MicroRNA‐506 ameliorates breast cancer‐induced osteolytic bone metastasis via the NFATc‐1 signaling pathway
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DOI: 10.1002/jbt.23156
Abstract: Breast cancer is becoming a common life‐threatening disease, especially in women, along with higher incidence and mortality. MicroRNA (miR)−506 was reported to participate in breast cancer progression, while the role of miR‐506 in breast cancer‐induced… read more here.
Keywords: bone; cancer induced; breast cancer; mir 506 ... See more keywords
Experimental pulmonary fibrosis was suppressed by microRNA-506 through NF-kappa-mediated apoptosis and inflammation
Sign Up to like & getrecommendations! Published in 2019 at "Cell and Tissue Research"
DOI: 10.1007/s00441-019-03054-2
Abstract: Fibrosis in the lungs usually occurs in the initial phase of acute respiratory distress syndrome (ARDS), which exacerbates poor prognosis among patients. MicroRNAs (miRs) have the ability to modulate the expression profiles of many genes,… read more here.
Keywords: lung fibrosis; mir 506; fibrosis; apoptosis ... See more keywords
CircUBAP2 promotes SEMA6D expression to enhance the cisplatin resistance in osteosarcoma through sponging miR-506-3p by activating Wnt/β-catenin signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Histology"
DOI: 10.1007/s10735-020-09883-8
Abstract: The occurrence of chemo-resistance is an essential reason for the high morbidity of osteosarcoma (OS) patients. Circular RNAs (circRNAs) have been involved in the regulation of chemo-resistance in cancers. Semaphorins 6D (SEMA6D) is abnormally expressed… read more here.
Keywords: mir 506; resistance; cisplatin resistance; wnt catenin ... See more keywords
MiR-124 and miR-506 are involved in the decline of protein C in children with extra-hepatic portal vein obstruction
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DOI: 10.1038/s41598-021-91862-4
Abstract: The deficiency of protein C (PROC) can be partly rescued by Rex shunt through restoring portal blood flow in children with extra-hepatic portal venous obstruction (EHPVO). However, the decline of PROC is still found in… read more here.
Keywords: 506 mir; mir 506; mir; proc ... See more keywords
MicroRNA-506-3p inhibits colorectal cancer cell proliferation through targeting enhancer of zeste homologue 2.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1951930
Abstract: A large number of studies have shown that microRNA (miRNA) has an important relationship with the occurrence and development of colorectal cancer (CRC), but its specific molecular mechanism has not been fully elucidated. This study… read more here.
Keywords: cell proliferation; mir 506; colorectal cancer; crc ... See more keywords
Hepatic stellate cell‐released CXCL1 aggravates HCC malignant behaviors through the MIR4435‐2HG/miR‐506‐3p/TGFB1 axis
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DOI: 10.1111/cas.15605
Abstract: Hepatic stellate cell (HSC) activation is a critical event in the development of hepatic fibrosis and hepatocellular carcinoma (HCC). By the release of soluble cytokines, chemokines, and chemotaxis, HSCs affect HCC cell phenotypes through a… read more here.
Keywords: mir 506; hcc cell; hcc; mir4435 2hg ... See more keywords
circSYPL1 Promotes the Proliferation and Metastasis of Hepatocellular Carcinoma via the Upregulation of EZH2 Expression by Competing with hsa-miR-506-3p
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/2659563
Abstract: Objective Circular RNAs (circRNAs) and microRNAs are crucial for progressing of hepatocellular carcinoma (HCC). Nonetheless, the function or mechanisms of a newly discovered circRNA, circSYPL1, as well as miR-506-3p, in the progression of HCC are… read more here.
Keywords: mir 506; ezh2 expression; hcc; circsypl1 ... See more keywords
Abstract 3759: Impact of individual and combined deregulation of miR-143 and miR-506 on cytokinetic and morphometric parameters in A549 lung cancer cells
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DOI: 10.1158/1538-7445.am2023-3759
Abstract: Lung cancer (LC) is among the leading causes of death from malignancies worldwide. miRNAs (miRs), small noncoding RNAs capable of regulating gene expression through the cell’s RNAi mechanism, have emerged as promising molecules for cancer… read more here.
Keywords: cell; 143 mir; mir 143; mir 506 ... See more keywords
miR-506-3p Relieves Neuropathic Pain following Brachial Plexus Avulsion via Mitigating Microglial Activation through Targeting the CCL2-CCR2 Axis
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DOI: 10.1159/000528450
Abstract: Neuroinflammation results in neuropathic pain (NP) following brachial plexus avulsion (BPA). This research was designed for investigating the function of miR-506-3p in BPA-induced NP. A total brachial plexus root avulsion model was produced in adult… read more here.
Keywords: mir 506; ccl2 ccr2; brachial plexus; avulsion ... See more keywords
Circ_100565 promotes proliferation, migration and invasion in non-small cell lung cancer through upregulating HMGA2 via sponging miR-506-3p
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DOI: 10.1186/s12935-020-01241-8
Abstract: Background Circular RNAs (circRNAs) play a vital role in the development of various cancers. Circ_100565 was found to be a highly expressed circRNA in non-small cell lung cancer (NSCLC) tissues screened by microarray profiles of… read more here.
Keywords: nsclc; circ 100565; mir 506; cell ... See more keywords
FGD5-AS1 facilitates the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells via targeting the miR-506-3p/BMP7 axis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Orthopaedic Surgery and Research"
DOI: 10.1186/s13018-021-02694-x
Abstract: Background Osteoporosis is a systemic disease characterized by impaired bone formation, increased bone resorption, and brittle bone fractures. The osteogenic differentiation of human bone marrow-derived mesenchymal stem cells (hBMSCs) is considered to be a vital… read more here.
Keywords: mir 506; bone; fgd5 as1; osteogenic differentiation ... See more keywords