Articles with "mir 542" as a keyword



miR‐542‐5p targets GREM1 to affect the progression of renal fibrosis

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Published in 2024 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23818

Abstract: Renal fibrosis (RF) is a typical pathological presentation of end‐stage chronic kidney disease (CKD) and autosomal dominant polycystic kidney disease (ADPKD). However, the precise regulatory mechanisms governing this re‐expression process remain unclear. Differentially expressed microRNAs… read more here.

Keywords: fibrosis; renal fibrosis; progression; mir 542 ... See more keywords

MiR-542-3p exerts tumor suppressive functions in non-small cell lung cancer cells by upregulating FTSJ2.

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Published in 2017 at "Life sciences"

DOI: 10.1016/j.lfs.2017.08.018

Abstract: AIMS Up-regulation or down-regulation of microRNAs (miRNAs) has been found in non-small cell lung cancer (NSCLC). However, the role and mechanism of regulation of miR-542-3p in NSCLC is still unclear. This study aimed at investigating… read more here.

Keywords: ftsj2; mir 542; non small; cancer ... See more keywords

CircRBM33 downregulation inhibits hypoxia-induced glycolysis and promotes apoptosis of breast cancer cells via a microRNA-542-3p/HIF-1α axis

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Published in 2022 at "Cell Death Discovery"

DOI: 10.1038/s41420-022-00860-6

Abstract: Many circRNAs are involved in the carcinogenesis of breast cancer (BCa) through the transcription of microRNAs (miRNAs) and mRNAs. This study investigated circRBM33 regulation of the miR-542-3p/hypoxia-inducible factor-1α (HIF-1α) axis in BCa. BCa clinical tissue… read more here.

Keywords: mir 542; 542 hif; glycolysis; bca cells ... See more keywords

Erratum: Loss of miR-542-3p enhances IGFBP-1 expression in decidualizing human endometrial stromal cells

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/srep46591

Abstract: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the… read more here.

Keywords: loss mir; creative commons; 542 enhances; mir 542 ... See more keywords

Long non-coding RNA SNHG16 regulates cell behaviors through miR-542-3p/HNF4α axis via RAS/RAF/MEK/ERK signaling pathway in pediatric neuroblastoma cells

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Published in 2020 at "Bioscience Reports"

DOI: 10.1042/bsr20200723

Abstract: Abstract Neuroblastoma (NB) is an extracranial solid tumor in children with complex mechanism. Increasing reports indicated that long non-coding RNA (lncRNA) small nucleolar RNA host gene 16 (SNHG16) account for the pathogenesis of NB. Nevertheless,… read more here.

Keywords: 542 hnf4; mir 542; hnf4 axis; ras raf ... See more keywords

circSIRT2/miR‐542‐3p/VASH1 axis regulates endothelial‐to‐mesenchymal transition (EndMT) in subretinal fibrosis in age‐related macular degeneration models

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Published in 2025 at "Aging Cell"

DOI: 10.1111/acel.14443

Abstract: Neovascular age‐related macular degeneration (nAMD), characterized by choroidal neovascularization (CNV), is one of the leading causes of severe visual impairment and irreversible vision loss around the world. Subretinal fibrosis (SRF) contributes to the incomplete response… read more here.

Keywords: fibrosis; 542 vash1; circsirt2; mir 542 ... See more keywords

Quadriceps miR-542-3p and -5p are elevated in COPD and reduce function by inhibiting ribosomal and protein synthesis

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Published in 2019 at "Journal of Applied Physiology"

DOI: 10.1152/japplphysiol.00882.2018

Abstract: Reduced physical performance reduces quality of life in patients with chronic obstructive pulmonary disease (COPD). Impaired physical performance is, in part, a consequence of reduced muscle mass and function, which is accompanied by mitochondrial dysfunction.… read more here.

Keywords: physical performance; mir 542; copd; protein synthesis ... See more keywords

β-Asarone Protects PC12 Cells Against Hypoxia-Induced Injury Via Negatively Regulating RPPH1/MiR-542-3p/DEDD2 Axis

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Published in 2022 at "Cell Transplantation"

DOI: 10.1177/09636897221079336

Abstract: Hypoxic injury to the brain is very intricate under the control of biochemical reactions induced by various factors and mechanisms. Long non-coding RNAs (lncRNAs) have already been revealed to affect pathological processes in the nervous… read more here.

Keywords: hypoxia induced; mir 542; pc12 cells; rpph1 ... See more keywords

Long noncoding RNA TUG1 regulates the progression of colorectal cancer through miR-542-3p/TRIB2 axis and Wnt/β-catenin pathway

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Published in 2021 at "Diagnostic Pathology"

DOI: 10.1186/s13000-021-01101-7

Abstract: Background Colorectal cancer (CRC) is one of the third normal malignancy worldwide. Taurine-upregulated gene 1 (TUG1), a member of long noncoding RNAs (lncRNAs), has been reported to be involved in various cancers. However, the mechanism… read more here.

Keywords: tug1; 542 trib2; mir 542; crc ... See more keywords

X-chromosome-linked miR-542-5p as a key regulator of sex disparity in rats with adjuvant-induced arthritis by promoting Th17 differentiation

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Published in 2025 at "Biomarker Research"

DOI: 10.1186/s40364-025-00741-x

Abstract: Studies have indicated that X-linked microRNAs (miRNAs) play a role in the pathogenesis of rheumatoid arthritis (RA) and its gender-specific differences. However, research on specific miRNAs remains limited. This study aims to investigate the possible… read more here.

Keywords: mir 542; gender; gender differences; linked mir ... See more keywords

Silencing LncRNA CASC9 inhibits proliferation and invasion of colorectal cancer cells by MiR-542-3p/ILK

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Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0265901

Abstract: Colorectal cancer (CRC) ranks the third in cancers and the second in the reasons of cancer-related death. More evidence indicates that long non-coding RNA participates in tumor initiation and progression. It’s known that cancer susceptibility… read more here.

Keywords: long non; mir 542; crc; coding rna ... See more keywords