miR‐485's anti‐drug resistant epilepsy effects by regulating SV2A/PSD‐95 and targeting ABCC1 and neuronal signaling‐transduction proteins in hippocampus of rats
Sign Up to like & getrecommendations! Published in 2021 at "Brain and Behavior"
DOI: 10.1002/brb3.2247
Abstract: Drug‐resistant epilepsy (DRE), most subsequently developing refractory epilepsy, causes a significant burden to the society. microRNAs have been demonstrated as key regulators and therapeutic targets in epilepsy. Accordingly, the aim of the present study was… read more here.
Keywords: epilepsy; mir 485; resistant epilepsy; drug resistant ... See more keywords
Epigallocatechin‐3‐gallate inhibited cancer stem cell–like properties by targeting hsa‐mir‐485‐5p/RXRα in lung cancer
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27117
Abstract: Non–small‐cell lung cancer (NSCLC) appears to be a significant threat to public health worldwide. MicroRNAs have been identified as significant regulators for the development of NSCLC. Previous reports have suggested that hsa‐mir‐485‐5p is dysregulated in… read more here.
Keywords: cancer; hsa mir; mir 485; rxr ... See more keywords
LncRNA RHPN1-AS1 accelerates proliferation, migration, and invasion via regulating miR-485-5p/BSG axis in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-020-01889-z
Abstract: It is reported that long noncoding RNA RHPN1-AS1 (lncRNA RHPN1-AS1) functions as an oncogene among multiple types of cancers; however, the effect of lncRNA RHPN1-AS1 in hepatocellular carcinoma (HCC) is left to be investigated. The… read more here.
Keywords: lncrna rhpn1; bsg; rhpn1 as1; mir 485 ... See more keywords
miR-485-5p suppresses breast cancer progression and chemosensitivity by targeting survivin.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.04.129
Abstract: Breast cancer is the most common cancer among women worldwide. Chemoresistance remains to be a considerable obstacle in breast cancer therapy and it is often involves dysregulation of a variety of microRNAs (miRNAs). miR-485-5p functions… read more here.
Keywords: mir 485; chemosensitivity; breast cancer; 485 suppresses ... See more keywords
miR-485-5p suppresses Schwann cell proliferation and myelination by targeting cdc42 and Rac1.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2019.111803
Abstract: Schwann cells, a crucial element in peripheral nervous system, play important roles after peripheral nerve injury. In recent years, the role of miR-485-5p has been discovered in neurological diseases. However, the involvement of miR-485-5p and… read more here.
Keywords: mir 485; schwann cells; proliferation; nerve ... See more keywords
Circular RNA PLCE1 promotes epithelial mesenchymal transformation, glycolysis in colorectal cancer and M2 polarization of tumor-associated macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2003929
Abstract: ABSTRACT Plentiful studies have clarified that circular RNAs (circRNAs) are crucial in colorectal cancer (CRC)’s occurrence and development, but its function has not been fully elucidated. The purpose of this study was to investigate the… read more here.
Keywords: tam polarization; tumor; crc; glycolysis ... See more keywords
CircFOXK2 enhances tumorigenesis and immune evasion in non–small cell lung cancer by miR-485-5p/PD-L1 axis
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001287
Abstract: Background Circular RNAs (circRNAs) serve a key role in lots of cancers. The outcomes of upregulated circular RNA forkhead box K2 (circFOXK2) on non–small cell lung cancer (NSCLC) persisted uncertainly. In this study, the role… read more here.
Keywords: cell; non small; tumorigenesis; circfoxk2 ... See more keywords
CircHECTD1 up-regulates mucin 1 expression to accelerate hepatocellular carcinoma development by targeting microRNA-485-5p via a competing endogenous RNA mechanism
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000000917
Abstract: Abstract Background: Non-coding RNAs have attracted considerable attention for their vital role in cancer. The purpose of this study was to determine the effects of non-coding RNAs on hepatocellular carcinoma (HCC) and reveal their regulatory… read more here.
Keywords: expression; hepatocellular carcinoma; mir 485; mechanism ... See more keywords
Exosomal miR-485-3p derived from pancreatic ductal epithelial cells inhibits pancreatic cancer metastasis through targeting PAK1
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DOI: 10.1097/cm9.0000000000002154
Abstract: Abstract Background: Cell competition is an important feature in pancreatic cancer (PC) progression, but the underlying mechanism remains elusive. This study aims to explore the role of exosomes derived from normal pancreatic ductal epithelial cells… read more here.
Keywords: metastasis; pak1; epithelial cells; pancreatic ductal ... See more keywords
MiR‐200c‐3p and miR‐485‐5p overexpression elevates cisplatin sensitivity and suppresses the malignant phenotypes of non–small cell lung cancer cells through targeting RRM2
Sign Up to like & getrecommendations! Published in 2022 at "Thoracic Cancer"
DOI: 10.1111/1759-7714.14475
Abstract: This study intended to investigate the potential mechanism of microRNA‐200c‐3p (miR‐200c‐3p) and miR‐485‐5p in mediating the cisplatin (DDP) resistance in non–small cell lung cancer (NSCLC). read more here.
Keywords: non small; mir 200c; 200c mir; mir ... See more keywords
Influence of CTNNB1 rs2953 polymorphism on schizophrenia susceptibility in Chinese Han population through modifying miR‐485 binding to CTNNB1
Sign Up to like & getrecommendations! Published in 2019 at "Genes"
DOI: 10.1111/gbb.12524
Abstract: Schizophrenia (SCZ) and bipolar disorder (BD) are two major neuropsychiatric diseases that are the most substantial causes of disability and mortality worldwide. CTNNB1 encodes beta‐catenin, an important protein in canonical Wnt signaling. We aimed to… read more here.
Keywords: scz; mir 485; binding ctnnb1; ctnnb1 rs2953 ... See more keywords