MiR‐483‐3p improves learning and memory abilities via XPO1 in Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2680
Abstract: Alzheimer's disease (AD), a common form of dementia, has been reported to influence 27 million individuals globally. Several risk factors including oxidative stress, gut microbiota imbalance, and cognitive activity are reported to be closely associated… read more here.
Keywords: 483 improves; improves learning; mir 483; alzheimer disease ... See more keywords
miR‐483 targets SMAD4 to suppress chondrogenic differentiation of human mesenchymal stem cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.23552
Abstract: MicroRNAs (miRNAs) can regulate cellular differentiation processes by modulating multiple pathways simultaneously. Previous studies to analyze in vivo miRNA expression patterns in developing human limb cartilage tissue identified significant downregulation of miR‐483 in hypertrophic chondrocytes… read more here.
Keywords: chondrogenesis; differentiation; expression; mir 483 ... See more keywords
Serum microRNA screening and functional studies reveal miR-483-5p as a potential driver of fibrosis in systemic sclerosis.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2017.12.015
Abstract: OBJECTIVE MicroRNAs (miRNAs) are regulatory molecules, which have been addressed as potential biomarkers and therapeutic targets in rheumatic diseases. Here, we investigated the miRNA signature in the serum of systemic sclerosis (SSc) patients and we… read more here.
Keywords: ssc patients; fibrosis; ssc; serum ... See more keywords
Circulating miR-320b and miR-483-5p levels are associated with COVID-19 in-hospital mortality
Sign Up to like & getrecommendations! Published in 2022 at "Mechanisms of Ageing and Development"
DOI: 10.1016/j.mad.2022.111636
Abstract: The stratification of mortality risk in COVID-19 patients remains extremely challenging for physicians, especially in older patients. Innovative minimally invasive molecular biomarkers are needed to improve the prediction of mortality risk and better customize patient… read more here.
Keywords: 320b mir; mir 483; mir 320b; mortality ... See more keywords
MicroRNA 483-3p targets Pard3 to potentiate TGF-β1-induced cell migration, invasion, and epithelial–mesenchymal transition in anaplastic thyroid cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "Oncogene"
DOI: 10.1038/s41388-018-0447-1
Abstract: Anaplastic thyroid cancer (ATC) is associated with poor prognosis and is often untreatable. MicroRNA 483-3p (miR-483) and partitioning-defective 3 (Pard3), a member of the Pard family, have functions and regulatory mechanisms in ATC. The abnormal… read more here.
Keywords: invasion; thyroid cancer; migration; mir 483 ... See more keywords
Effect of Benzo(a)pyrene on the Expression of miR-483-3p in Hepatocyte Primary Culture and Rat Liver
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry (Moscow)"
DOI: 10.1134/s0006297919100080
Abstract: Here, we suggested that the epigenetic mechanism of benzo(a)pyrene (BP) action might be based on the aryl hydrocarbon receptor (AhR)-mediated transcription of the target genes, including miRNAs, that have the dioxin response element (DRE) in… read more here.
Keywords: expression; benzo pyrene; mir 483; expression mir ... See more keywords
Endothelial MicroRNA-483-3p Is Hypertension-Protective
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/3698219
Abstract: Hypertension is a high-risk factor for developing coronary heart disease and stroke. Endothelial dysfunction and arterial remodeling can lead to increased vascular wall thickness and arterial stiffness. Previous studies showed that microRNA-483 (miR-483) enhances endothelial… read more here.
Keywords: mir 483; 483 hypertension; microrna 483; hypertension ... See more keywords
MiR-483 Promotes Colorectal Cancer Cell Biological Progression by Directly Targeting NDRG2 through Regulation of the PI3K/AKT Signaling Pathway and Epithelial-to-Mesenchymal Transition
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Healthcare Engineering"
DOI: 10.1155/2022/4574027
Abstract: Background Colorectal cancer is the third frequent tumor in the whole world. MiR-483, located at the 11p15.5 locus, acts as an oncogene in multiple tumors. The purpose of this study is to explore the important… read more here.
Keywords: mir 483; pi3k akt; colorectal cancer; cell ... See more keywords
Next-generation sequencing reveals microRNA markers of adrenocortical tumors malignancy
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.16788
Abstract: Background Adrenocortical carcinoma is a rare finding among common adrenocortical tumors, but it is highly aggressive and requires early detection and treatment. Still, the differential diagnosis between benign and malignant lesions is difficult even for… read more here.
Keywords: malignancy; adrenocortical tumors; mir 483; next generation ... See more keywords
MiR-483 Targeted SOX3 to Suppress Glioma Cell Migration, Invasion and Promote Cell Apoptosis
Sign Up to like & getrecommendations! Published in 2020 at "OncoTargets and therapy"
DOI: 10.2147/ott.s240619
Abstract: Objective Glioma is the most common malignant brain tumor that has high aggressiveness. The aim of this study was to investigate the potential therapeutic targets for gliomas. Materials and Methods Real-time quantitative polymerase chain reaction… read more here.
Keywords: glioma; invasion; mir 483; apoptosis ... See more keywords
Diagnostic Potential of Plasma Extracellular Vesicle miR-483-3p and Let-7d-3p for Sepsis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.814240
Abstract: Background: microRNAs (miRNAs) from circulating extracellular vesicles (EVs) have been reported as disease biomarkers. This study aimed to identify the diagnostic value of plasma EV-miRNAs in sepsis. Methods: EVs were separated from the plasma of… read more here.
Keywords: sepsis; plasma; 483 let; mir 483 ... See more keywords