TGF‐β/SMAD signaling inhibits intermittent cyclic mechanical tension‐induced degeneration of endplate chondrocytes by regulating the miR‐455‐5p/RUNX2 axis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27391
Abstract: A mechanical stimulation plays a pivotal role in maintaining normal cartilage function. Our objective was to reveal the mechanism of action of the tension‐sensitive molecule miR‐455‐5p in the degeneration of endplate chondrocytes and to identify… read more here.
Keywords: mir 455; endplate chondrocytes; degeneration endplate; tgf smad ... See more keywords
MiR‐455‐5p ameliorates HG‐induced apoptosis, oxidative stress and inflammatory via targeting SOCS3 in retinal pigment epithelial cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28755
Abstract: Diabetic retinopathy (DR) remains the leading cause of blindness in adults with diabetes mellitus. Numerous microRNAs (miRNAs) have been identified to modulate the pathogenesis of DR. The main purpose of this study was to evaluate… read more here.
Keywords: apoptosis; pigment epithelial; mir 455; stress ... See more keywords
MicroRNA‐455‐3p functions as a tumor suppressor by targeting HDAC2 to regulate cell cycle in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23516
Abstract: Hepatocellular carcinoma (HCC) is one of the most common cancers. MicroRNA has been studied more and more deeply and may become a new target for the treatment of HCC. Here, we investigated the role of… read more here.
Keywords: cell; hepatocellular carcinoma; hcc; cell cycle ... See more keywords
LncRNA promoted inflammatory response in ischemic heart failure through regulation of miR-455-3p/TRAF6 axis
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation Research"
DOI: 10.1007/s00011-020-01348-8
Abstract: Objectives Ischemic heart failure (IHF) is the most common cause of death globally. Growing evidence shows abnormal expression of long non-coding RNAs in heart failure patients. This study aims to investigate the effect of sex-determining… read more here.
Keywords: mir 455; inflammatory response; heart failure; sox2 ... See more keywords
Clinicopathological implications of TIM3+ tumor-infiltrating lymphocytes and the miR-455-5p/Galectin-9 axis in skull base chordoma patients
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-019-02349-1
Abstract: Chordoma is difficult to eradicate due to high local recurrence rates. The immune microenvironment is closely associated with tumor prognosis; however, its role in skull base chordoma is unknown. The expression of Galectin-9 (Gal9) and… read more here.
Keywords: mir 455; base chordoma; chordoma; skull base ... See more keywords
LncRNA XIST Promoted OGD-Induced Neuronal Injury Through Modulating/miR-455-3p/TIPARP Axis.
Sign Up to like & getrecommendations! Published in 2021 at "Neurochemical research"
DOI: 10.1007/s11064-021-03286-1
Abstract: In recent years, the incidence of ischemic stroke has gradually increased, but its pathogenesis has not been fully elucidated. lncRNAs played an important role in the occurrence and regulation of disease, but the research on… read more here.
Keywords: induced neuronal; xist; ogd induced; tiparp ... See more keywords
Mechanism of miR-455–3 in suppressing epithelial–mesenchymal transition and angiogenesis of non-small cell lung cancer cells
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DOI: 10.1007/s12192-022-01254-4
Abstract: The tumor-suppressing role of miR-455-3p has been reported in lung cancer, but the working mechanism remains to be fully elucidated. This study aims to explore the possible mechanism of miR-455-3p in regulating epithelial–mesenchymal transition (EMT)… read more here.
Keywords: hsf1; gls1; angiogenesis; nsclc cells ... See more keywords
miR-455-3p Is Negatively Regulated by Myostatin in Skeletal Muscle and Promotes Myoblast Differentiation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c02474
Abstract: Myostatin (MSTN) is a growth and differentiation factor that regulates proliferation and differentiation of myoblasts, which in turn controls skeletal muscle growth. It may regulate myoblast differentiation by influencing miRNA expression, and the present study… read more here.
Keywords: myoblast differentiation; expression; mir 455; differentiation ... See more keywords
Detection of increased serum miR-122-5p and miR-455-3p levels before the clinical diagnosis of liver cancer in people with type 2 diabetes
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DOI: 10.1038/s41598-021-03222-x
Abstract: People with type 2 diabetes (T2D) have increased cancer risk. Liver cancer (LC) has a high prevalence in East Asia and is one of the leading causes of cancer death globally. Diagnosis of LC at… read more here.
Keywords: cancer; mir; t2d; mir 455 ... See more keywords
miR-455-3p alleviates propofol-induced neurotoxicity by reducing EphA4 expression in developing neurons
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DOI: 10.1080/1354750x.2020.1832147
Abstract: Abstract Purpose Propofol, an aesthetic agent in paediatric patients, results in neurotoxicity in the developing neurons. To reduce side effects of propofol, the protective role of miR-455-3p (microRNA-455-3p) in developing rat brain was investigated. Materials… read more here.
Keywords: expression; developing neurons; propofol induced; cell ... See more keywords
MicroRNA-455-3p accelerate malignant progression of tumor by targeting H2AFZ in colorectal cancer
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DOI: 10.1080/15384101.2022.2154549
Abstract: ABSTRACT Colorectal cancer (CRC) becomes the second leading cause of cancer-related deaths in 2020. Emerging studies have indicated that microRNAs (miRNAs) play a key role in tumorigenesis and progression. The dysfunctions of miR-455-3p are observed… read more here.
Keywords: progression; mir 455; crc; colorectal cancer ... See more keywords