MicroRNA-596 is epigenetically inactivated and suppresses prostatic cancer cell growth and migration via regulating Wnt/β-catenin signaling
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-020-02536-y
Abstract: Objectives Although studies have reported that miR-596 extensively participates in multiple cancer progression, the biological mechanisms and effects of miR-596 in prostatic cancer remain unclear. The literature is aimed to reveal the function and possible… read more here.
Keywords: prostatic cancer; cell growth; migration; cancer ... See more keywords
Exosomal circPRRX1 functions as a ceRNA for miR-596 to promote the proliferation, migration, invasion, and reduce radiation sensitivity of gastric cancer cells via the upregulation of NF-κB activating protein
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001358
Abstract: Exosomes, which are small extracellular vesicles, have been unveiled to carry circular RNAs (circRNAs). CircRNA paired-related homeobox 1 (circPRRX1) can be transferred by exosomes derived from gastric cancer cells. Here, we investigated the activity and… read more here.
Keywords: radiation sensitivity; mir 596; exosomal circprrx1; gastric cancer ... See more keywords
High-Throughput Identification of miR-596 Inducing p53-Mediated Apoptosis in HeLa and HCT116 Cells Using Cell Microarray
Sign Up to like & getrecommendations! Published in 2017 at "SLAS Technology"
DOI: 10.1177/2472630317720870
Abstract: miRNAs play a key role in the regulation of gene networks in mammalian cells. However, little is known about their roles and functions in the apoptosis pathway. Here, we conducted a whole-genome miRNA screening for… read more here.
Keywords: identification mir; apoptosis; throughput identification; mir 596 ... See more keywords
RHPN1-AS1 drives the progression of hepatocellular carcinoma via regulating miR-596/IGF2BP2 axis.
Sign Up to like & getrecommendations! Published in 2019 at "Current pharmaceutical design"
DOI: 10.2174/1381612825666191105104549
Abstract: BACKGROUND Hepatocellular carcinoma (HCC) is one of the most deadly cancer worldwide, and its incidence is especially in China. Multiple long non-coding RNAs (lncRNAs) have been recently identified as crucial oncogenic factors or tumor suppressors.… read more here.
Keywords: hcc; rhpn1; rhpn1 as1; expression ... See more keywords
MicroRNA-596 acts as a tumor suppressor in gastric cancer and is upregulated by promotor demethylation
Sign Up to like & getrecommendations! Published in 2019 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v25.i10.1224
Abstract: BACKGROUND In the present study, we investigated a suppressive role of microRNA-596 (miR-596) in gastric cancer (GC). Moreover, the downregulation of miR-596 in GC cell lines was associated with an increase of miR-596 promoter methylation.… read more here.
Keywords: mir 596; cell lines; gastric cancer;