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   Articles with "mir 379" as a keyword



Circular RNA circ-PITX1 promotes the progression of glioblastoma by acting as a competing endogenous RNA to regulate miR-379-5p/MAP3K2 axis.

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recommendations! Published in 2019 at "European journal of pharmacology"

DOI: 10.1016/j.ejphar.2019.172643

Abstract: As the most fatal disease in human central nerve system, glioblastoma has attracted increasing attention. Unfortunately, the prognosis for patients with glioblastoma still quite unfavorable. Recent years, circular RNAs (circRNAs) have been identified to be… read more here.

Keywords: glioblastoma; rna; mir 379; circ ... See more keywords

Blocking hsa_circ_0074027 suppressed non-small cell lung cancer chemoresistance via the miR-379-5p/IGF1 axis.

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recommendations! Published in 2021 at "Bioengineered"

DOI: 10.1080/21655979.2021.1987053

Abstract: Cancer cell chemoresistance is the primary reason behind cancer treatment failure. Previous reports suggest that circular RNA (circRNA) hsa_circ_0074027 (HC0074027) is a crucial modulator of non-small cell lung cancer (NSCLC) disease progression. Herein, we delineated… read more here.

Keywords: chemoresistance; mir 379; cancer; hsa circ ... See more keywords

MiR‐379‐5p inhibits the proliferation, migration, and invasion of breast cancer by targeting KIF4A

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recommendations! Published in 2022 at "Thoracic Cancer"

DOI: 10.1111/1759-7714.14437

Abstract: Many studies have shown that microRNAs (miRNAs) play an essential role in gene regulation and tumor development. This study aimed to explore the expression of miR‐379‐5p and its mechanisms of affecting proliferation, migration, and invasion… read more here.

Keywords: mir 379; proliferation migration; migration invasion; breast cancer ... See more keywords

Abstract P6-04-01: Engineering mesenchymal stem cells(MSCs) to secrete tumour-suppressing exosomes for breast cancer therapy

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recommendations! Published in 2017 at "Cancer Research"

DOI: 10.1158/1538-7445.sabcs16-p6-04-01

Abstract: Introduction: Mesenchymal Stem Cells(MSCs) are multipotent stromal cells that are known to engraft into tumours, raising their potential as tumour-targeted delivery vehicles. MSCs secrete tiny vesicles known as exosomes, which contain genetic material including microRNAs,… read more here.

Keywords: microscopy; breast cancer; mscs secrete; mir 379 ... See more keywords

Endogenous and extracellular roles of a tumor suppressor miR-379-5p in gastric cancer.

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recommendations! Published in 2025 at "Oncology"

DOI: 10.1159/000546620

Abstract: INTRODUCTION MiRNAs play important roles in development of various cancers including gastric cancer. Exosomes are extracellular vesicles for translocating molecules. This study aims to investigate the tumor suppressive roles of miR-379-5p in gastric cancer, and… read more here.

Keywords: gastric cancer; culture; 379 gastric; cell ... See more keywords

miR-379-3p activates the MAPK/JNK/p38 pathway by negatively targeting DUSP1 expression to promote myocardial ischemia-reperfusion injury

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recommendations! Published in 2025 at "Clinical Hemorheology and Microcirculation"

DOI: 10.1177/13860291251348806

Abstract: Background Myocardial ischemia-reperfusion injury (MI/RI) is a primary cause of cardiomyocyte death in various cardiovascular diseases. MicroRNAs (miRNAs) play significant roles in MI/RI. Objective This study aims to elucidate the function and mechanism of miR-379-3p… read more here.

Keywords: p38 pathway; jnk p38; injury; expression ... See more keywords

MiR-379-5p Promotes Chondrocyte Proliferation via Inhibition of PI3K/Akt Pathway by Targeting YBX1 in Osteoarthritis

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recommendations! Published in 2022 at "Cartilage"

DOI: 10.1177/19476035221074024

Abstract: Objective We evaluated the ability of miR-379-5p to influence the proliferation of osteoarthritis chondrocytes and elucidated the regulatory mechanism of miR-379-5p in osteoarthritis. Methods Real time polymerase chain reaction (RT- PCR) was used to detect… read more here.

Keywords: pi3k akt; mir 379; proliferation; osteoarthritis ... See more keywords
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Serum miR-379 expression is related to the development and progression of hypercholesterolemia in non-alcoholic fatty liver disease

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recommendations! Published in 2020 at "PLoS ONE"

DOI: 10.1371/journal.pone.0219412

Abstract: Introduction Non-alcoholic fatty liver disease (NAFLD) has a wide spectrum, eventually leading to cirrhosis and hepatic carcinogenesis. We previously reported that a series of microRNAs (miRNAs) mapped in the 14q32.2 maternally imprinted gene region (Dlk1-Dio3… read more here.

Keywords: non alcoholic; expression; mir 379; serum mir ... See more keywords

Transcriptome reveals key microRNAs involved in fat deposition between different tail sheep breeds

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recommendations! Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0264804

Abstract: MicroRNA (miRNA) is a kind of noncoding RNA whose function involved in various biological processes in neuronal maturation and adipocyte cells, such as differentiation, proliferation, development, apoptosis, and metabolism. Herein, miRNA-Seq was used to identify… read more here.

Keywords: mir 379; signaling pathway; fat deposition; sheep ... See more keywords

MiR-379 relieves myocardial injury after acute myocardial infarction by regulating tumor necrosis factor-α-induced protein 8.

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recommendations! Published in 2020 at "Panminerva medica"

DOI: 10.23736/s0031-0808.20.03929-4

Abstract: BACKGROUND Acute myocardial infarction (AMI) is the myocardial avascular necrosis syndrome caused by coronary atherosclerotic plaque rupture, thrombosis or coronary artery occlusion. Therefore, it is of great significance to find new targets for the treatment… read more here.

Keywords: mir 379; mir; necrosis; effect ... See more keywords

Granulosa cell-derived miR-379-5p regulates macrophage polarization in polycystic ovarian syndrome

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recommendations! Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1104550

Abstract: Polycystic ovarian syndrome (PCOS) is associated with hyperandrogenemia and ovarian antral follicle growth arrest. We have previously demonstrated that androgen-induced exosomal release of miR-379-5p (miR379) from preantral follicle granulosa cells increases the proliferation of target… read more here.

Keywords: macrophage polarization; mir 379; ovarian syndrome; granulosa ... See more keywords