miR‐433‐3p suppresses bone formation and mRNAs critical for osteoblast function in mice
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4339
Abstract: MicroRNAs (miRNAs) are key posttranscriptional regulators of osteoblastic commitment and differentiation. miR‐433‐3p was previously shown to target Runt‐related transcription factor 2 (Runx2) and to be repressed by bone morphogenetic protein (BMP) signaling. Here, we show… read more here.
Keywords: bone; mir 433; differentiation; bone formation ... See more keywords
Long noncoding RNA SNHG14 promotes osteosarcoma progression via miR-433-3p/FBXO22 axis.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.01.016
Abstract: Long noncoding RNA small nucleolus RNA host gene 14 (SNHG14) has been shown to exert oncogenic functions in seceral cancers, but its role in osteosarcoma still unclear. In this present study, we found that SNHG14… read more here.
Keywords: long noncoding; noncoding rna; osteosarcoma; snhg14 ... See more keywords
Clinical significance of miR-433 in the diagnosis of Alzheimer's disease and its effect on Aβ-induced neurotoxicity by regulating JAK2
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2020.111080
Abstract: BACKGROUND Numerous microRNAs (miRNAs) have been investigated in the progression of Alzheimer's disease (AD). The purpose of this study was to analyze the expression of miR-433 and its diagnostic value in patients with AD, and… read more here.
Keywords: alzheimer disease; mir 433; induced neurotoxicity; expression ... See more keywords
Alteration of miR-21, miR-433 and miR-590 tissue expression related to the TGF-β signaling pathway in ulcerative colitis patients.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of physiology and biochemistry"
DOI: 10.1080/13813455.2020.1762656
Abstract: Ulcerative colitis (UC) is an inflammatory disease, and studies have suggested a role for TGF-β signalling pathway in the pathogenesis of UC. In the present study, we evaluated expression of TGF-β signalling genes and their… read more here.
Keywords: mir 590; mir mir; mir; tgf ... See more keywords
Circ_0003489 facilitates multiple myeloma progression by targeting miR-433-3p/PBX3 axis
Sign Up to like & getrecommendations! Published in 2022 at "Hematology"
DOI: 10.1080/16078454.2022.2109554
Abstract: ABSTRACT Background Multiple myeloma (MM) is a relatively common hematologic tumor, and the study of non-coding RNAs in MM is gradually increasing. Our study aimed to reveal the regulatory mechanism of circular RNA_0003489 (circ_0003489)/microRNA-433-3p (miR-433-3p)/Pre-B-cell… read more here.
Keywords: circ 0003489; 433 pbx3; mir 433; pbx3 axis ... See more keywords
Circ_0011292 knockdown mitigates progression and drug resistance in PTX-resistant non-small-cell lung cancer cells by regulating miR-433-3p/CHEK1 axis.
Sign Up to like & getrecommendations! Published in 2022 at "Thoracic cancer"
DOI: 10.1111/1759-7714.14378
Abstract: BACKGROUND Non-small-cell lung cancer (NSCLC) is one of the most common malignant tumors on earth. Circular RNAs have been disclosed to be vital regulators in the chemoresistance and development of diverse cancers, including NSCLC. Here,… read more here.
Keywords: mir 433; ptx; circ 0011292; cell ... See more keywords
Hsa_circ_0002496 promotes the growth, angiogenesis, and stemness of breast cancer cells via miR-433-3p/YWHAZ cascade.
Sign Up to like & getrecommendations! Published in 2023 at "Thoracic cancer"
DOI: 10.1111/1759-7714.14918
Abstract: BACKGROUND Breast cancer (BC) has been studied more and more in modern medicine. Circ_0002496 has established a critical role in BC. MiR-433-3p can exert important activity in cancer. YWHAZ can participate in BC development, but… read more here.
Keywords: circ 0002496; 433 ywhaz; mir 433;
HIF‐1α downregulation of miR‐433‐3p in adipocyte‐derived exosomes contributes to NPC progression via targeting SCD1
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Science"
DOI: 10.1111/cas.14829
Abstract: Resident adipocytes under a hypoxic tumor microenvironment exert an increasingly important role in cell growth, proliferation, and invasion in cancers. However, the communication between adipocytes and cancer cells during nasopharyngeal carcinoma (NPC) progression is poorly… read more here.
Keywords: hif; adipocyte derived; npc progression; expression ... See more keywords
RNA-Seq reveals miRNA role in thermogenic regulation in brown adipose tissues of goats
Sign Up to like & getrecommendations! Published in 2022 at "BMC Genomics"
DOI: 10.1186/s12864-022-08401-2
Abstract: Background MicroRNAs (miRNAs) are a family of short non-coding RNA molecules and play important roles in various biological processes. However, knowledge of the expression profiles and function of miRNAs on the regulation of brown adipose… read more here.
Keywords: mir 433; expression; regulation brown; brown adipose ... See more keywords
Depressive symptoms are associated with a functional polymorphism in a miR-433 binding site in the FGF20 gene
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Brain"
DOI: 10.1186/s13041-018-0397-0
Abstract: Genetic studies of major depressive disorder and its associated endophenotypes are useful for the identification of candidate genes. In recent years, variations in non-coding RNA genes, such as miRNAs, have been explored as novel candidates… read more here.
Keywords: depressive symptoms; functional polymorphism; fgf20 gene; mir 433 ... See more keywords
MicroRNA-433-3p promotes osteoblast differentiation through targeting DKK1 expression
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0179860
Abstract: Dickkopf-1 (DKK1) is a powerful antagonist of canonical WNT signaling pathway, and is regarded as a biomarker for osteoporosis. Its expression is highly correlated with bone mass and osteoblasts maturation. In this study, mouse primary… read more here.
Keywords: dkk1 expression; mir 433; expression; differentiation ... See more keywords