Role of microRNA‐410 in molecular oncology: A double edged sword
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27251
Abstract: MicroRNAs (miRNAs) are short non‐coding single‐stranded RNAs, which play significant roles in the regulation of a myriad of biological processes. Overwhelmingly increasing high‐impact research has also deepened our understanding about the central role of miRNAs… read more here.
Keywords: role microrna; microrna 410; different cancers; oncology ... See more keywords
miR-410-3p Suppresses Cytokine Release from Fibroblast-Like Synoviocytes by Regulating NF-κB Signaling in Rheumatoid Arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation"
DOI: 10.1007/s10753-018-0896-2
Abstract: AbstractmiR-410-3p acts as an oncogene or a tumor suppressor in some malignancies. However, its role in rheumatoid arthritis (RA) is unknown. The study was conducted to investigate the effect of miR-410-3p on the pathogenesis of… read more here.
Keywords: 410 suppresses; fibroblast like; regulating signaling; like synoviocytes ... See more keywords
Lineage-dependent role of miR-410-3p as oncomiR in gonadotroph and corticotroph pituitary adenomas or tumor suppressor miR in somatotroph adenomas via MAPK, PTEN/AKT, and STAT3 signaling pathways
Sign Up to like & getrecommendations! Published in 2019 at "Endocrine"
DOI: 10.1007/s12020-019-01960-7
Abstract: PurposemiR-410-3p plays opposite roles in different cancers and may act as an oncomiR or tumor suppressor miR. The purpose of this study was to assess the role of miR-410-3p in somatotroph, gonadotroph, and corticotroph pituitary… read more here.
Keywords: gonadotroph corticotroph; tumor suppressor; mir; adenomas ... See more keywords
Inhibition of LncRNA-NEAT1 alleviates intestinal epithelial cells (IECs) dysfunction in ulcerative colitis by maintaining the homeostasis of the glucose metabolism through the miR-410-3p-LDHA axis
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2037957
Abstract: ABSTRACT Dysfunction of intestinal epithelial cells (IECs) leads to intestinal epithelial barrier damage and critically involves in the pathogenesis and development of ulcerative colitis (UC). Accumulating studies revealed essential functions of non-coding RNAs in UC.… read more here.
Keywords: glucose metabolism; dysfunction; mir 410; iecs ... See more keywords
Sex and tissue-specific downregulation of miR410-3p in a mouse model of cardiometabolic diseases
Sign Up to like & getrecommendations! Published in 2024 at "Physiology"
DOI: 10.1152/physiol.2024.39.s1.1508
Abstract: The brain Renin-Angiotensin System (RAS) plays a pivotal role in controlling cardiometabolic homeostasis, fluid balance, and other functions including inflammation. Previous studies have shown that more than a thousand microRNA (miRNA) families regulate RAS genes… read more here.
Keywords: mir410; physiology; mir 410; mouse model ... See more keywords
Abstract MP04: Brain miR-410-3p Expression Sex-dependently Reduces Ang-II-induced Hypertension
Sign Up to like & getrecommendations! Published in 2024 at "Hypertension"
DOI: 10.1161/hyp.81.suppl_1.mp04
Abstract: Dysregulation of microRNA (miRNA) is associated with hypertension and other diseases. We previously observed direct interaction of miR-410-3p with AT 1 R and sex-dependent downregulation of miR-410-3p in the hypothalamus of a mouse cardiometabolic disease… read more here.
Keywords: control; mir 410; ang; expression ... See more keywords
miR-410-3p is induced by vemurafenib via ER stress and contributes to resistance to BRAF inhibitor in melanoma
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0234707
Abstract: Despite significant development of melanoma therapies, death rates remain high. MicroRNAs, controlling posttranscriptionally gene expression, play role in development of resistance to BRAF inhibitors. The aim of the study was to assess the role of… read more here.
Keywords: melanoma; induced vemurafenib; mir 410; resistance braf ... See more keywords
MiR-410 induces stemness by inhibiting Gsk3β but upregulating β-catenin in non-small cells lung cancer
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14529
Abstract: Our previous research indicated miR-410 played a critical role in promoting the tumorigenesis and development of NSCLC (non-small cells lung cancer). MiR-410 has been recently reported to be crucial for development and differentiation of embryonic… read more here.
Keywords: mir 410; 410 induces; lung cancer; cancer ... See more keywords
Long noncoding RNA CCAT1 functions as a ceRNA to antagonize the effect of miR-410 on the down-regulation of ITPKB in human HCT-116 and HCT-8 cells
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.21612
Abstract: Colorectal cancer is one of the most common malignancies, which has seriously affected people's health. Abnormal expression of long non-coding RNAs and microRNAs are closely related to the process of occurrence, development, invasion and metastasis… read more here.
Keywords: itpkb; ccat1; human hct; lnc ccat1 ... See more keywords
MicroRNA-410-3p attenuates gemcitabine resistance in pancreatic ductal adenocarcinoma by inhibiting HMGB1-mediated autophagy
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.22494
Abstract: Gemcitabine-based chemotherapy is the most common treatment option for pancreatic ductal adenocarcinoma (PDAC). However, it offers little therapeutic value in many cases due to the rapid development of chemoresistance. MicroRNAs (miRNAs) have been found to… read more here.
Keywords: hmgb1; pdac; gemcitabine resistance; resistance ... See more keywords
Pinostrobin induces acute leukemia cell apoptosis via the regulation of miR-410-5p and SFRP5.
Sign Up to like & getrecommendations! Published in 2023 at "Life sciences"
DOI: 10.2139/ssrn.4379242
Abstract: AIMS This study attempted to explore the mechanisms involved in pinostrobin (PN)-mediated acute leukemia cell apoptosis regulated by miR-410-5p. MATERIAL AND METHODS NB4 and MOLT-4 cells were cultured and treated with PN at the IC50… read more here.
Keywords: mir 410; acute leukemia; leukemia cell; apoptosis ... See more keywords