MicroRNA‐340‐5p increases telomere length by targeting telomere protein POT1 to improve Alzheimer's disease in mice
Sign Up to like & getrecommendations! Published in 2021 at "Cell Biology International"
DOI: 10.1002/cbin.11576
Abstract: Alzheimer′s disease (AD) is a chronic neurodegenerative disorder which is the primary cause of dementia in the elderly. Telomere attrition has been proposed as a hallmark of aging. Our study aimed to explore the mechanism… read more here.
Keywords: alzheimer disease; telomere length; pot1 expression; microrna 340 ... See more keywords
Long noncoding RNA OIP5‐AS1 causes cisplatin resistance in osteosarcoma through inducing the LPAATβ/PI3K/AKT/mTOR signaling pathway by sponging the miR‐340‐5p
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28244
Abstract: The abnormal expression of long noncoding RNAs (lncRNAs) plays an important role in the regulation of human cancer progression and drug resistance. The lncRNA OPI5‐AS1 is a crucial regulator in some cancers; however, its role… read more here.
Keywords: oip5 as1; osteosarcoma; pi3k akt; resistance ... See more keywords
Up-regulation of miR-340-5p promotes progression of thyroid cancer by inhibiting BMP4
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-018-0848-6
Abstract: PurposeThe incidence of thyroid cancer is increasing and the proliferation of thyroid cancer cells is incompletely understood. microRNAs may play key roles in thyroid cancer progression.MethodsWe analyzed miR-340-5p in thyroid cancer tissue and normal tissue,… read more here.
Keywords: thyroid cancer; 340 promotes; bmp4; cancer ... See more keywords
MiR-340 affects gastric cancer cell proliferation, cycle, and apoptosis through regulating SOCS3/JAK-STAT signaling pathway
Sign Up to like & getrecommendations! Published in 2018 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2018.1455208
Abstract: Abstract Objective: Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathway is closely related to tumorigenesis. Suppressors of cytokine signaling 3 (SOCS3) is a negative regulator of JAK-STAT signaling pathway. MiR-340 expression is… read more here.
Keywords: jak; cell proliferation; cycle; cell ... See more keywords
Reduction of lamin B receptor levels by miR-340-5p disrupts chromatin, promotes cell senescence and enhances senolysis.
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic acids research"
DOI: 10.1093/nar/gkab538
Abstract: A major stress response influenced by microRNAs (miRNAs) is senescence, a state of indefinite growth arrest triggered by sublethal cell damage. Here, through bioinformatic analysis and experimental validation, we identified miR-340-5p as a novel miRNA… read more here.
Keywords: lamin receptor; reduction lamin; senescence; senescent ... See more keywords
Sinomenine Inhibits Vasculogenic Mimicry and Migration of Breast Cancer Side Population Cells via Regulating miR-340-5p/SIAH2 Axis
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/4914005
Abstract: Hypoxia and its induced vasculogenic mimicry (VM) formation, which both closely related with stem-like side population (SP) cells, are the main culprits leading to tumor invasion and metastasis. Sinomenine exhibits excellent anticancer activity in breast… read more here.
Keywords: mir 340; breast; breast cancer; sinomenine ... See more keywords
MicroRNA-340 and MicroRNA-450b-5p: Plasma Biomarkers for Detection of Non-Small-Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Environmental and Public Health"
DOI: 10.1155/2022/8024700
Abstract: Objective Since the inefficient cancer management is caused by inaccurate diagnoses, there is a need for minimally invasive method to improve the diagnostic accuracy of non-small-cell lung (NSCLC). This study intended to detect miR-340 and… read more here.
Keywords: plasma mir; nsclc patients; mir 340; mir 450b ... See more keywords
MicroRNA-340-5p modulates cisplatin resistance by targeting LPAATβ in osteosarcoma
Sign Up to like & getrecommendations! Published in 2017 at "Brazilian Journal of Medical and Biological Research"
DOI: 10.1590/1414-431x20176359
Abstract: MicroRNAs (miRNAs) play an important role in drug resistance and modulate the efficiency of chemotherapy. A recent study indicated that miR-340 functions as a tumor suppressor in various types of cancer. However, the role of… read more here.
Keywords: cddp induced; cddp; cell death; lpaat ... See more keywords
Overexpression of microRNA-340-5p Ameliorates Inflammatory Response and Intracellular Survival of Mycobacterium Tuberculosis in Alveolar Type II Cells
Sign Up to like & getrecommendations! Published in 2021 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s291867
Abstract: Background The importance of microRNAs (miRs) has been documented in infections. This study estimated the role of miR-340-5p in Mycobacterium tuberculosis (Mtb)-infected alveolar type II cells. Methods The microarray of GEO database was analyzed to… read more here.
Keywords: mycobacterium tuberculosis; mir 340; infection; mtb infection ... See more keywords
Overexpression of miR-340-5p inhibits skin fibroblast proliferation by targeting Kruppel-like factor 2.
Sign Up to like & getrecommendations! Published in 2019 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201020666190725112304
Abstract: OBJECTIVE MicroRNA (miR)-340-5p has been identified to play a key role in several cancers. However, the function of miR-340-5p in skin fibroblasts remains largely unknown. METHOD Gain of function was used by infecting the normal… read more here.
Keywords: overexpression; ontology; skin fibroblast; fibroblast proliferation ... See more keywords
MicroRNA-340-5p inhibits the malignant phenotypes of osteosarcoma by directly targeting NRF2 and deactivating the PI3K/AKT pathway.
Sign Up to like & getrecommendations! Published in 2021 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202105_25932
Abstract: OBJECTIVE The aim of the study was to examine the effects and potential mechanisms of miR-340-5p in Osteosarcoma (OS) progression. PATIENTS AND METHODS qRT-PCR was applied to detect expressions of miR-340-5p and NRF2 mRNA. MTT… read more here.
Keywords: pi3k akt; targeting nrf2; malignant phenotypes; mir 340 ... See more keywords