Articles with "mir 512" as a keyword



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Circular RNA hsa_circ_0004277 contributes to malignant phenotype of colorectal cancer by sponging miR-512-5p to upregulate the expression of PTMA.

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Published in 2020 at "Journal of cellular physiology"

DOI: 10.1002/jcp.29484

Abstract: In recent years, extensive reports have been published concerning the molecular mechanism underlying the occurrence and progression of colorectal cancer. Circular RNAs (circRNAs) have been identified as important modulators in the biological processes of colorectal… read more here.

Keywords: expression; mir 512; colorectal cancer; circ 0004277 ... See more keywords
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Long non-coding ribonucleic acid AFAP1-AS1 promotes chondrocyte proliferation via the miR-512-3p/matrix metallopeptidase 13 (MMP-13) axis

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2031390

Abstract: ABSTRACT Long-chain non-coding RNAs are reported to be involved in cartilage damage. However, less research on the role of actin filament-associated protein 1 antisense RNA 1 (AFAP1-AS1) in osteoarthritis. To investigate AFAP1-AS1 function in osteoarthritis… read more here.

Keywords: afap1 as1; mir 512; chondrocyte proliferation; expression ... See more keywords
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Hsa_circ_0005576 promotes the osimertinib resistance through miR-512-5p/IGF1R axis in lung adenocarcinoma cells.

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Published in 2021 at "Cancer science"

DOI: 10.1111/cas.15177

Abstract: Osimertinib is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) for lung adenocarcinoma (LUAD) harboring activating mutations, but patients ultimately develop acquired resistance. Circular RNAs are involved in EGFR-TKI resistance, while the role… read more here.

Keywords: luad; mir 512; osimertinib resistance; hsa circ ... See more keywords
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Decorin–induced, preeclampsia-associated microRNA-512-3p restrains extravillous trophoblast functions by targeting USF2/PPP3R1 axis

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Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.1014672

Abstract: Decorin (DCN) is a leucine-rich proteoglycan produced by chorionic villus mesenchymal cells anddecidual cells during human pregnancy. Studies from our laboratory demonstrated that decidua-derived DCN restrains multiple trophoblast functions including proliferation, migration, invasion andendovascular differentiation,… read more here.

Keywords: mir 512; decorin; trophoblast functions; dcn ... See more keywords
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The Similar Effects of miR-512-3p and miR-519a-2-5p on the Promotion of Hepatocellular Carcinoma: Different Tunes Sung With Equal Skill

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Published in 2020 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2020.01244

Abstract: Although the therapeutic methods of hepatocellular carcinoma (HCC) have made great advances, the current situation is that HCC is the common malignancy. Our previous bioinformatic study presented that two members of C19MC (mir-512-1 and mir-519a-2)… read more here.

Keywords: hepatocellular carcinoma; mir 519a; similar effects; mir 512 ... See more keywords
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SNHG8 Promotes the Progression of Epstein–Barr Virus-Associated Gastric Cancer via Sponging miR-512-5p and Targeting TRIM28

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Published in 2021 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2021.734694

Abstract: SNHG8, a family member of small nucleolar RNA host genes (SNHG), has been reported to act as an oncogene in gastric carcinoma (GC). However, its biological function in Epstein–Barr virus (EBV)-associated gastric cancer (EBVaGC) remains… read more here.

Keywords: snhg8; trim28; mir 512; expression ... See more keywords
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Depletion of circ_0001313 suppresses the carcinogenesis of laryngeal carcinoma through miR 512 5p/HMGA1 pathway

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Published in 2023 at "Tropical Journal of Pharmaceutical Research"

DOI: 10.4314/tjpr.v22i3.12

Abstract: Purpose: To probe the influence of circ_0001313 on the occurrence and development of laryngeal carcinoma and the potential molecular mechanism. Methods: 27 cases of laryngeal carcinoma attending health facility from January 2017 to September 2020… read more here.

Keywords: laryngeal carcinoma; circ 0001313; mir 512; 512 hmga1 ... See more keywords