CircTDRD3 aggravates H/R-induced cardiomyocyte apoptosis via targeting miR-4295/TP63 Axis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23003
Abstract: The myocardial cell injury resulted from Hypoxia/Reoxygenation is the main cause of acute myocardial infarction (AMI). There're many proofs showing the functions of circRNAs in the development of AMI. The study aimed at investigating the… read more here.
Keywords: mir 4295; apoptosis; circtdrd3; tp63 axis ... See more keywords
High expression of microRNA-4295 contributes to cell proliferation and invasion of pancreatic ductal adenocarcinoma by the down-regulation of Glypican-5.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.02.023
Abstract: A growing amount of evidence has documented that Glypican-5 (GPC5) is an important regulator of tumor progression. However, little is known about the role of GPC5 in pancreatic ductal adenocarcinoma (PDAC). In this study, we… read more here.
Keywords: proliferation invasion; pdac; gpc5; expression ... See more keywords
The paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine
Sign Up to like & getrecommendations! Published in 2020 at "Genes and Diseases"
DOI: 10.1016/j.gendis.2020.09.007
Abstract: Abstract MiR-4295, located on chromosome 10q25.2, is a unique miRNA with a wide range of biological functions. miR-4295 is widely expressed in vivo, participating in the biological processes of multiple cancers. Although miR-4295 is dysregulated in… read more here.
Keywords: medicine; paradoxical roles; roles mir; cancer ... See more keywords
Lycium barbarum polysaccharides alleviate hydrogen peroxide-induced injury by up-regulation of miR-4295 in human trabecular meshwork cells.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2018.12.007
Abstract: Glaucoma is a chronic neurodegenerative disease which produces damage to the optic nerve and causes sightlessness. Current remains lack of effective method for glaucoma. Lycium barbarum polysaccharides (LBPs) have pleiotropic effects on various diseases. However,… read more here.
Keywords: regulation mir; htm cells; lbps; h2o2 ... See more keywords