miR-34b/c regulates doxorubicin-induced myocardial cell injury through ITCH
Sign Up to like & getrecommendations! Published in 2019 at "Cell Cycle"
DOI: 10.1080/15384101.2019.1673618
Abstract: ABSTRACT Objective: To determine the underlying mechanism of miR-34b/c in regulating doxorubicin (Dox)-induced myocardial cell injury. Methods: The viability of mouse myocardial cells HL-1 was detected by MTT assay. The apoptosis of HL-1 cells was… read more here.
Keywords: itch; mir 34b; induced myocardial; myocardial cell ... See more keywords
Downregulation of lncRNA BACE1-AS improves dopamine-dependent oxidative stress in rats with Parkinson’s disease by upregulating microRNA-34b-5p and downregulating BACE1
Sign Up to like & getrecommendations! Published in 2020 at "Cell Cycle"
DOI: 10.1080/15384101.2020.1749447
Abstract: ABSTRACT Objective: Long noncoding RNAs (lncRNAs) have already been proposed to function in Parkinson’s disease (PD). However, the role of lncRNA BACE1-AS in PD has never been discussed. This study aims to examine the mechanism… read more here.
Keywords: mir 34b; lncrna bace1; substantia nigra; bace1 ... See more keywords
Evaluation of miR-34b/c polymorphisms to the risk of ischemic stroke.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Hypertension"
DOI: 10.1097/hjh.0000000000002413
Abstract: OBJECTIVES Polymorphisms in microRNA genes are related to the risk of ischemic stroke, but the association between miR-34b/c polymorphisms and the risk of ischemic stroke has not been reported. METHODS MiR-34b/c rs2187473 and rs4938723 polymorphisms… read more here.
Keywords: ischemic stroke; rs4938723; risk ischemic; 34b polymorphisms ... See more keywords
MiR‐34b‐3p represses cell proliferation, cell cycle progression and cell apoptosis in non‐small‐cell lung cancer (NSCLC) by targeting CDK4
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.14404
Abstract: Abstract Lung cancer is the most common incident cancer, with a high mortality worldwide, and non‐small‐cell lung cancer (NSCLC) accounts for approximately 85% of cases. Numerous studies have shown that the aberrant expression of microRNAs… read more here.
Keywords: mir 34b; cell; cdk4; lung cancer ... See more keywords
The Rs4938723 Polymorphism Reduces Expression of MicroRNA-34b and Increases the Risk of Recurrence after Endoscopic Dissection in Early Gastric Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000481764
Abstract: Background: In respect to the effect of MET1 upon the recurrence of Early gastric cancer (EGC) after endoscopic dissection (ESD) treatment, we aimed to investigate the molecular mechanism, including the potential regulator and signaling pathways… read more here.
Keywords: mir 34b; recurrence; rs4938723 polymorphism; met1 ... See more keywords
HDL protects against myocardial ischemia reperfusion injury via miR-34b and miR-337 expression which requires STAT3
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0218432
Abstract: Purpose High density lipoprotein (HDL) protects against myocardial infarction via mechanisms that remain unclear. STAT3 (signal transducer and activator of transcription 3) plays a key role in HDL-induced cardioprotection. In the heart, microRNAs (miRNAs) are… read more here.
Keywords: mir 337; mir 34b; 34b mir; hdl ... See more keywords
Berberine Suppresses Mice Depression Behaviors and Promotes Hippocampal Neurons Growth Through Regulating the miR-34b-5p/miR-470-5p/BDNF Axis
Sign Up to like & getrecommendations! Published in 2021 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s289444
Abstract: Background Berberine has been found to inhibit the progression of depression disorder, but its specific mechanism is still unclear. MicroRNA (miRNA) is considered to play an important role in the progression of depression. However, it… read more here.
Keywords: bdnf; mir 34b; berberine; depression ... See more keywords
miR-34b/c-5p/CXCL10 Axis Induced by RSV Infection Mediates a Mechanism of Airway Hyperresponsive Diseases
Sign Up to like & getrecommendations! Published in 2023 at "Biology"
DOI: 10.3390/biology12020317
Abstract: Simple Summary Airway hyperresponsive diseases (AHD), such as asthma and chronic obstructive pulmonary disease (COPD), are a serious public health burden worldwide. Studies have shown that viral infection plays an important role in asthma and… read more here.
Keywords: rsv infection; hyperresponsive diseases; infection; mir 34b ... See more keywords
The Methylation of the p53 Targets the Genes MIR-203, MIR-129-2, MIR-34A and MIR-34B/C in the Tumor Tissue of Diffuse Large B-Cell Lymphoma
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13081401
Abstract: The regulation of oncogenes by microRNA is a focus of medical research. hsa-miR-203, hsa-mir-129, hsa-miR-34a, hsa-miR-34b and hsa-miR-34c are oncosuppressive microRNAs that mediate the antitumor activity of p53. We seek to evaluate the frequencies, co-occurrence… read more here.
Keywords: methylation; mir 203; mir 34b; mir 129 ... See more keywords
Potent Inhibition of miR-34b on Migration and Invasion in Metastatic Prostate Cancer Cells by Regulating the TGF-β Pathway
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18122762
Abstract: The importance of miRNAs in the progression of prostate cancer (PCa) has further been supported by the finding that miRNAs have been identified as potential oncogenes or tumor suppressors in PCa. Indeed, in eukaryotes, miRNAs… read more here.
Keywords: mir 34b; invasion; tgf; expression ... See more keywords
LncRNA RP11-805J14.5 functions as a ceRNA to regulate CCND2 by sponging miR-34b-3p and miR-139-5p in lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Reports"
DOI: 10.3892/or.2022.8376
Abstract: Lung adenocarcinoma (LUAD) is the most common lung cancer with high incidence. The prognosis of LUAD is poor due to its aggressive behavior. Long non-coding RNAs (lncRNAs) have been reported as a key modulator on… read more here.
Keywords: rp11 805j14; luad; mir 139; mir 34b ... See more keywords