Articles with "mir 378" as a keyword



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CircRNA PLOD2 enhances ovarian cancer propagation by controlling miR-378

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Published in 2021 at "Saudi Journal of Biological Sciences"

DOI: 10.1016/j.sjbs.2021.06.088

Abstract: It has been confirmed that circular RNA participates in tumorgenesis through a variety of ways, so it may be used as a molecular marker for tumor diagnosis and treatment. In this study, the expression of… read more here.

Keywords: circ lopd2; expression; ovarian cancer; mir 378 ... See more keywords
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LncRNA PCFL promotes cardiac fibrosis via miR-378/GRB2 pathway following myocardial infarction.

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Published in 2019 at "Journal of molecular and cellular cardiology"

DOI: 10.1016/j.yjmcc.2019.06.011

Abstract: Long noncoding RNAs (lncRNAs) are a class of novel molecular regulators in cardiac development and diseases. However, the role of specific lncRNAs in cardiac fibrosis remains to be fully explored. The aim of the present… read more here.

Keywords: lncrna pcfl; pcfl; cardiac fibrosis; mir 378 ... See more keywords
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miR-378 and its host gene Ppargc1β exhibit independent expression in mouse skeletal muscle.

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Published in 2020 at "Acta biochimica et biophysica Sinica"

DOI: 10.1093/abbs/gmaa061

Abstract: MicroRNAs (miRNAs) are implicated in multiple biological processes in physiological and pathological settings. Nearly half of the known miRNAs are classified as 'intronic' miRNAs because they are embedded within the introns of protein-coding or noncoding… read more here.

Keywords: skeletal muscle; muscle; mir 378; expression ... See more keywords
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miR‐378‐3p alleviates contusion spinal cord injury by negatively regulating ATG12

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Published in 2021 at "International Journal of Experimental Pathology"

DOI: 10.1111/iep.12400

Abstract: MicroRNAs (miRNAs or miRs) serve essential roles in the pathogenic process of spinal cord injury (SCI). The present study investigated the role of miR‐378‐3p and autophagy‐related 12 (ATG12) in SCI. RT‐qPCR was used to detect… read more here.

Keywords: cord injury; sci; mir 378; spinal cord ... See more keywords
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Long noncoding RNA GAPLINC promotes gastric cancer cell proliferation by acting as a molecular sponge of miR-378 to modulate MAPK1 expression

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Published in 2018 at "OncoTargets and therapy"

DOI: 10.2147/ott.s165147

Abstract: Background Dysregulated long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) play key roles in the development of human cancers. LncRNA GAPLINC has been reported to be increased in gastric cancer (GC) tissues. Methods Real-time PCR assays… read more here.

Keywords: gaplinc; gastric cancer; mapk1 expression; mir 378 ... See more keywords
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EPA Modulates KLK Genes via miR-378: A Potential Therapy in Prostate Cancer

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14112813

Abstract: Simple Summary Castration resistant prostate cancer (CRPC) is one of the most pestilent form of prostate cancer (PCa), accounting for approximately 10–20% of all PCas, which carry poor mortality and morbidity rates. The focus in… read more here.

Keywords: cell; prostate cancer; prostate; mir 378 ... See more keywords
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Hormonal and Inflammatory Responses to Hypertrophy-Oriented Resistance Training at Acute Moderate Altitude

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Published in 2021 at "International Journal of Environmental Research and Public Health"

DOI: 10.3390/ijerph18084233

Abstract: This study investigated the effect of a traditional hypertrophy-oriented resistance training (RT) session at acute terrestrial hypoxia on inflammatory, hormonal, and the expression of miR-378 responses associated with muscular gains. In a counterbalanced fashion, 13… read more here.

Keywords: mir 378; inflammatory; oriented resistance; resistance training ... See more keywords
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MicroRNA-378 suppresses myocardial fibrosis through a paracrine mechanism at the early stage of cardiac hypertrophy following mechanical stress.

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Published in 2018 at "Theranostics"

DOI: 10.7150/thno.22878

Abstract: Rationale: Excessive myocardial fibrosis is the main pathological process in the development of cardiac remodeling and heart failure; therefore, it is important to prevent excessive myocardial fibrosis. We determined that microRNA-378 (miR-378) is cardiac-enriched and… read more here.

Keywords: mechanical stress; myocardial fibrosis; fibrosis; mir 378 ... See more keywords
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Hepatic miR-378 modulates serum cholesterol levels by regulating hepatic bile acid synthesis

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Published in 2021 at "Theranostics"

DOI: 10.7150/thno.53624

Abstract: Rationale: An improved understanding of thyroid hormone (TH) action on cholesterol metabolism will facilitate the identification of novel therapeutic targets for hypercholesterolemia. TH-regulated microRNAs (miRNAs) have been implicated in TH-controlled biological processes; however, whether and… read more here.

Keywords: hepatic mir; mir; mir 378; serum cholesterol ... See more keywords

miR-378 associated with proliferation, migration and apoptosis properties in A549 cells and targeted NPNT in COPD

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Published in 2022 at "PeerJ"

DOI: 10.7717/peerj.14062

Abstract: Background microRNAs contribute to the development and progression of chronic obstructive pulmonary disease (COPD). However, the underlying molecular mechanisms are largely unclear. The goal of this study was to investigate the roles of miR-378 in… read more here.

Keywords: copd; cell; proliferation; mir 378 ... See more keywords