LncRNA Snhg8 attenuates microglial inflammation response and blood–brain barrier damage in ischemic stroke through regulating miR‐425‐5p mediated SIRT1/NF‐κB signaling
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22724
Abstract: Increasing studies have indicated that abnormal expressed long noncoding RNAs (lncRNAs) play a vital role in ischemic stroke. Small nucleolar RNA host gene 8 (Snhg8), a member of lncRNAs, has been found to induce neuronal… read more here.
Keywords: sirt1; microglial inflammation; mir 425; inflammation ... See more keywords
Downregulation of long noncoding RNA SNHG7 protects against inflammation and apoptosis in Parkinson's disease model by targeting the miR‐425‐5p/TRAF5/NF‐κB axis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22867
Abstract: Accumulated evidence has manifested that long noncoding RNA (lncRNA) is involved in the progress of Parkinson's disease (PD). SNHG7, a novel lncRNA, has been found to be involved in tumorigenesis. However, SNHG7 expression and its… read more here.
Keywords: apoptosis; mir 425; rna; traf5 ... See more keywords
miR-425 regulates inflammatory cytokine production in CD4+ T cells via N-Ras upregulation in primary biliary cholangitis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2017.02.002
Abstract: BACKGROUND & AIMS Primary biliary cholangitis (PBC) is an autoimmune liver disease of unknown pathogenesis. Consequently, therapeutic targets for PBC have yet to be identified. CD4+ T cells play a pivotal role in immunological dysfunction… read more here.
Keywords: primary biliary; cd4 cells; via ras; pbc ... See more keywords
miR-425 suppresses EMT and the development of TNBC (triple-negative breast cancer) by targeting the TGF-β 1/SMAD 3 signaling pathway
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DOI: 10.1039/c8ra08872a
Abstract: EMT has a crucial effect on the progression and metastasis of tumors. read more here.
Keywords: emt development; tnbc triple; development tnbc; 425 suppresses ... See more keywords
Diverse Functions of MiR-425 in Human Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "DNA and cell biology"
DOI: 10.1089/dna.2022.0557
Abstract: miRNAs are a type of small endogenous noncoding RNA composed of 20-22 nucleotides that can regulate gene expression by targeting the 3' untranslated region of mRNA. Many investigations have discovered that miRNAs have a role… read more here.
Keywords: diverse functions; mir 425; 425 human; human cancer ... See more keywords
miR-425 regulates ovarian cancer proliferation, metastasis, and apoptosis by repressing PAK4 expression.
Sign Up to like & getrecommendations! Published in 2021 at "Asia-Pacific journal of clinical oncology"
DOI: 10.1111/ajco.13519
Abstract: AIM To explore the biological function of miR-425/PAK4 axis in proliferation, metastasis, and apoptosis of ovarian cancer (OC) cells. METHODS qRT-PCR and Western blot were adopted to examine miR-425 and PAK4 expressions in OC tissues… read more here.
Keywords: proliferation metastasis; mir 425; metastasis apoptosis; proliferation ... See more keywords
Serum miR-191 and miR-425 as Diagnostic and Prognostic Markers of Advanced Gastric Cancer Can Predict the Sensitivity of FOLFOX Chemotherapy Regimen
Sign Up to like & getrecommendations! Published in 2020 at "OncoTargets and therapy"
DOI: 10.2147/ott.s233086
Abstract: Purpose miR-191 and miR-425 have been proved to be highly expressed in gastric carcinoma (GC). However, little research has been done on their clinical value in serum of patients with advanced GC. In addition, it… read more here.
Keywords: folfox chemotherapy; mir 191; mir 425; 191 mir ... See more keywords
Potential role of miR-425, miR-155 and miR-33 in Streptococcus pneumoniae pneumonia by using bioinformatics analysis and experimental validation.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biological regulators and homeostatic agents"
DOI: 10.23812/21-120-a
Abstract: Streptococcus pneumoniae (S. pneumoniae) pneumonia is the most common cause of community-acquired pneumonia (CAP). Previous studies have suggested the diagnostic potential of microRNAs (miRNAs) in infectious diseases. In the present study, we aimed to evaluate… read more here.
Keywords: mir 155; pneumoniae pneumonia; 155 mir; mir ... See more keywords
MiR-425 involves in the development and progression of renal cell carcinoma by inhibiting E2F6.
Sign Up to like & getrecommendations! Published in 2018 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201810_16040
Abstract: OBJECTIVE To investigate the effect of miR-425 on the proliferation and apoptosis of clear cell renal carcinoma (ccRCA) cells, and to explore the underlying mechanism. PATIENTS AND METHODS A total of 80 pairs of human… read more here.
Keywords: carcinoma; ccrca; mir 425; proliferation ... See more keywords