miR-492 promotes chemoresistance to CDDP and metastasis by targeting inhibiting DNMT3B and induces stemness in gastric cancer
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20194342
Abstract: Abstract Objective: Metastasis and chemoresistance indicate treatment fail and progresses in gastric cancer (GC) patients. However, the molecular mechanisms of chemoresistance and metastasis remain unclear in GC. Thus, identifying the biological indicators of chemoresistance and… read more here.
Keywords: metastasis; gastric cancer; mir 492; chemoresistance ... See more keywords
NamiRNA-enhancer network of miR-492 activates the NR2C1-TGF-β/Smad3 pathway to promote epithelial-mesenchymal transition of pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Carcinogenesis"
DOI: 10.1093/carcin/bgac102
Abstract: Pancreatic cancer (PaCa) is one of the most fatal malignancies of the digestive system, and most patients are diagnosed at advanced stages due to the lack of specific and effective tumor-related biomarkers for the early… read more here.
Keywords: mir 492; pancreatic cancer; tgf smad3; promote epithelial ... See more keywords