MiR-501-5p acts as an energetic regulator in head and neck squamous cell carcinoma cells growth and aggressiveness via reducing CLCA4
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DOI: 10.1007/s11033-020-05317-6
Abstract: Recent research have proved that miR-501-5p acted as a potent tumor biomarker in several cancers, excluding head and neck squamous cell carcinoma (HNSCC). The study intends to discover the potential function and mechanism of miR-501-5p… read more here.
Keywords: neck squamous; clca4; mir 501; hnscc ... See more keywords
Loss of schizophrenia-related miR-501-3p in mice impairs sociability and memory by enhancing mGluR5-mediated glutamatergic transmission
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DOI: 10.1126/sciadv.abn7357
Abstract: Schizophrenia is a polygenetic disease, the heterogeneity of which is likely complicated by epigenetic modifications yet to be elucidated. Here, we performed transcriptomic analysis of peripheral blood RNA from monozygotic twins discordant for schizophrenia and… read more here.
Keywords: glutamatergic transmission; loss; sociability memory; mir 501 ... See more keywords
miR‑501‑3p sensitizes glioma cells to cisplatin by targeting MYCN.
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DOI: 10.3892/mmr.2018.9458
Abstract: Cisplatin, a commonly used chemotherapeutic agent for glioma patients, treatment often leads to chemoresistance. Accumulating evidence has demosntrated that microRNA (miRNA/miR) is involved in drug resistance of glioma cells. Nevertheless, the role of miR‑501‑3p in… read more here.
Keywords: mir 501; cells cisplatin; glioma cells; glioma ... See more keywords