LncRNA ATB promotes proliferation and metastasis in A549 cells by down‐regulation of microRNA‐494
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26894
Abstract: Lung cancer is a commonly diagnosed disease with poor prognosis. Novel therapeutic targets and deep understanding of the regulatory mechanisms in lung cancer are of great importance. We aimed to figure out the functional roles… read more here.
Keywords: a549 cells; mir 494; a549; proliferation ... See more keywords
Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2018.11.067
Abstract: Background Astrocytes regulate neuronal function, synaptic formation and maintenance partly through secreted extracellular vesicles (EVs). In amyotrophic lateral sclerosis (ALS) astrocytes display a toxic phenotype that contributes to motor neuron (MN) degeneration. Methods We used… read more here.
Keywords: extracellular vesicles; mir 494; network; astrocyte derived ... See more keywords
miR-494-3p modulates the progression of in vitro and in vivo Parkinson’s disease models by targeting SIRT3
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.03.037
Abstract: Parkinson's disease (PD) is the second most prevalent chronic and progressive neurodegenerative disease. Plenty of miRNAs have been demonstrated to participate in the pathogenesis of PD. However, the detailed roles of miR-494-3p and underlying mechanisms… read more here.
Keywords: mir 494; targeting sirt3; disease; expression ... See more keywords
MiR-494 acts as a tumor promoter by targeting CASP2 in non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-39453-2
Abstract: MiR-494 plays an important role in several types of human cancers, including non-small cell lung cancer (NSCLC). Although the role of miR-494 has been investigated in several studies, the expression profile and underlying mechanism are… read more here.
Keywords: non small; targeting casp2; mir 494; cell lung ... See more keywords
Circular RNA circ_0081001 knockdown enhances methotrexate sensitivity in osteosarcoma cells by regulating miR-494-3p/TGM2 axis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Orthopaedic Surgery and Research"
DOI: 10.1186/s13018-020-02169-5
Abstract: Background Circular RNAs (circRNAs) have been shown to participate in the chemoresistance and tumorigenesis of multiple cancers. The purpose of this research was to investigate the function of circ_0081001 in methotrexate (MTX) resistance of osteosarcoma… read more here.
Keywords: tgm2; mir 494; 0081001 knockdown; circ 0081001 ... See more keywords
The regulating role of miR-494 on HCCR1 in cervical cancer cells.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2021.67.5.18
Abstract: This study focused on miR-494 inhibiting the proliferation, migration and invasion of cervical cancer cells by regulating HCCR1. During the study, 30 pairs of primary cervical cancer tissues and adjacent tissues diagnosed by pathology were… read more here.
Keywords: cervical cancer; cancer; cells regulating; regulating role ... See more keywords
LncRNA WT1-AS/miR-494-3p Regulates Cell Proliferation, Apoptosis, Migration and Invasion via PTEN/PI3K/AKT Signaling Pathway in Non-Small Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2021 at "OncoTargets and therapy"
DOI: 10.2147/ott.s278233
Abstract: Background Non-small cell lung cancer (NSCLC) is one of the most common malignancies with the highest morbidity and mortality worldwide. Long non-coding RNAs (lncRNAs) are recently recognized as noteworthy regulators of different tumors, counting NSCLC.… read more here.
Keywords: cell proliferation; mir 494; nsclc cell; wt1 mir ... See more keywords
microRNA-494 Favors HO-1 Expression in Neuroblastoma Cells Exposed to Oxidative Stress in a Bach1-Independent Way
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2018.00199
Abstract: Heme oxygenase 1 (HO-1) is crucially involved in cell adaptation to oxidative stress and has been demonstrated to play an important role in cancer progression and resistance to therapies. We recently highlighted that undifferentiated neuroblastoma… read more here.
Keywords: mir 494; stress; bach1; induction ... See more keywords
miR‑494‑BAG‑1 axis is involved in cinobufacini‑induced cell proliferation and apoptosis in gastric cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular medicine reports"
DOI: 10.3892/mmr.2018.8788
Abstract: Cinobufacini is widely used in the treatment of advanced cancers. It has been previously reported that microRNA (miR)‑494 was upregulated in cinobufacini‑treated gastric cancer cells; however, the detailed role of miR‑494 in the anti‑tumor activity… read more here.
Keywords: mir 494; bag; gastric cancer; proliferation ... See more keywords
Down-regulation of BMAL1 by MiR-494-3p Promotes Hepatocellular Carcinoma Growth and Metastasis by Increasing GPAM-mediated Lipid Biosynthesis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.74951
Abstract: The circadian clock confers daily rhythmicity to many crucial biological processes and behaviors and its disruption is closely associated with carcinogenesis in several types of cancer. Brain and muscle arnt-like protein 1 (BMAL1) is a… read more here.
Keywords: hepatocellular carcinoma; hcc; bmal1; regulation bmal1 ... See more keywords
Increased Expression of miR-494 in Serum of Patients with Prostate Cancer and its Potential Diagnostic Value.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical laboratory"
DOI: 10.7754/clin.lab.2019.190422
Abstract: BACKGROUND Prostate cancer is a common male cancer with poor prognosis, and to find molecular diagnostic markers for the early diagnosis of prostate cancer is urgently needed. The aim of this study is to investigate… read more here.
Keywords: expression; mir 494; cancer; prostate cancer ... See more keywords