CircRPPH1 promotes the stemness of gastric cancer cells by targeting miR‐375/SLC7A11 axis
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23668
Abstract: This study mainly focuses on revealing the role of circRPPH1 in gastric cancer cell stemness. In vitro and in vivo experiments were performed to evaluate the effects of circRPPH1 on gastric cancer cell stemness. Luciferase… read more here.
Keywords: 375 slc7a11; cancer cells; mir 375; circrpph1 ... See more keywords
Micro-RNA-215 and -375 regulate thymidylate synthase protein expression in pleural mesothelioma and mediate epithelial to mesenchymal transition
Sign Up to like & getrecommendations! Published in 2022 at "Virchows Archiv"
DOI: 10.1007/s00428-022-03321-8
Abstract: The standard front-line treatment for pleural mesothelioma (PM) is pemetrexed-based chemotherapy, whose major target is thymidylate synthase (TS). In several cancer models, miR-215 and miR-375 have been shown to target TS, while information on these… read more here.
Keywords: expression; mir 215; 215 mir; mir 375 ... See more keywords
miR-375-3p contributes to hypoxia-induced apoptosis by targeting forkhead box P1 (FOXP1) and Bcl2 like protein 2 (Bcl2l2) in rat cardiomyocyte h9c2 cells.
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology letters"
DOI: 10.1007/s10529-020-03013-w
Abstract: miRNAs have been pointed to play critical role in the development of congenital heart disease (CHD). miRNA-375-3p (miR-375-3p) was involved in cardiac dysfunction and cardiogenesis. However, no prior study had established a therapeutic role of… read more here.
Keywords: h9c2 cells; apoptosis; bcl2l2; mir 375 ... See more keywords
CircTUBGCP3 Contributes to the Malignant Progression of Rectal Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-021-07135-7
Abstract: Circular RNA (circRNA) tubulin gamma complex associated protein 3 (circTUBGCP3) has been reported to play an oncogenic role in colorectal cancer and osteosarcoma. We further assessed the role and working mechanism of circTUBGCP3 in rectal… read more here.
Keywords: rectal cancer; circtubgcp3; mir 375; cancer cells ... See more keywords
An integrative bioinformatics analysis identified miR-375 as a candidate key regulator of malignant breast cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Applied Genetics"
DOI: 10.1007/s13353-019-00507-w
Abstract: MicroRNAs (miRNAs) are key regulators that play important biological roles in carcinogenesis and are promising biomarkers for cancer diagnosis and therapy. hsa-miR-375-3p (miR-375) has been suggested to serve as a tumor suppressor or oncogene in… read more here.
Keywords: malignant breast; analysis; breast cancer; mir 375 ... See more keywords
Circ_0001103 alleviates IL-1β-induced chondrocyte cell injuries by upregulating SIRT1 via targeting miR-375.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical immunology"
DOI: 10.1016/j.clim.2021.108718
Abstract: BACKGROUND Osteoarthritis (OA) is a common inflammatory disease characterized by articular cartilage degeneration and injury. Circular RNAs (circRNAs) are widely involved in the development of human diseases, including OA. The objective of this study was… read more here.
Keywords: sirt1; cell; circ 0001103; mir 375 ... See more keywords
microRNA‐375 modulates the NF‐&kgr;B pathway in miiuy croaker by targeting DUSP1 gene
Sign Up to like & getrecommendations! Published in 2018 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2018.05.010
Abstract: Abstract microRNAs (miRNAs) are highly conserved, small non‐coding endogenous molecule, and can participate in a variety of biological processes in organisms such as development, growth and immune response. Dual‐Specificity Phosphatases (DUSPs) are enzymes that can… read more here.
Keywords: miiuy croaker; dusp1 gene; mir 375; teleost fish ... See more keywords
Circular RNA 0060428 sponges miR-375 to promote osteosarcoma cell proliferation by upregulating the expression of RPBJ.
Sign Up to like & getrecommendations! Published in 2020 at "Gene"
DOI: 10.1016/j.gene.2020.144520
Abstract: Osteosarcoma (OS) is the most common primary bone tumor, and mainly occurs in children and early adults. The overall pathogenesis of osteosarcoma remains unclear. Circular RNAs (circRNAs) have been demonstrated to be one of the… read more here.
Keywords: circ 0060428; osteosarcoma; proliferation; mir 375 ... See more keywords
Tanshinone IIA harmonizes the crosstalk of autophagy and polarization in macrophages via miR‐375/KLF4 pathway to attenuate atherosclerosis
Sign Up to like & getrecommendations! Published in 2019 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2019.02.054
Abstract: Abstract Macrophages play a pivotal role in destabilizing atherosclerotic plaque. The diverse phenotypes and complex autophagy in macrophage are observed in atherosclerotic lesions. Tanshinone IIA (TNA) is known as the major component extracted from the… read more here.
Keywords: autophagy polarization; tna; tanshinone iia; mir 375 ... See more keywords
MicroRNA-375-3p in endothelial progenitor cells-derived extracellular vesicles relieves myocardial injury in septic rats via BRD4-mediated PI3K/AKT signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107740
Abstract: OBJECTIVE Sepsis can induce myocardial dysfunctions and endothelial progenitor cells (EPCs)-derived extracellular vesicles (EVs) can attenuate sepsis. Concerning to that, this article is intended to decode whether microRNA (miR)-375-3p in EPCs-EVs could affect myocardial injury… read more here.
Keywords: myocardial injury; mir 375; septic rats; epcs evs ... See more keywords
Label-free electrochemical quantification of microRNA-375 in prostate cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Electroanalytical Chemistry"
DOI: 10.1016/j.jelechem.2019.05.009
Abstract: Abstract Clinical applicability of a label-free electrochemical method was investigated, where prostate cancer (CaP) biomarkers miR-107 and miR-375 were examined in two different groups of prostate cell lines, metastatic CaP cells (PC-3, DU145, and LNCaP)… read more here.
Keywords: label free; prostate; free electrochemical; prostate cancer ... See more keywords