Articles with "mir 409" as a keyword



MiR‐409‐3p regulates cell proliferation and tumor growth by targeting E74‐like factor 2 in osteosarcoma

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Published in 2017 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12177

Abstract: Recent evidence has shown that miR‐409‐3p was down‐regulated in several types of cancer, including osteosarcoma. However, the potential role of miR‐409‐3p in osteosarcoma remains largely unknown. In the present study, we showed that overexpression of… read more here.

Keywords: cell proliferation; mir 409; osteosarcoma; tumor growth ... See more keywords
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Involvement of Early Embryonic miR-409-3p in the Establishment of Anxiety Levels in Female Mice.

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Published in 2020 at "Developmental neurobiology"

DOI: 10.1002/dneu.22756

Abstract: Small RNA molecules in early embryos delivered from sperm to zygotes upon fertilization are required for normal mouse embryonic development and even modest changes in the levels of sperm-derived miRNAs appear to influence early embryos… read more here.

Keywords: anxiety; mir 409; mice; early embryonic ... See more keywords

The role of miR‐409‐3p in regulation of HPV16/18‐E6 mRNA in human cervical high‐grade squamous intraepithelial lesions

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Published in 2019 at "Antiviral Research"

DOI: 10.1016/j.antiviral.2019.01.019

Abstract: ABSTRACT Cervical cancer is one of the most common malignancies in women. MicroRNAs (miRNAs) are involved in a variety of fundamental cellular processes, including carcinogenesis. The potential utilization of aberrantly expressed miRNAs as novel biomarkers… read more here.

Keywords: high grade; mir; mir 409; cervical cancer ... See more keywords

LncRNA ZEB1-AS1/miR-409-3p/ZEB1 feedback loop is involved in the progression of non-small cell lung cancer.

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Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.11.059

Abstract: Emerging evidence has illustrated that long noncoding RNA (LncRNA) ZEB1 antisense RNA 1 (ZEB1-AS1) involved in the development of various type of human cancers. However, the role of ZEB1-AS1 in non-small cell lung cancer (NSCLC)… read more here.

Keywords: mir 409; zeb1 as1; zeb1; lncrna zeb1 ... See more keywords
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MicroRNA-409-5p promotes retinal neovascularization in diabetic retinopathy

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Published in 2020 at "Cell Cycle"

DOI: 10.1080/15384101.2020.1749484

Abstract: ABSTRACT Background: Retinal neovascularization, which is characterized by the increased proliferation, migration, and tube formation of retinal microvascular endothelial cells (RMECs), contributes to the progression of diabetic retinopathy (DR). MiR-409-5p has been reported to be… read more here.

Keywords: proliferation migration; mir 409; tube formation; migration tube ... See more keywords

Circ_0001658 regulates gefitinib resistance of non-small cell lung cancer through miR-409-3p/TWIST1 axis.

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Published in 2021 at "Anti-cancer drugs"

DOI: 10.1097/cad.0000000000001257

Abstract: BACKGROUND To investigate the function and mechanism of circular RNA circ_0001658 on gefitinib resistance of non-small cell lung cancer (NSCLC) cells. METHODS Circ_0001658, microRNA (miRNA, miR)-409-3p and twist family bHLH transcription factor 1 (TWIST1) expression… read more here.

Keywords: expression; nsclc cells; circ 0001658; mir 409 ... See more keywords

Hsa‐miR‐409‐3p regulates endothelial progenitor senescence via PP2A‐P38 and is a potential ageing marker in humans

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Published in 2023 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.17691

Abstract: We explored the roles of hsa‐microRNA (miR)‐409‐3p in senescence and signalling mechanism of human endothelial progenitor cells (EPCs). Hsa‐miR‐409‐3p was found upregulated in senescent EPCs. Overexpression of miRNA mimics in young EPCs inhibited angiogenesis. In… read more here.

Keywords: mir 409; endothelial progenitor; young epcs; pp2a ... See more keywords

Investigation of the Disparities in Ultrasound Imaging Features of miR-323, miR-409-3p, and VEGF Expression Scales in Different Clinicopathological Features of Prostate Carcinoma and Their Correlation with Prognosis

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Published in 2022 at "BioMed Research International"

DOI: 10.1155/2022/5053204

Abstract: Prostate carcinoma (PC) is a disease of the male genitourinary system and a relatively common malignant tumor. In order to investigate the disparities in the expression of microRNA-323 (miR-323), microRNA-409-3p (miR-409-3p), and vascular endothelial growth… read more here.

Keywords: mir 323; mir 409; prognosis; vegf ... See more keywords

Abstract 3140: Upregulation Of Mirna-409-3p Contributes To Endothelial Cell Dysfunction In Patients With Diabetes

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Published in 2024 at "Arteriosclerosis, Thrombosis, and Vascular Biology"

DOI: 10.1161/atvb.44.suppl_1.3140

Abstract: Endothelial cell (EC) dysfunction is prevalent in individuals with insulin resistance and diabetes, characterized by diminished phosphorylation of endothelial nitric oxide synthase (p-eNOS) and reduced nitric oxide (NO) production in the endothelium. Despite its common… read more here.

Keywords: cell dysfunction; biology; dysfunction; endothelial cell ... See more keywords
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Exosomal miR-409-3p secreted from activated mast cells promotes microglial migration, activation and neuroinflammation by targeting Nr4a2 to activate the NF-κB pathway

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Published in 2021 at "Journal of Neuroinflammation"

DOI: 10.1186/s12974-021-02110-5

Abstract: Objective Neuroinflammation plays a critical role in central nervous system diseases. Exosomal miRNAs released from various cells are implicated in cell-to-cell communication. Prior studies have placed substantial emphasis on the role of cytokines in mast… read more here.

Keywords: mast cells; mir 409; neuroinflammation; migration activation ... See more keywords
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miR-409-3p inhibits the proliferation and migration of human ovarian cancer cells by targeting Rab10.

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Published in 2020 at "Cellular and molecular biology"

DOI: 10.14715/cmb/2020.66.7.30

Abstract: Ovarian cancer is a leading cause of gynecological cancer-related mortality. It has been reported that miR-409-3p is involved in the proliferation and migration of cancer cells. However, the role of miR-409-3p in ovarian cancer has… read more here.

Keywords: proliferation migration; mir 409; ovarian cancer; cancer cells ... See more keywords