Functional miR-146a, miR-149, miR-196a2 and miR-499 polymorphisms and the susceptibility to hepatocellular carcinoma: An updated meta-analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2017.03.005
Abstract: OBJECTIVE Single nucleotide polymorphisms of miRNAs play important roles in the pathogenesis of hepatocellular carcinoma (HCC). To evaluate the association between four common miRNAs (miR-146a rs2910164; miR-149 rs2292832; miR-196a2 rs11614913 and miR-499 rs3746444) and HCC… read more here.
Keywords: mir 196a2; hcc; mir 149; mir 146a ... See more keywords
Comparison of miRNA signature versus conventional biomarkers before and after off‐pump coronary artery bypass graft
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2016.11.014
Abstract: HIGHLIGHTSPlasma microRNAs have advantages over conventional biomarkers for cardiac injuries.There is a strong correlation between plasma miR‐499 and cTnI in CABG patients.A strong correlation exists between plasma miR‐126 and uric acid in CABG patients.Release of… read more here.
Keywords: artery; mir 126; mir; conventional biomarkers ... See more keywords
Hyperoside ameliorates diabetic nephropathy induced by STZ via targeting the miR-499-5p/APC axis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmacological sciences"
DOI: 10.1016/j.jphs.2021.02.005
Abstract: Diabetic nephropathy is a serious complication of diabetes. Hyperoside has been widely reported to ameliorate diabetes-associated disease. The current study is designed to explore the mechanism of hyperoside in diabetic nephropathy. In the present study,… read more here.
Keywords: hyperoside ameliorates; apc; ameliorates diabetic; diabetic nephropathy ... See more keywords
Plasma miR-208b and miR-499: Potential Biomarkers for Severity of Coronary Artery Disease
Sign Up to like & getrecommendations! Published in 2019 at "Disease Markers"
DOI: 10.1155/2019/9842427
Abstract: Aims MicroRNAs (miRNAs) are associated with the pathogenesis of coronary artery disease (CAD). The objective of this study is to explore plasma levels of miR-208b and miR-499 in CAD and analyze its association with the… read more here.
Keywords: 208b mir; cad; mir 208b; mir 499 ... See more keywords
Abstract 133: Exosomal Transfer of Muscle Specific Mir-499 to Endothelial and Endothelial Progenitor Cells Impairs Angiogenesis in Diabetes
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/res.125.suppl_1.133
Abstract: Background: miR-499, a muscle specific-miR, is enhanced in diabetic heart and has been suggested to be a therapeutic target for cardiovascular disease in diabetes. Recent studies provided the evidence that overexpressing miR-499 in ECs inhibits… read more here.
Keywords: muscle; tube formation; mir 499; muscle specific ... See more keywords
Association of a MiR-499 SNP and risk of congenital heart disease in a Chinese population.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2018.64.10.17
Abstract: MicroRNAs (miRNAs) play an important role in heart development. Single nucleotide polymorphisms (SNPs) in miRNAs have been shown to associate with congenital heart disease (CHD). Methionine synthase (MTR), a key enzyme of folate metabolism, is… read more here.
Keywords: risk; chd; mir 499; congenital heart ... See more keywords
Exosomal miR-499a-5p Inhibits Endometrial Cancer Growth and Metastasis via Targeting VAV3
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Management and Research"
DOI: 10.2147/cmar.s283747
Abstract: Background/Aim The current therapeutic strategies for endometrial cancer are limited and unsatisfactory. Accumulating evidence suggest that microRNAs (miRNAs) participate in tumor growth and metastasis. Mesenchymal stem cells (MSCs) derived exosomes (Exos) are considered as better… read more here.
Keywords: growth; exosomal mir; cancer; endometrial cancer ... See more keywords
Expression of miR-208b and miR-499 in Greek Patients with Acute Myocardial Infarction.
Sign Up to like & getrecommendations! Published in 2018 at "In vivo"
DOI: 10.21873/invivo.11239
Abstract: BACKGROUND/AIM Certain microRNAs (miRs) present in human plasma are candidate biomarkers for cardiovascular diseases, including acute myocardial infarction (AMI). We examined the expression of two cardiac-specific miRs (miR-208b and miR-499) in a Greek pathological population.… read more here.
Keywords: 208b mir; mir; myocardial infarction; mir 208b ... See more keywords
Deletion of Neuropeptide Y Attenuates Cardiac Dysfunction and Apoptosis During Acute Myocardial Infarction
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2019.01268
Abstract: Increasing neuropeptide Y (NPY) has been shown to be a risk factor for cardiovascular diseases. However, its role and mechanism in myocardial infarction (MI) have not yet been fully understood. H9c2 cells and neonatal rat… read more here.
Keywords: apoptosis; myocardial infarction; deletion; h2o2 ... See more keywords
[MicroRNA-499 improved septic myocardial dysfunction by regulating myosin heavy chain gene axis].
Sign Up to like & getrecommendations! Published in 2022 at "Zhonghua wei zhong bing ji jiu yi xue"
DOI: 10.3760/cma.j.cn121430-20210706-01012
Abstract: OBJECTIVE To investigate the role and mechanism of microRNA-499 (miR-499) regulating α-myosin heavy chain (α-MHC) and β-myosin heavy chain (β-MHC) gene axis in septic myocardial dysfunction (SMD) and its significance. METHODS Sixty healthy adult male… read more here.
Keywords: pretreatment; mhc; lps group; expression ... See more keywords
Hsa-mir-499 rs3746444 T/C Polymorphism is Associated with Increased Risk of Coronary Artery Disease in a Chinese Population.
Sign Up to like & getrecommendations! Published in 2017 at "Acta Cardiologica Sinica"
DOI: 10.6515/acs20160303a
Abstract: BACKGROUND Coronary artery disease (CAD) is a complex disease resulting from a combination of environmental and genetic factors. We hypothesized that polymorphisms hsa-mir-499 rs3746444 T/C, IRAK1 rs3027898 C/A and RANKL rs7984870 C/G might contribute to… read more here.
Keywords: risk; 499 rs3746444; hsa mir; increased risk ... See more keywords