N(6)-methyladenosine-mediated miR-380-3p maturation and upregulation promotes cancer aggressiveness in pancreatic cancer
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2088497
Abstract: ABSTRACT N(6)-methyladenosine (m6A)-modified microRNAs (miRNAs) are relevant to cancer progression. Also, although the involvement of miR-380-3p in regulating cancer progression in bladder cancer and neuroblastoma has been preliminarily explored, its role in other types of… read more here.
Keywords: pancreatic cancer; mir 380; progression; methyladenosine ... See more keywords
Nrf2-regulated miR-380-3p Blocks the Translation of Sp3 Protein and Its Mediation of Paraquat-Induced Toxicity in Mouse Neuroblastoma N2a Cells
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DOI: 10.1093/toxsci/kfz162
Abstract: Abstract Laboratorial and epidemiological research has established a relationship between paraquat (PQ) exposure and a risk for Parkinson’s disease. Previously, we have investigated the effects of nuclear factor erythroid 2 related factor 2 (Nrf2) and… read more here.
Keywords: sp3; induced toxicity; translation; mir 380 ... See more keywords
MiR-380 inhibits the proliferation and invasion of cholangiocarcinoma cells by silencing LIS1
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DOI: 10.1186/s12935-024-03241-4
Abstract: The objective of this study was to determine the role and regulatory mechanism of miR-380 in cholangiocarcinoma. The TargetScan database and a dual-luciferase reporter assay system were used to determine if LIS1 was a target… read more here.
Keywords: lis1; cholangiocarcinoma; mir 380; proliferation ... See more keywords