypernomic autophagy is associated with various cardiovascular diseases. Long noncoding RNAs (lncRNAs) are emerging as important regulators in gene expression, which have been involved in multiple physiological and pathological processes. However, the function of… read more here.
Keywords: mir 338; activated lncrna; gata1 activated; cell death ... See more keywords
MiR‐338 regulates NFATc1 expression and inhibits the proliferation and epithelial‐mesenchymal transition of human non‐small‐cell lung cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1091
Abstract: It is well known that nuclear factor of activated T cells c1 (NFATc1) expression is closely associated with progression of many cancers. And we found that miR‐338 could directly target the NFATc1. However, the precise… read more here.
Keywords: lung cancer; cell lung; nfatc1 expression; non small ... See more keywords
MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to FOXD1
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-018-2745-y
Abstract: PurposeMicroRNAs (miRs) play an important role in many cancers and can affect cancer cell behavior, including glioma. This study aims at investigating the effects of miR-338-5p on the senescence, migration, invasion, and apoptosis of glioma… read more here.
Keywords: glioma; signaling pathway; mapk signaling; expression ... See more keywords
Promotive Role of CircATRNL1 on Chondrogenic Differentiation of BMSCs mediated by miR-338-3p.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of medical research"
DOI: 10.1016/j.arcmed.2021.02.003
Abstract: AIM Bone marrow mesenchymal stem cells (BMSCs) are ideal seed cells for tissue engineering cartilage construction. However, the underlying mechanism of it has not been illuminate well. In this study, the effects of circATRNL1 (hsa_circ_0020093)… read more here.
Keywords: differentiation bmscs; chondrogenic differentiation; differentiation; mir 338 ... See more keywords
LncRNA SNHG1 alleviates OGD induced injury in BMEC via miR-338/HIF-1α axis
Sign Up to like & getrecommendations! Published in 2019 at "Brain Research"
DOI: 10.1016/j.brainres.2018.11.003
Abstract: BACKGROUND Brain microvascular endothelial cell (BMEC) is an important therapeutic target for the inhibition of brain vascular dysfunction in ischemic stroke. Expression of long non-coding RNA SNHG1 is reportedly upregulated in BMEC after OGD. The… read more here.
Keywords: snhg1; ogd induced; bmec; induced injury ... See more keywords
LINC00943 acts as miR-338-3p sponge to promote MPP+-induced SK-N-SH cell injury by directly targeting SP1 in Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Brain Research"
DOI: 10.1016/j.brainres.2022.147814
Abstract: BACKGROUND Abnormal expression of long non-coding RNA (lncRNA) is associated with the progression of Parkinson's disease (PD). LINC00943 has been proved to play an important role in the development of PD, so its role and… read more here.
Keywords: cell injury; sp1; mpp; mir 338 ... See more keywords
miR-219 Cooperates with miR-338 in Myelination and Promotes Myelin Repair in the CNS.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental cell"
DOI: 10.1016/j.devcel.2017.03.001
Abstract: A lack of sufficient oligodendrocyte myelination contributes to remyelination failure in demyelinating disorders. miRNAs have been implicated in oligodendrogenesis; however, their functions in myelin regeneration remained elusive. Through developmentally regulated targeted mutagenesis, we demonstrate that… read more here.
Keywords: myelin repair; myelination; cns; mir 338 ... See more keywords
MiR-338-5p promotes metastasis of colorectal cancer by inhibition of phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated autophagy pathway
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.04.010
Abstract: Background In our preliminary screening, expression of miR-338-5p was found to be higher in primary colorectal cancer (CRC) with metastasis. The autophagy related gene- phosphatidylinositol 3-kinase, catalytic subunit type 3 (PIK3C3) appeared to be targeted… read more here.
Keywords: colorectal cancer; metastasis; phosphatidylinositol kinase; pik3c3 ... See more keywords
A potential therapeutic target for regulating osteoporosis via suppression of osteoclast differentiation.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of dentistry"
DOI: 10.1016/j.jdent.2019.01.015
Abstract: OBJECTIVES Osteoclast differentiation is regulated by transcriptional, post-transcriptional and post-translational mechanisms. Micro-ribonucleic acids (miRNAs) are 20-24 nucleotides long non-coding RNAs involved in post-translational regulation of gene expressions during osteoclast differentiation. The objective of the present… read more here.
Keywords: osteoclast differentiation; differentiation; mir 338; raw264 cells ... See more keywords