Targeting of ΔNp63α by miR‐522 promotes the migration of breast epithelial cells
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13072
Abstract: The TP63 gene, which encodes the p63 protein, is involved in multiple biological processes, including embryonic development and tumorigenesis. ΔNp63α, the predominant isoform of p63 in epithelial cells, acts as an oncogene in early‐stage tumors,… read more here.
Keywords: epithelial cells; breast epithelial; mir; targeting np63 ... See more keywords
Overexpression of LINC00261 inhibits non–small cell lung cancer cells progression by interacting with miR‐522‐3p and suppressing Wnt signaling
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DOI: 10.1002/jcb.29149
Abstract: Long noncoding RNA LINC00261 has been experimentally validated to function as a tumor suppressor in several cancers, but its pathological role and functional mechanism in non–small cell lung cancer (NSCLC) are largely unclear. In this… read more here.
Keywords: overexpression; wnt signaling; linc00261; cancer ... See more keywords
rs6426881 in the 3'-UTR of PBX1 is involved in breast and gastric cancers via altering the binding potential of miR-522-3p.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06756-5
Abstract: BACKGROUND Breast and gastric cancers are the most important diseases that lead to cancer death and social healthcare challenge. Overexpression of PBX1, a proto-oncogene, is correlated with the progression and metastasis of various cancers. For the… read more here.
Keywords: breast gastric; gastric cancers; pbx1; cancer ... See more keywords
MiR-522-3p Targets Transcription Factor 4 to Overcome Cisplatin Resistance of Gastric Cells
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DOI: 10.1155/2022/6082373
Abstract: Gastric cancer (GC) is a malignancy originating from gastric epithelial tissue. Chemoresistance to cisplatin (DDP) often leads to chemotherapy failure in GC. Previously, miR-522 was found to be associated with chemoresistance in GC cells. Thus,… read more here.
Keywords: cell; mir 522; tcf4; ddp ... See more keywords
Long non-coding RNA LINC00238 suppresses the malignant phenotype of liver cancer by sponging miR-522
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DOI: 10.3892/mmr.2022.12587
Abstract: Long non-coding RNAs can regulate the malignant tumor phenotype either as tumor suppressors or oncogenes. The present study investigated the underlying mechanism of LINC00238 in liver cancer. LINC00238 was identified as a downregulated molecule in… read more here.
Keywords: liver cancer; phenotype; mir 522; tumor ... See more keywords