Suppression of FoxO1 mRNA by β2‐adrenoceptor–cAMP signaling through miR‐374b‐5p and miR‐7a‐1‐3p in C2C12 myotubes
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DOI: 10.1002/2211-5463.13368
Abstract: β2‐Adrenoceptor (β2‐AR) signaling decreases the transcriptional activity of forkhead box O (FoxO), but the underlying mechanisms remain incompletely understood. Here, we investigated how β2‐AR signaling regulates the protein abundance of FoxO and its transcriptional activity… read more here.
Keywords: foxo1 mrna; camp signaling; mir 374b; 374b mir ... See more keywords
MicroRNA‐374b inhibits cervical cancer cell proliferation and induces apoptosis through the p38/ERK signaling pathway by binding to JAM‐2
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DOI: 10.1002/jcp.26574
Abstract: Cervical cancer (CC) remains a highly prevalent cancer and mortality globally among women globally. The aim of the present study was to assess the ability of miR‐374b to regulate CC cells through JAM‐2, whilst exploring… read more here.
Keywords: mir 374b; jam; signaling pathway; p38 erk ... See more keywords
MAGI2-AS3 and miR-374b-5p as Putative Regulators of Multiple Sclerosis via Modulating the PTEN/AKT/IRF-3/IFN-β Axis: New Clinical Insights.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.2c00653
Abstract: Multiple sclerosis (MS) is a chronic disease and one of the leading causes of disability in young adults. The current study aims to investigate the pathogenesis of MS via studying the regulatory role of novel… read more here.
Keywords: magi2 as3; pten akt; mir 374b; ifn ... See more keywords
Sevoflurane activates MEF2D-mediated Wnt/β-catenin signaling pathway via microRNA-374b-5p to affect renal ischemia/reperfusion injury
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DOI: 10.1080/08923973.2022.2071723
Abstract: Abstract Background The inhaled sevoflurane (Sev) has been demonstrated to protect multiple organs against ischemia/reperfusion injury (IRI). However, the mechanisms of Sev in renal IRI remain largely unknown. This study intends to explore the effect… read more here.
Keywords: pathway; wnt catenin; iri; mir 374b ... See more keywords
MiR-374b promotes osteogenic differentiation of MSCs by degrading PTEN and promoting fracture healing.
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DOI: 10.26355/eurrev_201806_15149
Abstract: OBJECTIVE To investigate whether miR-374b can promote the differentiation of MSCs into osteoblasts by mediating PTEN, thus promoting fracture healing. MATERIALS AND METHODS Primary cultured mouse mesenchymal stem cells were obtained for following experiments. Flow… read more here.
Keywords: mir 374b; differentiation mscs; promoting fracture; mscs ... See more keywords
PTEN, A Target of Microrna-374b, Contributes to the Radiosensitivity of Canine Oral Melanoma Cells
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DOI: 10.3390/ijms20184631
Abstract: Canine oral malignant melanoma (CoMM) is often treated by radiation therapy in veterinary medicine. However, not all cases are successfully managed by this treatment. For improved efficacy of radiation therapy, biomarkers predicting the radiosensitivity of… read more here.
Keywords: mir 374b; melanoma; canine oral; kmec ... See more keywords