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   Articles with "mir 431" as a keyword



CircRNA circSTIL inhibits ferroptosis in colorectal cancer via miR‐431/SLC7A11 axis

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recommendations! Published in 2023 at "Environmental Toxicology"

DOI: 10.1002/tox.23670

Abstract: Ferroptosis is an emerging programmed cell death and plays essential roles in tumorigenesis, including colorectal cancer (CRC). The present study intended to disclose the role of a novel oncogene circular RNA (circRNA) circSTIL in CRC… read more here.

Keywords: circstil; cell; mir 431; slc7a11 ... See more keywords
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Circ_0002945 functions as a competing endogenous RNA to promote Aβ25-35-induced endoplasmic reticulum stress and apoptosis in SK-N-SH cells and human primary neurons

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recommendations! Published in 2022 at "Brain Research"

DOI: 10.1016/j.brainres.2022.147878

Abstract: BACKGROUND Circular RNAs (circRNAs) have been shown to function as competing endogenous RNAs (ceRNAs) to participate in the pathogenesis of Alzheimer's disease (AD). In this study, we set to identify the activity and mechanism of… read more here.

Keywords: reticulum stress; circ 0002945; circ; mir 431 ... See more keywords

Transcriptomic and functional studies reveal miR-431-5p as a tumour suppressor in pancreatic ductal adenocarcinoma cells.

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recommendations! Published in 2022 at "Gene"

DOI: 10.1016/j.gene.2022.146346

Abstract: The lactate receptor HCAR1 (hydroxycarboxylic acid receptor 1) is highly expressed in pancreatic ductal adenocarcinoma (PDAC), where it regulates lactate transport between the cancer cells. Little is known about the underlying cause of high HCAR1… read more here.

Keywords: hcar1; pancreatic ductal; mir 431; tumour suppressor ... See more keywords

circ_0072464 Shuttled by Bone Mesenchymal Stem Cell-Secreted Extracellular Vesicles Inhibits Nucleus Pulposus Cell Ferroptosis to Relieve Intervertebral Disc Degeneration

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recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/2948090

Abstract: Ferroptosis, as an iron-dependent form of necrotic cell death, has been reported to affect activities of nucleus pulposus cells (NPCs). However, its role in the pathogenesis of intervertebral disc degeneration (IDD) is largely unknown. Notably,… read more here.

Keywords: cell; circ 0072464; mir 431; intervertebral disc ... See more keywords

Circular RNA circCSPP1 promotes the occurrence and development of colon cancer by sponging miR-431 and regulating ROCK1 and ZEB1

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recommendations! Published in 2022 at "Journal of Translational Medicine"

DOI: 10.1186/s12967-022-03240-x

Abstract: Background Colon cancer is a common malignant tumor of the digestive tract, and its incidence is ranked third among gastrointestinal tumors. The present study aims to investigate the role of a novel circular RNA (circCSPP1)… read more here.

Keywords: circcspp1; mir 431; rock1; colon cancer ... See more keywords