miR-33a inhibits cell proliferation and invasion by targeting CAND1 in lung cancer
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-017-1730-2
Abstract: BackgroundLung cancer continues to be one of the top five causes of cancer-related mortality. This study aims to identify down- and upregulated miRNAs and mRNA which can be used as potential biomarkers and/or therapeutic targets… read more here.
Keywords: proliferation; mir 33a; lung cancer; cancer ... See more keywords
B-RCA revealed circulating miR-33a/b associates with serum cholesterol in type 2 diabetes patients at high risk of ASCVD.
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2018.03.024
Abstract: AIMS Type 2 diabetes (T2D) is a complex metabolic disease with high incidence throughout the world. Dyslipidemia is the leading cause of atherosclerotic cardiovascular diseases (ASCVD) in T2D patients. hsa-miR-33 (miR-33) serves as a regulator… read more here.
Keywords: high risk; circulating mir; cholesterol; mir 33a ... See more keywords
MiR-33a is a therapeutic target in SPG4-related hereditary spastic paraplegia human neurons.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical science"
DOI: 10.1042/cs20180980
Abstract: Recent reports, including ours, have indicated that microRNA (miR)-33 located within the intron of sterol regulatory element binding protein (SREBP) 2 controls cholesterol homeostasis and can be a potential therapeutic target for the treatment of… read more here.
Keywords: hereditary spastic; therapeutic target; human neurons; mir 33a ... See more keywords
Molecular mechanisms in the miR-33a/LPPR4 pathway regulating unsaturated fatty acid synthesis in bovine mammary epithelial cells.
Sign Up to like & getrecommendations! Published in 2022 at "Animal biotechnology"
DOI: 10.1080/10495398.2022.2111308
Abstract: The regulatory mechanisms governing metabolism of fatty acids in cow mammary gland are crucial for establishing relationships between milk quality and fatty acid content. Both, microRNAs (miRNAs) and protein-coding genes are important factors involved in… read more here.
Keywords: mir 33a; synthesis; unsaturated fatty; lppr4 pathway ... See more keywords
Can circulating miR-7-1-5p, and miR-33a-5p be used as markers of T2D patients?
Sign Up to like & getrecommendations! Published in 2021 at "Archives of physiology and biochemistry"
DOI: 10.1080/13813455.2021.1871762
Abstract: PURPOSE Recent evidence has indicated that miRNAs play an important role in both initiation and progression of many pathologic processes such as diabetes and can be used as an important and more sensitive tool to… read more here.
Keywords: t2d patients; mir mir; mir; expression ... See more keywords
Long non-coding RNA tumor protein 53 target gene 1 promotes cervical cancer development via regulating microRNA-33a-5p to target forkhead box K2
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2026705
Abstract: ABSTRACT Long non-coding RNA tumor protein 53 target gene 1 (TP53TG1) has been unraveled to exert regulatory effects on cancer progression, while the regulatory function of TP53TG1 on cervical cancer (CC) via regulating microRNA (miR)-33a-5p/Forkhead… read more here.
Keywords: via regulating; mir 33a; tp53tg1; foxk2 ... See more keywords
miR-33a-5p Targets RAP2A to Mediate the Sensitivity of Gastric Cancer Cells to 5-FU
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/9701047
Abstract: Objective The objective of this study is to explore the effects of microRNA-33a-5p (miR-33a-5p)-ras-related protein Rap-2a (RAP2A) on biological functions of gastric cancer (GC) and to find the potential functional mechanism. Methods We measured the… read more here.
Keywords: cell; mir 33a; sensitivity; gastric cancer ... See more keywords
Bromodomain and Extra Terminal Domain (BET) Inhibitors Sensitize Chronic Myelomonocytic Leukemia (CMML) to PIM Inhibition Via Downregulation of Mir-33a
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-128165
Abstract: CMML is a lethal myeloid neoplasm with no therapies that improve its dismal prognosis. Inhibition of BET family members has been proposed as a therapeutic strategy based on preclinical data identifying BRD4 as a therapeutic… read more here.
Keywords: pim1; beti; mir 33a; leukemia ... See more keywords
MiR-33a functions as a tumor suppressor in triple-negative breast cancer by targeting EZH2
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Cell International"
DOI: 10.1186/s12935-020-1160-z
Abstract: Background Increasing reports have confirmed that microRNAs play an important role in breast cancer progression, particularly in triple-negative breast cancer (TNBC). The aim of our study was to investigate the role of miR-33a in TNBC… read more here.
Keywords: tnbc; cell; mir 33a; breast cancer ... See more keywords
LncRNA-CASC15 knockdown inhibits the progression of esophageal squamous cell carcinoma through targeting miR-33a-5p/PTGS2 axis.
Sign Up to like & getrecommendations! Published in 2022 at "Histology and histopathology"
DOI: 10.14670/hh-18-517
Abstract: LncRNA CASC15 has been determined as a novel tumor-related lncRNA in many cancers. However, the in-detail role of CASC15 remains elusive in esophageal squamous cell carcinoma (ESCC). CASC15 expression level was detected in 113 ESCC… read more here.
Keywords: casc15; casc15 knockdown; cell; mir 33a ... See more keywords
miR-33a is a tumor suppressor microRNA that is decreased in prostate cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19521
Abstract: Prostate cancer is one of the most frequently diagnosed neoplasms among men worldwide. MicroRNAs (miRNAs) are involved in numerous important cellular processes including proliferation, differentiation and apoptosis. They have been found to be aberrantly expressed… read more here.
Keywords: 33a tumor; prostate cancer; mir 33a;