Articles with "mir 524" as a keyword



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Long noncoding RNA TUG1 regulates the development of oral squamous cell carcinoma through sponging miR‐524‐5p to mediate DLX1 expression as a competitive endogenous RNA

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Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.28620

Abstract: Long noncoding RNA (lncRNA) exerts a potential regulatory role in tumorigenesis. LncRNA TUG1 expression remains high in oral squamous cell carcinoma (OSCC) tissues. However, its biological mechanism in OSCC remains unknown. In this study, TUG1… read more here.

Keywords: tug1; rna; mir 524; expression ... See more keywords
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Exosome-transmitted circVMP1 facilitates the progression and cisplatin resistance of non-small cell lung cancer by targeting miR-524-5p-METTL3/SOX2 axis.

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Published in 2022 at "Drug delivery"

DOI: 10.1080/10717544.2022.2057617

Abstract: BACKGROUND Circular RNAs (circRNAs) play important regulatory roles in multiple human malignancies, including non-small cell lung cancer (NSCLC). Here, we explored the role of circRNA vacuole membrane protein 1 (circVMP1) in NSCLC progression and cisplatin… read more here.

Keywords: ddp resistance; circvmp1; resistance; mir 524 ... See more keywords
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Knockdown of lncRNA TUG1 alleviates diabetic retinal vascular dysfunction through regulating miR-524-5p/FGFR2

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2075306

Abstract: ABSTRACT Long noncoding RNAs (LncRNAs) have been shown to play critical roles in the development of diabetic retinopathy (DR), which is often regarded as the most frequent cause of visual loss in the world. This… read more here.

Keywords: mir 524; lncrna tug1; tug1; retinal vascular ... See more keywords
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Long non-coding RNA nuclear enriched abundant transcript 1 (NEAT1) modulates inhibitor of DNA binding 1 (ID1) to facilitate papillary thyroid carcinoma development by sponging microRNA-524-5p

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2076498

Abstract: ABSTRACT Long non-coding RNA (lncRNA) nuclear-enriched abundant transcript 1 (NEAT1) exerts a pro-oncogenic role in several cancers, whereas its underlying regulatory mechanism in papillary thyroid carcinoma (PTC) progression remains unknown. This research mainly explored the… read more here.

Keywords: long non; mir 524; ptc; development ... See more keywords
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EGFR-AS1 Promotes Nonsmall Cell Lung Cancer (NSCLC) Progression via Downregulating the miR-524-5p/DRAM1 Axis and Inhibiting Autophagic Lysosomal Degradation

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Published in 2022 at "Journal of Oncology"

DOI: 10.1155/2022/4402536

Abstract: Nonsmall cell lung cancer (NSCLC) accounts for the majority of lung cancers. Studies have revealed the regulatory role of lncRNAs in cancer pathogenesis and their potential use as diagnostic and prognostic biomarkers. The epidermal growth… read more here.

Keywords: lung cancer; dram1; mir 524; egfr as1 ... See more keywords
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EZH2 alteration driven by microRNA-524-5p and microRNA-324-5p promotes cell proliferation and temozolomide resistance in glioma

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.21996

Abstract: Recent data have been shown that EZH2 is a critical oncogene via the repression of tumor suppressor genes in human cancers. In our study, we performed a genome-wide miRNA screen with a bioinformatics analysis to… read more here.

Keywords: glioma; cell proliferation; mir 524; 524 mir ... See more keywords
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LncRNA TTN-AS1 Regulates miR-524-5p and RRM2 to Promote Breast Cancer Progression

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Published in 2020 at "OncoTargets and therapy"

DOI: 10.2147/ott.s243482

Abstract: Background Recent studies suggest many long non-coding RNAs (lncRNAs) are crucial oncogenes or tumor suppressors. This study intended to investigate the biological function and mechanism of lncRNA TTN antisense RNA 1 (TTN-AS1) in the progression… read more here.

Keywords: expression; mir 524; rrm2; ttn ... See more keywords
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MiR-524 inhibits cell proliferation and induces cell apoptosis in thyroid cancer via targeting SPAG9.

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Published in 2018 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_201806_15265

Abstract: OBJECTIVE To investigate the effect of miR-524 on the proliferation of thyroid cancer and its underlying mechanism. PATIENTS AND METHODS MiR-524 expression levels in thyroid cancer samples and para-cancer tissues were tested by quantitative Real-time… read more here.

Keywords: apoptosis thyroid; mir 524; proliferation; thyroid cancer ... See more keywords