miR‐505 acts as a tumor suppressor in gastric cancer progression through targeting HMGB1
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28082
Abstract: Gastric cancer (GC) is a frequent type of malignant tumor worldwide. GC metastasis results in the majority of clinical treatment failures. MicroRNAs (miRNA) are identified to exhibit crucial roles in GC. Our current study aimed… read more here.
Keywords: hmgb1; mir 505; gastric cancer; mir ... See more keywords
A multiplex sensitive quantification of microRNAs based on competitive PCR
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology and Bioprocess Engineering"
DOI: 10.1007/s12257-016-0364-5
Abstract: MicroRNAs (miRNAs) are endogenous ~22 nt RNAs that play important regulatory roles in animals and plants by targeting mRNAs for cleavage or gene silencing. Although quantitative real-time PCR (qRT-PCR) had been widely used for miRNAs… read more here.
Keywords: mir 505; sensitive quantification; pcr; cpcr ... See more keywords
LncRNA-CTS Promotes Metastasis and Epithelial-to-mesenchymal Transition through regulating miR-505/ZEB2 axis in Cervical Cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2019.09.002
Abstract: Cervical carcinoma (CC) is the second most common cancer in females. In order to improve current anti-metastasis strategies for CC, it is important to improve our understanding of the mechanisms involved in epithelial-to-mesenchymal transition (EMT).… read more here.
Keywords: mir 505; lncrna cts; 505 zeb2; cts mir ... See more keywords
Combination with TMZ and miR-505 inhibits the development of glioblastoma by regulating the WNT7B/Wnt/β-catenin signaling pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.06.030
Abstract: TMZ is the only drug that has improved survival of GBM patients although minimally. However, a number of GBM patients did not respond to TMZ-based chemotherapy. Here, we found that miR-505 inhibited tumorigenesis as a… read more here.
Keywords: combination; mir 505; catenin signaling; signaling pathway ... See more keywords
MicroRNA-505 is involved in the regulation of osteogenic differentiation of MC3T3-E1 cells partially by targeting RUNX2
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Orthopaedic Surgery and Research"
DOI: 10.1186/s13018-020-01645-2
Abstract: Objective Evidence suggests that microRNAs (miRNAs) regulate the expression of genes involved in bone metabolism. This study aimed to investigate the role of miR-505 in the osteogenic differentiation of MC3T3-E1 cells. Methods We performed miRNA… read more here.
Keywords: differentiation mc3t3; mir 505; osteogenic differentiation; mc3t3 cells ... See more keywords
LncRNA MVIH knockdown inhibits the malignancy progression through downregulating miR-505 mediated HMGB1 and CCNE2 in acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2019 at "Translational Cancer Research"
DOI: 10.21037/tcr.2019.10.12
Abstract: Background This study aimed to investigate the regulatory role of long non-coding RNA associated with microvascular invasion in hepatocellular carcinoma (lnc-MVIH) in the progression of acute myeloid leukemia (AML) and the underlying mechanism. Methods Lnc-MVIH… read more here.
Keywords: lnc mvih; mir 505; cell; mvih knockdown ... See more keywords
Long Noncoding RNA LINC00525 Promotes the Aggressive Phenotype of Chordoma Through Acting as a microRNA-505-3p Sponge and Consequently Raising HMGB1 Expression
Sign Up to like & getrecommendations! Published in 2020 at "OncoTargets and therapy"
DOI: 10.2147/ott.s268678
Abstract: Purposes Long intergenic non-protein coding RNA 525 (LINC00525), a long noncoding RNA, has been implicated in the carcinogenesis and progression of many human cancer types. However, the detailed roles of LINC00525 in chordoma and the… read more here.
Keywords: expression; chordoma; linc00525; long noncoding ... See more keywords
LEF-AS1 participates in occurrence of colorectal cancer through adsorbing miR-505 and promoting KIF3B expression.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201911_19429
Abstract: OBJECTIVE To explore the possible role and mechanism of long non-coding ribonucleic acid LEF-AS1 (lncRNA LEF-AS1) in the pathogenesis of colorectal cancer (CRC). PATIENTS AND METHODS The expression levels of LEF-AS1 in 54 CRC tissue… read more here.
Keywords: kif3b; mir 505; lef as1; cell ... See more keywords
MicroRNA-505, Suppressed by Oncogenic Long Non-coding RNA LINC01448, Acts as a Novel Suppressor of Glycolysis and Tumor Progression Through Inhibiting HK2 Expression in Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.625056
Abstract: Background: MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) play vital regulatory roles in pancreatic cancer (PC) initiation and progression. We aimed to explore the biological functions and underlying mechanisms of miR-505-3p (miR-505) in PC. Methods:… read more here.
Keywords: mir 505; long non; expression; suppressor ... See more keywords
Circulating MicroRNA-505 May Serve as a Prognostic Biomarker for Hypertension-Associated Endothelial Dysfunction and Inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.834121
Abstract: Our previous study has reported that the plasma microRNA-505 (miR-505) is elevated in hypertensive patients. However, the pathophysiological significance of miR-505 in hypertension remains to be elucidated. Hypertension is not only a vascular disorder, but… read more here.
Keywords: hypertension; microrna 505; mir 505; endothelial dysfunction ... See more keywords
miR-505-5p alleviates acute rejection of liver transplantation by inhibiting Myd88 and inducing M2 polarizationof Kupffer cells
Sign Up to like & getrecommendations! Published in 2022 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.3724/abbs.2022100
Abstract: The occurrence of acute rejection after liver transplantation seriously impairs the prognosis of patients. miRNA is involved in many physiological and pathological processes of the body, but the mechanism of miRNA action in liver transplantation… read more here.
Keywords: acute rejection; mir 505; transplantation; liver transplantation ... See more keywords