Tanshinone I restrains osteosarcoma progression by regulating circ_0000376/miR-432-5p/BCL2 axis.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04257-4
Abstract: Circular RNAs (circRNAs) have been identified as important regulators in cancer progression. Nevertheless, little is known about the biological function of circ_0000376 in the progression of osteosarcoma (OS). Cell viability, colony formation ability, apoptosis, and… read more here.
Keywords: 0000376 mir; bcl2; mir 432; progression ... See more keywords
Circular RNA hsa_circ_0008039 promotes breast cancer cell proliferation and migration by regulating miR-432-5p/E2F3 axis.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.05.166
Abstract: As the development of sequencing technology, more and more circular RNAs (circRNAs) are identified in human cancer tissues. Increasing evidences imply circRNAs are important regulators in tumor progression. Nevertheless, how circRNAs participate in breast cancer… read more here.
Keywords: mir 432; hsa circ; breast cancer; circ 0008039 ... See more keywords
CircRNA SEPT9 contributes to malignant behaviors of glioma cells via miR-432-5p-mediated regulation of LASP1
Sign Up to like & getrecommendations! Published in 2021 at "Brain Research"
DOI: 10.1016/j.brainres.2021.147501
Abstract: BACKGROUND Circular RNA (circRNA) septin 9 (circSEPT9; hsa_circ_0005320) has been reported to be abnormally up-regulated in glioma. However, the exact role and working mechanism of circSEPT9 in glioma progression are barely known. METHODS RNA and… read more here.
Keywords: malignant behaviors; circsept9; glioma cells; mir 432 ... See more keywords
Circ_0075825 promotes gastric cancer progression via adsorbing miR-432-5p to modulate SOX9
Sign Up to like & getrecommendations! Published in 2022 at "Clinics"
DOI: 10.1016/j.clinsp.2022.100018
Abstract: Highlights • Circ_0075825 is highly expressed in gastric cancer tissues.• Circ_0075825 promotes the malignant biological behaviors of gastric cancer cells.• Circ_0075825 functions as a molecular sponge to repress miR-432-5p and up-regulate SOX9. read more here.
Keywords: mir 432; 0075825 promotes; circ 0075825; gastric cancer ... See more keywords
Circular RNA circRNA-0039459 promotes the migration, invasion, and proliferation of liver cancer cells through the adsorption of miR-432
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2073129
Abstract: ABSTRACT This study aimed to investigate the molecular mechanism of circular RNA circ-0039459 and its effects on the apoptosis, proliferation, invasion, and migration of hepatocellular carcinoma cells. The expression of circ-0039459, miR-432, and synoviolin 1… read more here.
Keywords: proliferation; circular rna; mir 432; circ 0039459 ... See more keywords
Circular RNA circ_0021093 regulates miR-432/Annexin A2 pathway to promote hepatocellular carcinoma progression
Sign Up to like & getrecommendations! Published in 2021 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001053
Abstract: Hepatocellular carcinoma (HCC) is a major histological subtype of liver cancer cases. Previous studies showed that circular RNA (circRNA) circ_0021093 was upregulated in HCC, but the regulatory mechanism of circ_0021093 is still rare. The expression… read more here.
Keywords: mir 432; hepatocellular carcinoma; hcc; circ 0021093 ... See more keywords
CircNEIL3 regulatory loop promotes pancreatic ductal adenocarcinoma progression via miRNA sponging and A-to-I RNA-editing
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Cancer"
DOI: 10.1186/s12943-021-01333-7
Abstract: Background A growing number of studies have focused on investigating circRNAs as crucial regulators in the progression of multiple cancer types. Nevertheless, the biological effects and underlying mechanisms of circRNAs in pancreatic ductal adenocarcinoma (PDAC)… read more here.
Keywords: pdac; rna editing; pancreatic ductal; ductal adenocarcinoma ... See more keywords