Dysregulation of MicroRNA‐543 expression in colorectal cancer promotes tumor migration and invasion
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22489
Abstract: MicroRNAs (miRNAs) have been proven to act as key post‐transcriptional regulators of gene expression, involved in the genesis and development of multiple tumor types. However, the expression and roles of miR‐543 in colorectal cancer (CRC)… read more here.
Keywords: expression; colorectal cancer; mir 543; migration invasion ... See more keywords
Circ_0026123 promotes cisplatin resistance and progression of ovarian cancer by upregulating RAB1A through sequestering miR-543
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001373
Abstract: Background Circular RNAs can act as critical regulators in the tumorigenesis and chemoresistance of ovarian cancer (OC). Herein, this work aimed to probe the function and mechanism of circ_0026123 in the cisplatin (DDP) resistance and… read more here.
Keywords: ovarian cancer; resistance; circ 0026123; mir 543 ... See more keywords
Exosomal miR-543 Inhibits the Proliferation of Ovarian Cancer by Targeting IGF2
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/2003739
Abstract: Objective Ovarian cancer (OvCa) is the most lethal gynaecological malignancy worldwide. We aimed to illustrate the potential function and molecular mechanism of exosomal microRNA-543 (miR-543) in the oncogenesis and development of OvCa. Methods Differentially expressed… read more here.
Keywords: mir 543; proliferation; cell; ovarian cancer ... See more keywords
circRNA TCFL5 Promote Esophageal Cancer Progression by Modulating M2 Macrophage Polarization via the miR-543-FMNL2 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/5075615
Abstract: Objective The mechanism of circRNA on M2 macrophage polarization, which contributes to esophageal cancer, remains unclear. This study is aimed at clarifying the mechanism of circRNA on esophageal cancer by regulating M2 macrophage polarization. Methods… read more here.
Keywords: esophageal cancer; mir 543; circrna tcfl5; macrophage polarization ... See more keywords
MiR-543 promotes tumorigenesis and angiogenesis in non-small cell lung cancer via modulating metastasis associated protein 1
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Medicine"
DOI: 10.1186/s10020-020-00175-1
Abstract: Objective This study is aimed to explore the role of miR-543 in non-small cell lung cancer (NSCLC), and verify whether miR-543 targets metastasis associated protein 1 (MTA1) to affect tumorigenesis and angiogenesis in NSCLC. Methods… read more here.
Keywords: tumorigenesis angiogenesis; nsclc; via modulating; mir ... See more keywords
MiRNA-543 promotes osteosarcoma cell proliferation and glycolysis by partially suppressing PRMT9 and stabilizing HIF-1α protein
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.13672
Abstract: Osteosarcoma (OS) is the most common primary bone tumor, occurring frequently in adolescents and possessing a high malignant severity. MicroRNAs play critical roles during OS development. Thus, elucidation of the involvement of specific microRNAs in… read more here.
Keywords: mirna 543; glycolysis; cell proliferation; mir 543 ... See more keywords
miR-543 promotes colorectal cancer proliferation and metastasis by targeting KLF4.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19495
Abstract: Till now, miR-543 expression has been demonstrated to be involved in the development of some cancers. However, reports about its expression and mechanism in colorectal cancer (CRC) were conflicting [1, 2]. Here, we investigated clinical… read more here.
Keywords: colorectal cancer; proliferation; metastasis; mir 543 ... See more keywords
miRNA-543 promotes cell migration and invasion by targeting SPOP in gastric cancer
Sign Up to like & getrecommendations! Published in 2018 at "OncoTargets and therapy"
DOI: 10.2147/ott.s161316
Abstract: Background/purpose Given the emerging role of microRNA (miRNA) in cancer progression, we investigated the role and mechanism of miRNA-543 (miR-543) in gastric cancer (GC). Materials and methods Real-time quantitative polymerase chain reaction was conducted to… read more here.
Keywords: cancer; cell migration; mir 543; migration invasion ... See more keywords
MiR-543 functions as tumor suppressor in ovarian cancer by targeting TWIST1.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biological regulators and homeostatic agents"
DOI: 10.23812/19-567-a
Abstract: MicroRNAs (miRNAs) have been demonstrated to have promoting or inhibiting effects on the tumorigenesis of multiple cancers, including ovarian cancer (OC), by regulating its downstream target genes. In the presented experiment, our aim was to… read more here.
Keywords: cell proliferation; ovarian cancer; proliferation invasion; mir 543 ... See more keywords
MiR-543-3p promotes locomotor function recovery after spinal cord injury by inhibiting the expression of tumor necrosis factor superfamily member 15 in rats.
Sign Up to like & getrecommendations! Published in 2019 at "European Review for Medical and Pharmacological Sciences"
DOI: 10.26355/eurrev_201904_17540
Abstract: OBJECTIVE To explore the effect of miR-543-3p on the recovery of locomotor function after spinal cord injury (SCI) by regulating tumor necrosis factor superfamily member 15 (TNFSF15) mediated inflammation and apoptosis. MATERIALS AND METHODS Macrophages… read more here.
Keywords: mir 543; tumor necrosis; locomotor function; factor ... See more keywords
MiR-543-5p inhibits inflammation and promotes nerve regeneration through inactivation of the NF-κB in rats after spinal cord injury.
Sign Up to like & getrecommendations! Published in 2019 at "European Review for Medical and Pharmacological Sciences"
DOI: 10.26355/eurrev_201908_18626
Abstract: OBJECTIVE The aim is to determine the efficacy and specific mechanism of microRNA-543-5p (miR-543-5p) on spinal cord injury (SCI). MATERIALS AND METHODS The model of spinal cord injury was established in 6-week-old rats. Firstly, quantitative… read more here.
Keywords: cord injury; mir 543; spinal cord; nerve regeneration ... See more keywords