MicroRNA-449c-5p inhibits osteogenic differentiation of human VICs through Smad4-mediated pathway
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DOI: 10.1038/s41598-017-09390-z
Abstract: Calcific aortic valve disease (CAVD) is the most common heart valve disorder, yet its mechanism remains poorly understood. Valve interstitial cells (VICs) are the prevalent cells in aortic valve and their osteogenic differentiation may be… read more here.
Keywords: valve; mir 449c; osteogenic differentiation; cavd ... See more keywords