CircRNA OXCT1 promotes the malignant progression and glutamine metabolism of non-small cell lung cancer by absorbing miR-516b-5p and upregulating SLC1A5
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2071565
Abstract: ABSTRACT Previous study has demonstrated the high expression of circular RNA 3-oxoacid CoA-transferase 1 (circ-OXCT1) in lung adenocarcinoma tumor tissues. However, the role and possible mechanism of circ-OXCT1 in non-small cell lung cancer (NSCLC) progression… read more here.
Keywords: cell; circ oxct1; slc1a5; mir 516b ... See more keywords
LncRNA ARAP1-AS1 targets miR-516b-5p/PDE5A axis to facilitate the progression of thyroid cancer
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001438
Abstract: Thyroid cancer (TC) remains a prevalent public health concern. To further study the molecular mechanism of TC development, we explored the regulatory mechanism and function of lncRNA ARAP1-AS1 in TC progression. The verification of ARAP1-AS1,… read more here.
Keywords: pde5a; cancer; arap1 as1; mir 516b ... See more keywords
MiRNA-516b inhibits ameloblastoma cell proliferation and invasion by regulating MYCBP/c-myc/RECK/MMP pathway
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DOI: 10.21037/15370
Abstract: Background: Ameloblastoma (AM) is a frequent odontogenic tumor, which is associated with high risk of recurrence. Previous studies have reported dysregulation of miRNA-516b (miR-516bis dysregulated in some malignancies); however, its biological function in AM is… read more here.
Keywords: invasion; cell proliferation; mir 516b;
circAFF1 Aggravates Vascular Endothelial Cell Dysfunction Mediated by miR-516b/SAV1/YAP1 Axis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.00899
Abstract: Pathological vascular endothelial damage caused by hypoxia is the basis of many vascular-related diseases. However, the role of circular RNA in hypoxic vascular injury is still poorly understood. Here, we found that hypoxia induced AFF1… read more here.
Keywords: vascular endothelial; dysfunction; circaff1; sav1 yap1 ... See more keywords