AntagomiR-613 protects neuronal cells from oxygen glucose deprivation/re-oxygenation via increasing SphK2 expression.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.09.049
Abstract: Oxygen glucose deprivation (OGD)/re-oxygenation (OGDR) causes damages to neuronal cells. Sphingosine kinase 2 (SphK2) expression could exert neuroprotective functions. Here, we aim to induce SphK2 expression via inhibiting the anti-SphK2 microRNA: microRNA-613 ("miR-613"). In both… read more here.
Keywords: neuronal cells; antamir 613; mir 613; expression ... See more keywords
MiR-613 functions as tumor suppressor in hepatocellular carcinoma by targeting YWHAZ.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.03.036
Abstract: MicroRNAs (miRNAs) play crucial regulators of affecting hepatocellular carcinoma (HCC) development and progression. However, the biological role and underlying molecular mechanism of miR-613 in HCC still remain well unknown. In the study, our results demonstrated… read more here.
Keywords: hepatocellular carcinoma; hcc; mir 613; expression ... See more keywords
LncRNA PSMG3AS1 promotes proliferation of non-small cell lung cancer cells by sponging miR-613 to upregulate SphK1
Sign Up to like & getrecommendations! Published in 2021 at "Cell Cycle"
DOI: 10.1080/15384101.2021.1900499
Abstract: ABSTRACT PSMG3-AS1 is a characterized oncogenic lncRNA in breast cancer, while its role in other cancers remains unclear. This study was to investigate the role and underlying mechansim of PSMG3-AS1 in non-small cell lung cancer… read more here.
Keywords: psmg3 as1; mir 613; cell; cancer ... See more keywords
Long non-coding RNA HLA-F antisense RNA 1 inhibits the maturation of microRNA-613 in polycystic ovary syndrome to promote ovarian granulosa cell proliferation and inhibit cell apoptosis
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2070965
Abstract: ABSTRACT MicroRNA-613 (miR-613) inhibits granulosa cell proliferation, suggesting its involvement in polycystic ovary syndrome (PCOS). We predicted that long non-coding RNA (lncRNA) HLA-F antisense RNA 1 (HLA-F-AS1) could interact with premature miR-613. We then explored… read more here.
Keywords: mir 613; cell; hla; rna ... See more keywords
MiR-613 Promotes Cell Death in Breast Cancer Cells by Downregulation of Nicotinamide Phosphoribosyltransferase and Reduction of NAD.
Sign Up to like & getrecommendations! Published in 2021 at "DNA and cell biology"
DOI: 10.1089/dna.2021.0330
Abstract: NAD is mainly biosynthesized by the enzymatic action of nicotinamide phosphoribosyltransferase (NAMPT) through the salvage pathway. NAD is indispensable for the proper function and metabolism of all living cells, including cancer cells. Our previous researches… read more here.
Keywords: breast cancer; mir 613; cancer cells; cancer ... See more keywords
MicroRNA-613 Enhances Nasopharyngeal Carcinoma Cell Radiosensitivity via the DNA Methyltransferase 3B/Tissue Inhibitor of Matrix Metalloproteinase-3/Signal Transducer and Activator of Transcription-1/Forkhead Box O-1 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/5699275
Abstract: Nasopharyngeal carcinoma (NPC) is a common malignancy of the nasopharynx, and radioresistant represents the main obstacle in NPC treatment. Malignant transformation of normal cells is driven by genetic and epigenetic changes, which are primarily manifested… read more here.
Keywords: nasopharyngeal carcinoma; mir 613; cell; c666 ... See more keywords
Tumor Suppressor miR-613 Alleviates Non-Small Cell Lung Cancer Cell via Repressing M2 Macrophage Polarization
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Oncology"
DOI: 10.1155/2023/2311231
Abstract: Background Non-small cell lung cancer (NSCLC) is a crucial crux of cancer-related death, and M2 macrophage polarization facilitates NSCLC development. MicroRNA-613 (miR-613) is a tumor suppressor. This research aimed to clarify the miR-613 function in… read more here.
Keywords: mir 613; cell; macrophage polarization; tumor suppressor ... See more keywords
miR-613 suppresses renal cell carcinoma proliferation, invasion and migration by regulating the AXL/AKT pathway
Sign Up to like & getrecommendations! Published in 2023 at "Experimental Biology and Medicine"
DOI: 10.1177/15353702231151962
Abstract: In the last few decades, microRNAs (miRNAs) are possible to effectively control and treat cancer. However, the function of miR-613 in renal cell carcinoma (RCC) is not very clear up to now. Here, the direction… read more here.
Keywords: mir 613; cell carcinoma; renal cell; proliferation ... See more keywords
Circular RNA circ_0020014 contributes to osteoarthritis progression via miR-613/ADAMTS5 axis
Sign Up to like & getrecommendations! Published in 2022 at "Bosnian Journal of Basic Medical Sciences"
DOI: 10.17305/bjbms.2021.6668
Abstract: Circular RNAs have been shown to be significant regulators in osteoarthritis (OA), whereas the functional effect of circ_0020014 in OA remains unclear. Our goal was to try and understand the underlying regulatory mechanism of circ_0020014… read more here.
Keywords: mir 613; adamts5; circ 0020014; 001 cells ... See more keywords
miR-613 Suppresses Chemoresistance and Stemness in Triple-Negative Breast Cancer by Targeting FAM83A
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Management and Research"
DOI: 10.2147/cmar.s276316
Abstract: Introduction Triple-negative breast cancer (TNBC) is the most aggressive malignancy of breast cancer, which represents about 20% of all cases. The prognosis of TNBC remains unfavorable due to the lack of targeted therapy and chemoresistance.… read more here.
Keywords: expression; mir 613; cancer; breast cancer ... See more keywords
CircRNA CircRIMS is Overexpressed in Esophageal Squamous Cell Carcinoma and Downregulate miR-613 Through Methylation to Increase Cell Proliferation
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Management and Research"
DOI: 10.2147/cmar.s282983
Abstract: Purpose CircRNA CircRIMS has been characterized as an oncogenic circRNA in gastric cancer, while its role in other cancers is unknown. This study aimed to explore the role of CircRIMS in esophageal squamous cell carcinoma… read more here.
Keywords: cell proliferation; mir 613; methylation; cell ... See more keywords