MiR-504-3p Has Tumor-Suppressing Activity and Decreases IFITM1 Expression in Non-Small Cell Lung Cancer Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Genetic testing and molecular biomarkers"
DOI: 10.1089/gtmb.2021.0158
Abstract: Objective: To analyze the impact of expression of miR-504-3p on the proliferation, migration, cell cycle transit and rate of apoptosis of NSCLC cells and explore the underlying mechanisms. Methods: The Cancer Genome Atlas (TCGA) database… read more here.
Keywords: cell; expression; lung; nsclc cells ... See more keywords
Upregulation of long non-coding RNA ROR1-AS1 promotes cell growth and migration in bladder cancer by regulation of miR-504
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0227568
Abstract: Background Increasing evidence has suggested that multiple long non-coding RNAs (lncRNAs) act key regulatory functions in the pathogenesis of bladder cancer. This study aimed to determine the expression and clinical significance of lncRNA ROR1 antisense… read more here.
Keywords: cancer; bladder cancer; ror1 as1; mir 504 ... See more keywords
Upregulation of miR-504-3p is associated with favorable prognosis of acute myeloid leukemia and may serve as a tumor suppressor by targeting MTHFD2.
Sign Up to like & getrecommendations! Published in 2019 at "European Review for Medical and Pharmacological Sciences"
DOI: 10.26355/eurrev_201902_17013
Abstract: Objective Deregulated expression of miRNAs contributes to the development of acute myeloid leukemia (AML). miR-504-3p, one of these miRNAs, has been found have upregulated expression in various human malignancies. Our present study aimed to detect… read more here.
Keywords: expression; aml patients; acute myeloid; myeloid leukemia ... See more keywords
MicroRNA-504 modulates osteosarcoma cell chemoresistance to cisplatin by targeting p53
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DOI: 10.3892/ol.2018.9749
Abstract: Chemoresistance implicates the therapeutic value of cisplatin and remains a primary obstacle to its clinical use. MicroRNAs (miRs) negatively modulate the expression of their target genes and are associated with the occurrence and progression of… read more here.
Keywords: chemoresistance; microrna 504; cisplatin; p53 ... See more keywords
miR-504 promotes tumour growth and metastasis in human osteosarcoma by targeting TP53INP1.
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DOI: 10.3892/or.2017.5983
Abstract: An increasing number of studies have demonstrated that microRNAs participate in the development of osteosarcoma by acting as tumour suppressor or tumour-promoting genes. We investigated the role of miR-504 in the growth and metastasis of… read more here.
Keywords: growth metastasis; osteosarcoma; mir 504;