Articles with "mir 429" as a keyword



Long noncoding RNA ZEB1-AS1 attenuates ferroptosis of gastric cancer cells through modulating miR-429/BGN axis.

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Published in 2023 at "Journal of biochemical and molecular toxicology"

DOI: 10.1002/jbt.23381

Abstract: Gastric cancer (GC) is the fifth utmost common malignant cancer type globally, in which ferroptosis acts a critical function in the progress of GC. Long noncoding RNA ZEB1-AS1 has been recognized in numerous cancers, but… read more here.

Keywords: zeb1 as1; bgn; ferroptosis; cancer ... See more keywords

Exosomes enriched by miR-429-3p derived from ITGB1 modified Telocytes alleviates hypoxia-induced pulmonary arterial hypertension through regulating Rac1 expression

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Published in 2024 at "Cell Biology and Toxicology"

DOI: 10.1007/s10565-024-09879-0

Abstract: Recent studies have emphasized the critical role of Telocytes (TCs)-derived exosomes in organ tissue injury and repair. Our previous research showed a significant increase in ITGB1 within TCs. Pulmonary Arterial Hypertension (PAH) is marked by… read more here.

Keywords: exo itgb1; itgb1; mir 429; itgb1 modified ... See more keywords

Long non-coding RNA Mirt2 relieves lipopolysaccharide-induced injury in PC12 cells by suppressing miR-429

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Published in 2019 at "Journal of Physiology and Biochemistry"

DOI: 10.1007/s13105-019-00691-7

Abstract: Long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) play important roles in the pathogenesis of spinal cord injury (SCI). This study investigated the effects of lncRNA Mirt2 and miR-429 on lipopolysaccharide (LPS)-induced injuries in PC12 cells.… read more here.

Keywords: pc12 cells; mir 429; long non; mirt2 ... See more keywords
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MiR-429 regulates the metastasis and EMT of HCC cells through targeting RAB23.

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Published in 2018 at "Archives of biochemistry and biophysics"

DOI: 10.1016/j.abb.2017.11.011

Abstract: Accumulating documents have revealed that microRNAs (miRNAs) play critical roles in the development and progression of tumors. MiR-429 has been reported to be involved in regulating various cellular processes. However, its biological role and underlying… read more here.

Keywords: mir 429; targeting rab23; hcc; hcc cells ... See more keywords

MicroRNA-429 inhibits bone metastasis in breast cancer by regulating CrkL and MMP-9.

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Published in 2019 at "Bone"

DOI: 10.1016/j.bone.2019.115139

Abstract: Bone metastasis is common in late-stage breast cancer patients and leads to skeletal-related events that affect the quality of life and decrease survival. Numerous miRNAs have been confirmed to be involved in metastatic breast cancer,… read more here.

Keywords: bone; mir 429; bone metastasis; breast cancer ... See more keywords

Long non-coding RNA MALAT1 sponges microRNA-429 to regulate apoptosis of hippocampal neurons in hypoxic-ischemic brain damage by regulating WNT1

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Published in 2019 at "Brain Research Bulletin"

DOI: 10.1016/j.brainresbull.2019.06.004

Abstract: Hypoxic-ischemic brain damage (HIBD) is a common neurological disorder. Emerging reports reveal that long non-coding RNAs and microRNAs (miRs) are implicated in the progress of HIBD. In this study we tried to ascertain whether lncRNA… read more here.

Keywords: apoptosis; mir 429; hibd; malat1 ... See more keywords

Inhibition of miR-429 improves neurological recovery of traumatic brain injury mice and attenuates microglial neuroinflammation.

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Published in 2019 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2019.106091

Abstract: BACKGROUND Neuroinflammation is a common therapeutic target for traumatic brain injury (TBI) due to its contribution to delayed secondary cell death and has the potential to occur for years after the initial insult. Previous studies… read more here.

Keywords: mir 429; neuroinflammation; mice; brain injury ... See more keywords

Knockdown of circ_0084043 suppresses the development of human melanoma cells through miR-429/tribbles homolog 2 axis and Wnt/β-catenin pathway.

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Published in 2020 at "Life sciences"

DOI: 10.1016/j.lfs.2020.117323

Abstract: AIMS Circular RNAs (circRNAs) have been emerged as novel regulators in multiple tumorigenesis, including melanoma. CircRNA_0084043 was recently demonstrated to be deregulated in human melanoma cells. Nevertheless, its role and mechanism are largely unrevealed in… read more here.

Keywords: melanoma; mir 429; catenin; circ 0084043 ... See more keywords

Inhibition of long non-coding RNA MALAT1 elevates microRNA-429 to suppress the progression of hypopharyngeal squamous cell carcinoma by reducing ZEB1.

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Published in 2020 at "Life sciences"

DOI: 10.1016/j.lfs.2020.118480

Abstract: OBJECTIVE Hypopharyngeal squamous cell carcinoma (HSCC) is a common type of malignant tumor. Long non-coding RNAs (lncRNAs) are known to participate in HSCC development, while the role of lncRNA MALAT1 in HSCC remains largely unknown.… read more here.

Keywords: related proteins; mir 429; malat1; zeb1 ... See more keywords

miR-429 suppresses tumor migration and invasion by targeting CRKL in hepatocellular carcinoma via inhibiting Raf/MEK/ERK pathway and epithelial-mesenchymal transition

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Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-20258-8

Abstract: Tumor metastasis is one of the main causes of hepatocellular carcinoma (HCC) high mortality. CRKL (v-crk sarcoma virus CT10 oncogene homologue (avian)-like) play important roles in tumor metastasis, however, the exact role and underlying mechanism… read more here.

Keywords: mir 429; crkl; migration invasion; raf mek ... See more keywords

MicroRNA-429 overexpression overcomes imatinib resistance of glioma cells by negatively regulating lysophosphatidic acid receptor 1

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Published in 2024 at "Neurological Research"

DOI: 10.1080/01616412.2024.2423586

Abstract: ABSTRACT Background Glioma is one of the most aggressive and lethal malignancies in central nervous system. It has been reported that miR-429 is declined in glioma and functions as a tumor suppressor. Nonetheless, the potential… read more here.

Keywords: mir 429; cell; resistance glioma; glioma cells ... See more keywords