Maintenance of stemness by miR-589-5p in hepatocellular carcinoma cells promotes chemoresistance via STAT3 signaling.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.11.031
Abstract: The strength and duration of STAT3 signaling are tightly controlled by multiple negative feedback mechanisms under physical conditions. However, how these serial feedback loops are simultaneously disrupted in cancers, leading to constitutive activation of STAT3… read more here.
Keywords: hepatocellular carcinoma; hcc; chemoresistance; mir 589 ... See more keywords
miR-589-3p promoted osteogenic differentiation of periodontal ligament stem cells through targeting ATF1
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Orthopaedic Surgery and Research"
DOI: 10.1186/s13018-022-03000-z
Abstract: Background An increasing number of studies have shown that dysregulated miR-589-3p is associated with multiple diseases. However, the role of miR-589-3p in osteogenic differentiation of periodontal ligament stem cells (PDLSCs) remains unknown. This study aimed… read more here.
Keywords: mir 589; expression; osteogenic differentiation; pdlscs ... See more keywords
LncRNA KCNQ1OT1 promotes the apoptosis and inflammatory response of microglia by regulating the miR-589-5p/NPTN axis after spinal cord injury.
Sign Up to like & getrecommendations! Published in 2022 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765202220210188
Abstract: Spinal cord injury (SCI) is a devastating traumatic condition accompanied with excessive inflammatory response and apoptosis of microglia. Long noncoding RNAs (lncRNAs) have been confirmed to be key regulators of cell inflammatory response. Nevertheless, the… read more here.
Keywords: kcnq1ot1; inflammatory response; mir 589; spinal cord ... See more keywords