MiR-509-5p suppresses the proliferation, migration, and invasion of non-small cell lung cancer by targeting YWHAG.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2016.11.136
Abstract: Dysregulation of microRNAs (miRNAs) expression is prevalent in human malignancy development and progression. As previously reported, miR-509-5p has been identified as a tumor suppressor in various cancers, but its role and functional mechanism in non-small… read more here.
Keywords: proliferation migration; mir 509; lung cancer; proliferation ... See more keywords
miR-509-5p anti-infection response for mycoplasma pneumonia in sheep by targeting NF-κB pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2021.110275
Abstract: MicroRNAs play a key role in Mannan-binding lectin-mediated resistance to Mycoplasma ovipneumoniae pneumonia, by regulating the translation of mRNAs of target genes, thereby regulating the immune response. Additionally, TRAF6 is a key molecule in Toll-like… read more here.
Keywords: pneumonia sheep; mir 509; response; significantly regulated ... See more keywords
miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-04191-w
Abstract: The epithelial-mesenchymal transition (EMT) contributes to various processes in cancer progression, such as metastasis and drug resistance. Since we have already established a cell-based reporter system for identifying EMT-suppressive microRNAs (miRNAs) in the pancreatic cancer… read more here.
Keywords: mir 1243; mir 509; mir; pancreatic cancer ... See more keywords
LncRNA HOXA-AS2 promotes the progression of prostate cancer via targeting miR-509-3p/PBX3 axis
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20193287
Abstract: Abstract Long non-coding RNAs (lncRNAs) act as crucial modulators during the development of diverse cancers. Although various types of lncRNAs in prostate cancer (PCa) have been explored, quantities of lncRNAs still wait to be exploited.… read more here.
Keywords: expression; hoxa as2; mir 509; pbx3 ... See more keywords
Human pulmonary artery smooth muscle cell dysfunction is regulated by miR-509-5p in hypoxic environment
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2044147
Abstract: ABSTRACT Reportedly, dysfunction of human pulmonary arterial smooth muscle cells (PASMCs) is associated with the pathogenesis of pulmonary arterial hypertension (PAH). Herein, the role of miR-509-5p in hypoxia-induced PASMCs and the underlying mechanism were explored.… read more here.
Keywords: regulated mir; human pulmonary; mir 509; dnmt1 ... See more keywords
MALAT1 Promotes the Proliferation and Metastasis of Osteosarcoma Cells By Activating the Rac1/JNK Pathway Via Targeting MiR-509.
Sign Up to like & getrecommendations! Published in 2018 at "Oncology research"
DOI: 10.3727/096504017x14957939026111
Abstract: Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a long noncoding RNA (lncRNA) that contributes to the initiation and development of many solid tumors, including osteosarcoma (OS). In this study, we showed that MALAT1 was increased… read more here.
Keywords: rac1 jnk; mir 509; malat1; metastasis ... See more keywords
MicroRNA-509 acts as a tumor suppressor in tongue squamous cell carcinoma by targeting epidermal growth factor receptor
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2017.7531
Abstract: Tongue squamous cell carcinoma (TSCC) is the most frequent type of oral carcinoma, and is characterized by high metastatic and growth capabilities. Previous studies have demonstrated that aberrantly expressed cancer-associated microRNAs (miRs) may be associated… read more here.
Keywords: growth; carcinoma; mir 509; tscc ... See more keywords
Long noncoding RNA CBR3 antisense RNA 1 promotes the aggressive phenotypes of non-small-cell lung cancer by sponging microRNA-509-3p and competitively upregulating HDAC9 expression
Sign Up to like & getrecommendations! Published in 2020 at "Oncology Reports"
DOI: 10.3892/or.2020.7719
Abstract: Long noncoding RNA CBR3 antisense RNA 1 (CBR3-AS1) plays significant roles in the initiation and progression of osteosarcoma. The aim of the present study was to investigate the involvement of CBR3-AS1 in the development of… read more here.
Keywords: rna cbr3; mir 509; cbr3 as1; expression ... See more keywords