Circ_0004104 Accelerates the Progression of Gastric Cancer by Regulating the miR-539-3p/RNF2 Axis
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DOI: 10.1007/s10620-020-06802-5
Abstract: Circular RNA (circRNA) has been shown to be closely associated with cancer progression, including gastric cancer (GC). However, the function of circ_0004104 in GC progression has not been clarified. The purpose of this study was… read more here.
Keywords: circ 0004104; rnf2; mir 539; cancer ... See more keywords
Recombinant water stress protein 1 (Re-WSP1) suppresses colon cancer cell growth through the miR-539/β-catenin signaling pathway.
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DOI: 10.1007/s11033-021-06549-w
Abstract: BACKGROUND Nostoc commune Vauch. is a nitrogen-fixing blue-green algae that expresses a large number of active molecules with medicinal properties. Our previous study found that a water stress protein (WSP1) from N. commune and its… read more here.
Keywords: wsp1; catenin; colon cancer; mir 539 ... See more keywords
miR-539 Targeting SNAI2 Regulates MMP9 Signaling Pathway and Affects Blood-Brain Barrier Permeability in Cerebrovascular Occlusive Diseases: A Study Based on Head and Neck Ultrasound and CTA
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DOI: 10.1155/2021/5699025
Abstract: This study aimed to explore the expression level of miR-539 in the blood-brain barrier permeability induced by cerebrovascular occlusion and its mediated mechanism. Altogether, 48 patients with cerebral vascular occlusion lesions from March 2018 to… read more here.
Keywords: permeability; mir 539; blood brain; brain barrier ... See more keywords
LncRNA-XIST Promotes Proliferation and Migration in ox-LDL Stimulated Vascular Smooth Muscle Cells through miR-539-5p/SPP1 Axis
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DOI: 10.1155/2022/9911982
Abstract: Long noncoding RNAs (lncRNAs) are untranslated transcripts greater than 200 nucleotides in length. Despite not being translated, they play a role in the regulation of transcription, translation, and other cellular processes and have been identified… read more here.
Keywords: proliferation migration; vascular smooth; ldl stimulated; mir 539 ... See more keywords
MiR-539-3p inhibited chondrogenic differentiation in human adipose stem cells by targeting Sox9
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DOI: 10.1186/s13018-022-03053-0
Abstract: Background Mesenchymal stem cells (MSCs) have emerged as the attractive candidates for cell therapy for cartilage repair in clinical therapy of osteoarthritis (OA). MiR-539-3p was reported to differentially express during chondrogenic differentiation of adipose stem… read more here.
Keywords: mir 539; differentiation hascs; stem cells; chondrogenic differentiation ... See more keywords
Long Noncoding RNA LINC00460 Modulates MMP-9 to Promote Cell Proliferation, Invasion and Apoptosis by Targeting miR-539 in Papillary Thyroid Cancer
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DOI: 10.2147/cmar.s222085
Abstract: Background Increasing evidence shows that Long non-coding RNAs (lncRNAs) involve in the development and progression processes of various cancers, including papillary thyroid cancer (PTC). In this study, we focused on the regulation function of lncRNA… read more here.
Keywords: cell proliferation; mir 539; invasion; apoptosis ... See more keywords
LINC00460 promotes proliferation and inhibits apoptosis of non-small cell lung cancer cells through targeted regulation of miR-539.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202006_21663
Abstract: OBJECTIVE To explore the effects of long intergenic non-coding ribonucleic acid 00460 (LINC00460) on the proliferation and apoptosis of non-small cell lung cancer (NSCLC) cells. MATERIALS AND METHODS In this study, the expression of LINC00460… read more here.
Keywords: apoptosis; proliferation; mir 539; linc00460 ... See more keywords
MicroRNA-539-5p-Loaded PLGA Nanoparticles Grafted with iRGD as a Targeting Treatment for Choroidal Neovascularization
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DOI: 10.3390/pharmaceutics14020243
Abstract: Choroidal neovascularization (CNV) is a major cause of visual impairment that results from excessive growth of blood vessels in the eye’s choroid. The limited clinical efficacy of the current therapy for this condition requires the… read more here.
Keywords: irgd; plga; plga nps; mir 539 ... See more keywords
MicroRNA‑539 inhibits the proliferation and invasion of bladder cancer cells by regulating IGF‑1R.
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DOI: 10.3892/mmr.2018.8497
Abstract: Bladder cancer is the most frequent malignancy of the urinary tract and the seventh most common cancer worldwide. The abnormal expression of microRNAs has been frequently observed in various types of human cancers, including bladder… read more here.
Keywords: cancer; bladder cancer; proliferation invasion; mir 539 ... See more keywords
MicroRNA‑539 inhibits cell proliferation, colony formation and invasion in pancreatic ductal adenocarcinoma by directly targeting IGF‑1R.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular medicine reports"
DOI: 10.3892/mmr.2018.9109
Abstract: MicroRNAs (miRNAs) possess oncogenic and tumour‑suppressive roles in the carcinogenesis and progression of pancreatic ductal adenocarcinoma (PDAC) by regulating the expression of numerous cancer‑related genes. Thus, the investigation on the expression and roles of miRNAs… read more here.
Keywords: pdac; mir 539; igf; expression ... See more keywords