Articles with "mir 495" as a keyword



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miR‐495 and miR‐5688 are down‐regulated in non‐small cell lung cancer under hypoxia to maintain interleukin‐11 expression

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Published in 2020 at "Cancer Communications"

DOI: 10.1002/cac2.12076

Abstract: Hypoxia is a hallmark of cancer and is associated with poor prognosis. However, the molecular mechanism by which hypoxia promotes tumor progression remains unclear. MicroRNAs dysregulation has been shown to play a critical role in… read more here.

Keywords: hypoxia; mir 495; mir 5688; non small ... See more keywords
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Evaluation of the circulating MicroRNA‐495 and Stat3 as prognostic and predictive biomarkers for lower extremity deep venous thrombosis

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Published in 2018 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.26633

Abstract: This study aims to elucidate the prognostic and predictive biomarker of miR‐495 and Stat3 in peripheral blood in relation to lower extremity deep venous thrombosis (DVT). Patients with lower limb fractures were assigned into case… read more here.

Keywords: lower extremity; mir 495; stat3; prognostic predictive ... See more keywords
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NEAT1 promotes colon cancer progression through sponging miR‐495‐3p and activating CDK6 in vitro and in vivo

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Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.28557

Abstract: Recently, increasing evidence has indicated lncRNAs are powerful regulators in the progression of multiple tumors. Dysregulation of lncRNA NEAT1 has been recognized in many cancer types. Meanwhile, the studies on NEAT1 function have suggested that… read more here.

Keywords: cancer; mir 495; colon cancer; cancer progression ... See more keywords
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Long noncoding RNA NEAT1 sponges miR‐495‐3p to enhance myocardial ischemia‐reperfusion injury via MAPK6 activation

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Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.28791

Abstract: The biological function of long noncoding RNA NEAT1 has been revealed in a lot of diseases. Nevertheless, it is still not yet clear whether NEAT1 can modulate the process of myocardial ischemia–reperfusion injury (M‐I/R). Here,… read more here.

Keywords: long noncoding; rna neat1; noncoding rna; mir 495 ... See more keywords
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MicroRNA-495 alleviates ulcerative interstitial cystitis via inactivating the JAK–STAT signaling pathway by inhibiting JAK3

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Published in 2021 at "International Urogynecology Journal"

DOI: 10.1007/s00192-020-04593-x

Abstract: As a notable chronic disorder, the incidence of interstitial cystitis (IC) has been documented to have increased among the female population with activity in microRNA-495 (miR-495) implicated in this disease. The current study was aimed… read more here.

Keywords: jak3; mir 495; interstitial cystitis; jak stat ... See more keywords
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Circ_0030411 aggravates cisplatin-resistance in non-small cell lung cancer by serving as a miR-495-3p sponge to enhance CCND1 expression.

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Published in 2023 at "Journal of chemotherapy"

DOI: 10.1080/1120009x.2022.2162218

Abstract: Circular RNAsplay important modulators in cisplatin (DDP) resistant non-small cell lung cancer (NSCLC). Herein, the role and mechanism of circ_0030411 in DDP-resistant NSCLC was explored. Circ_0030411, miR-495-3p, CCND1, PCNA, Bax, E-cadherin, and ki-67 expression were… read more here.

Keywords: cell; circ 0030411; ccnd1; ddp resistant ... See more keywords
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Induction of lncRNA NORAD accounts for hypoxia-induced chemoresistance and vasculogenic mimicry in colorectal cancer by sponging the miR-495-3p/ hypoxia-inducible factor-1α (HIF-1α)

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2021.2015530

Abstract: ABSTRACT Hypoxic microenvironment represents the hallmark of solid tumors including colorectal cancer (CRC) and facilitates angiogenesis and chemoresistance, leading to poor prognosis. lncRNA NORAD acts as an oncogenic gene to orchestrate cancer progression by regulating… read more here.

Keywords: mir 495; cancer; hif; hypoxia induced ... See more keywords
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Long non-coding RNA-non-coding RNA activated by DNA damage inhibition suppresses hepatic stellate cell activation via microRNA-495-3p/sphingosine 1-phosphate receptor 3 axis

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2037841

Abstract: ABSTRACT Hepatic fibrosis is a damage repair response caused by multiple factors. A growing body of research suggests that long non-coding RNAs (lncRNAs) are involved in a wide range of biological processes, and thus regulate… read more here.

Keywords: hepatic fibrosis; non coding; coding rna; mir 495 ... See more keywords
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MicroRNA‐495‐3p diminishes doxorubicin‐induced cardiotoxicity through activating AKT

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Published in 2022 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.17230

Abstract: Doxorubicin (Dox) is a broad‐spectrum antitumour agent; however, its clinical application is impeded due to the cumulative cardiotoxicity. The present study aims to investigate the role and underlying mechanisms of microRNA‐495‐3p (miR‐495‐3p) in Dox‐induced cardiotoxicity.… read more here.

Keywords: induced cardiotoxicity; microrna 495; dox induced; cardiotoxicity ... See more keywords
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The Potential of miR-370-3p and miR-495-3p Serving as Biomarkers for Sepsis-Associated Acute Kidney Injury

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Published in 2022 at "Computational and Mathematical Methods in Medicine"

DOI: 10.1155/2022/2439509

Abstract: Objective This study is aimed at evaluating the miR-370-3p and miR-495-3p expression in the urine of patients with sepsis-associated acute kidney injury (SA-AKI) and exploring its diagnosis value in for SA-AKI. Methods 184 sepsis invalids… read more here.

Keywords: aki; mir 370; 370 mir; mir ... See more keywords
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The MiR-495/Annexin A3/P53 Axis Inhibits the Invasion and EMT of Colorectal Cancer Cells

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Published in 2017 at "Cellular Physiology and Biochemistry"

DOI: 10.1159/000485877

Abstract: Background/Aims: More and more reports have shown that the dysregulation of miRNAs can contribute to the progression and metastasis of human cancers. Many studies have shown that the down-regulation of the miR-495 level occurs in… read more here.

Keywords: crc cells; mir 495; invasion emt; annexin ... See more keywords