Circ_0004104 Accelerates the Progression of Gastric Cancer by Regulating the miR-539-3p/RNF2 Axis
Sign Up to like & getrecommendations! Published in 2021 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06802-5
Abstract: Circular RNA (circRNA) has been shown to be closely associated with cancer progression, including gastric cancer (GC). However, the function of circ_0004104 in GC progression has not been clarified. The purpose of this study was… read more here.
Keywords: circ 0004104; rnf2; mir 539; cancer ... See more keywords
Recombinant water stress protein 1 (Re-WSP1) suppresses colon cancer cell growth through the miR-539/β-catenin signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06549-w
Abstract: BACKGROUND Nostoc commune Vauch. is a nitrogen-fixing blue-green algae that expresses a large number of active molecules with medicinal properties. Our previous study found that a water stress protein (WSP1) from N. commune and its… read more here.
Keywords: wsp1; catenin; colon cancer; mir 539 ... See more keywords
miR-539 Targeting SNAI2 Regulates MMP9 Signaling Pathway and Affects Blood-Brain Barrier Permeability in Cerebrovascular Occlusive Diseases: A Study Based on Head and Neck Ultrasound and CTA
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Healthcare Engineering"
DOI: 10.1155/2021/5699025
Abstract: This study aimed to explore the expression level of miR-539 in the blood-brain barrier permeability induced by cerebrovascular occlusion and its mediated mechanism. Altogether, 48 patients with cerebral vascular occlusion lesions from March 2018 to… read more here.
Keywords: permeability; mir 539; blood brain; brain barrier ... See more keywords
LncRNA-XIST Promotes Proliferation and Migration in ox-LDL Stimulated Vascular Smooth Muscle Cells through miR-539-5p/SPP1 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/9911982
Abstract: Long noncoding RNAs (lncRNAs) are untranslated transcripts greater than 200 nucleotides in length. Despite not being translated, they play a role in the regulation of transcription, translation, and other cellular processes and have been identified… read more here.
Keywords: proliferation migration; vascular smooth; ldl stimulated; mir 539 ... See more keywords
MiR-539-3p inhibited chondrogenic differentiation in human adipose stem cells by targeting Sox9
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Orthopaedic Surgery and Research"
DOI: 10.1186/s13018-022-03053-0
Abstract: Background Mesenchymal stem cells (MSCs) have emerged as the attractive candidates for cell therapy for cartilage repair in clinical therapy of osteoarthritis (OA). MiR-539-3p was reported to differentially express during chondrogenic differentiation of adipose stem… read more here.
Keywords: mir 539; differentiation hascs; stem cells; chondrogenic differentiation ... See more keywords
lncRNA CCAT2 Protects Against Cardiomyocyte Injury After Myocardial Ischemia/Reperfusion by Regulating BMI1 Expression.
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DOI: 10.1536/ihj.23-569
Abstract: Myocardial ischemia/reperfusion (I/R) decreases cardiac function and efficiency. Accumulating evidence suggests that long noncoding RNAs (lncRNAs) have been linked to the cellular processes of myocardial I/R injury. The present investigation elucidated the function of lncRNA… read more here.
Keywords: myocardial ischemia; ischemia reperfusion; cardiomyocyte injury; mir 539 ... See more keywords
Long Noncoding RNA LINC00460 Modulates MMP-9 to Promote Cell Proliferation, Invasion and Apoptosis by Targeting miR-539 in Papillary Thyroid Cancer
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DOI: 10.2147/cmar.s222085
Abstract: Background Increasing evidence shows that Long non-coding RNAs (lncRNAs) involve in the development and progression processes of various cancers, including papillary thyroid cancer (PTC). In this study, we focused on the regulation function of lncRNA… read more here.
Keywords: cell proliferation; mir 539; invasion; apoptosis ... See more keywords
LINC00460 promotes proliferation and inhibits apoptosis of non-small cell lung cancer cells through targeted regulation of miR-539.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202006_21663
Abstract: OBJECTIVE To explore the effects of long intergenic non-coding ribonucleic acid 00460 (LINC00460) on the proliferation and apoptosis of non-small cell lung cancer (NSCLC) cells. MATERIALS AND METHODS In this study, the expression of LINC00460… read more here.
Keywords: apoptosis; proliferation; mir 539; linc00460 ... See more keywords
MiR-539-3p Alleviates Apoptosis and Extracellular Matrix Degradation in Chondrocytes of Childhood-Onset Osteoarthritis by Targeting RUNX2.
Sign Up to like & getrecommendations! Published in 2024 at "Physiological research"
DOI: 10.33549/physiolres.935291
Abstract: Recent research has identified that miR-539-3p impedes chondrogenic differentiation, yet its specific role and underlying mechanisms in childhood-onset osteoarthritis (OA) remain unclear. This study found that miR-539-3p levels were considerably lower in cartilage samples derived… read more here.
Keywords: matrix; degradation chondrocytes; targeting runx2; mir 539 ... See more keywords
miR-539-5p targets BMP2 to regulate Treg activation in B-cell acute lymphoblastic leukemia through TGF-β/Smads/MAPK
Sign Up to like & getrecommendations! Published in 2024 at "Experimental Biology and Medicine"
DOI: 10.3389/ebm.2024.10111
Abstract: MicroRNAs (mRNAs) were believed to play an important role in cancers, and this study aimed to explore the mechanism of miRNA regulating Treg in B-cell acute lymphoblastic leukemia (B-ALL). Firstly, the differentially expressed miRNAs and… read more here.
Keywords: treg activation; mir 539; activation; smads mapk ... See more keywords
MicroRNA-539-5p-Loaded PLGA Nanoparticles Grafted with iRGD as a Targeting Treatment for Choroidal Neovascularization
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14020243
Abstract: Choroidal neovascularization (CNV) is a major cause of visual impairment that results from excessive growth of blood vessels in the eye’s choroid. The limited clinical efficacy of the current therapy for this condition requires the… read more here.
Keywords: irgd; plga; plga nps; mir 539 ... See more keywords