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   Articles with "mir 532" as a keyword



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Bone marrow mesenchymal stem cells‐derived exosomes mediate nuclear receptor coactivator‐3 expression in osteoblasts by delivering miR‐532‐5p to influence osteonecrosis of the femoral head development

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recommendations! Published in 2022 at "Cell Biology International"

DOI: 10.1002/cbin.11902

Abstract: Exosomes (Exo) originated from bone marrow mesenchymal stem cells (BMSCs) have therapeutic impacts on osteonecrosis of the femoral head (ONFH), and microRNA (miR)‐532‐5p has been confirmed to participate in ONFH progression. In the research, it… read more here.

Keywords: marrow mesenchymal; bone marrow; delivering mir; mesenchymal stem ... See more keywords
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LncRNA TSIX aggravates spinal cord injury by regulating the PI3K/AKT pathway via the miR-532-3p/DDOST axis.

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recommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"

DOI: 10.1002/jbt.23384

Abstract: Long noncoding RNA (lncRNA)-X-inactive-specific transcript (TSIX) expression is upregulated in spinal cord tissues following spinal cord injury (SCI). However, the role of lncRNA-TSIX in SCI remains elusive. SCI animal model was established using C57BL/6 mice.… read more here.

Keywords: ddost; lncrna tsix; mir 532; spinal cord ... See more keywords
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A genetic variant located in the miR-532-5p-binding site of TGFBR1 is associated with the colorectal cancer risk

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recommendations! Published in 2018 at "Journal of Gastroenterology"

DOI: 10.1007/s00535-018-1490-y

Abstract: BackgroundGenome-wide association studies have identified genes in the transforming growth factor-β (TGFβ) signaling pathway that are responsible for regulating carcinogenesis.MethodsWe searched for single-nucleotide polymorphisms (SNPs) located within 3′-untranslated regions (3′-UTRs) that might affect the ability… read more here.

Keywords: tgfbr1; colorectal cancer; cancer risk; mir 532 ... See more keywords
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MicroRNA-532 exerts oncogenic functions in t(4;14) multiple myeloma by targeting CAMK2N1

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recommendations! Published in 2019 at "Human Cell"

DOI: 10.1007/s13577-019-00276-y

Abstract: Multiple myeloma (MM) is a plasma cell neoplasm which is characterized by widespread genetic heterogeneity. The MMs with t(4;14) translocation exhibit poor outcomes. However, the mechanism underlying has not been well dissected. Our study aimed… read more here.

Keywords: targeting camk2n1; multiple myeloma; 532 exerts; mir 532 ... See more keywords
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MiR-532-5p alleviates hypoxia-induced cardiomyocyte apoptosis by targeting PDCD4.

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recommendations! Published in 2018 at "Gene"

DOI: 10.1016/j.gene.2018.06.087

Abstract: MicroRNAs (miRNAs) are a class of endogenous non-coding RNAs involved in regulating various biological processes at the post-transcription level. Accumulating evidence suggests that hypoxia caused by acute myocardial infarction induces cardiomyocyte damage including apoptosis. Previous… read more here.

Keywords: apoptosis; h9c2 cells; hypoxia induced; mir 532 ... See more keywords
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MiR-532-5p suppresses renal cancer cell proliferation by disrupting the ETS1-mediated positive feedback loop with the KRAS-NAP1L1/P-ERK axis

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recommendations! Published in 2018 at "British Journal of Cancer"

DOI: 10.1038/s41416-018-0196-5

Abstract: BackgroundDespite the fact that miRNAs play pivotal roles in various human malignancies, their molecular mechanisms influencing RCC are poorly understood.MethodsThe expression of miRNAs from RCC and paired normal renal specimens was analysed by a combined… read more here.

Keywords: kras nap1l1; cell proliferation; nap1l1 erk; mir 532 ... See more keywords
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Circular RNA circFGD4 suppresses gastric cancer progression via modulating miR-532-3p/APC/β-catenin signalling pathway.

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recommendations! Published in 2020 at "Clinical science"

DOI: 10.1042/cs20191043

Abstract: BACKGROUND Mounting evidence has displayed critical roles of circular RNAs (circRNAs) in multiple cancers. The underlying mechanisms by which circFGD4 contributed to gastric cancer (GC) are still unclear. METHODS The levels and clinical values of… read more here.

Keywords: catenin signalling; gastric cancer; mir 532; apc catenin ... See more keywords
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LncRNA PVT1 inhibits endothelial cells apoptosis in coronary heart disease through regulating MAPK1 expression via miR-532-3p.

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recommendations! Published in 2023 at "Acta cardiologica"

DOI: 10.1080/00015385.2023.2209448

Abstract: Background: Coronary atherosclerotic heart disease (CAD) is an inflammatory vascular disease caused by atherosclerosis. Long non-coding RNAs are involved in the pathophysiological process of coronary heart disease. Here we investigated the regulatory effects of lncRNA… read more here.

Keywords: mapk1 expression; pvt1; heart disease; mir 532 ... See more keywords
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Circ_0007841 knockdown confers cisplatin sensitivity to ovarian cancer cells by down-regulation of NFIB expression in a miR-532-5p-dependent manner

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recommendations! Published in 2022 at "Journal of Chemotherapy"

DOI: 10.1080/1120009x.2022.2056995

Abstract: ABSTRACT Cisplatin (DDP) is first-line management for ovarian cancer (OC). Previous data have suggested that circular RNA_0007841 (circ_0007841) regulates OC progression; however, there is no data on its role in the sensitivity of OC cells… read more here.

Keywords: circ 0007841; ddp resistant; sensitivity; mir 532 ... See more keywords
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CircFAM53B promotes the proliferation and metastasis of glioma through activating the c-MET/PI3K/AKT pathway via sponging miR-532-3p

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recommendations! Published in 2022 at "Cell Cycle"

DOI: 10.1080/15384101.2021.2014738

Abstract: ABSTRACT Increasing evidence reveals that circular RNAs (circRNAs) regulate multiple biological functions in glioma. Previously, several reports have illustrated that circFAM53B contributes to cancer development. However, the functions and mechanisms of circFAM53B in glioma remain… read more here.

Keywords: pi3k akt; proliferation metastasis; circfam53b; glioma ... See more keywords
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Downregulation of autophagy-related circular RNA (ACR) is correlated with poor survival of patients with chronic heart failure

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2059862

Abstract: ABSTRACT Autophagy‐related circular RNA (ACR) has been reported to protect myocardial tissues from injury and participate in chronic heart failure (CHF), while its role in CHF is unknown. This study aimed to study the role… read more here.

Keywords: acr; circular rna; related circular; rna acr ... See more keywords