miR‐4458 regulates cell proliferation and apoptosis through targeting SOCS1 in triple‐negative breast cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28565
Abstract: Our previous study has suggested suppressor of cytokine signaling 1 (SOCS1) is associated with clinical progression and functions as an oncogenic role to regulate cell proliferation and apoptosis in triple‐negative breast cancer (TNBC). Several microRNA‐messenger… read more here.
Keywords: cell proliferation; mir 4458; cell; apoptosis ... See more keywords
MiR-4458/human antigen R (HuR) modulates PBX3 mRNA stability in melanoma tumorigenesis
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Dermatological Research"
DOI: 10.1007/s00403-020-02051-8
Abstract: Melanoma, a malignancy of the melanocyte, is characterized as the most fatal skin cancer with an increasing incidence. Of note, in spite of great attempts made for better treatment, the therapeutic outcome is barely satisfactory.… read more here.
Keywords: melanoma; pbx3 mrna; human antigen; hur ... See more keywords
LINC00963/miR-4458 regulates the effect of oxaliplatin in gastric cancer by mediating autophagic flux through targeting of ATG16L1.
Sign Up to like & getrecommendations! Published in 2021 at "Scientific reports"
DOI: 10.1038/s41598-021-98728-9
Abstract: Oxaliplatin resistance is the greatest obstacle to the management of local recurrence in gastric cancer patients after surgery. Accumulating evidence has suggested that inhibiting autophagy may be a novel approach for reversing resistance to oxaliplatin… read more here.
Keywords: gastric cancer; mir 4458; linc00963; sgc 7901 ... See more keywords
MiR-4458-loaded gelatin nanospheres target COL11A1 for DDR2/SRC signaling pathway inactivation to suppress the progression of estrogen receptor-positive breast cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm00543c
Abstract: RNA interference is a promising way to treat cancer and the construction of a stable drug delivery system is critically important for its application. Gelatin nanospheres (GNs) comprise a biodegradable drug vehicle with excellent biocompatibility,… read more here.
Keywords: breast cancer; mir 4458; col11a1; cancer ... See more keywords