Articles with "mir 615" as a keyword



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MiR‐615‐3p inhibits the osteogenic differentiation of human lumbar ligamentum flavum cells via suppression of osteogenic regulators GDF5 and FOXO1

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Published in 2017 at "Cell Biology International"

DOI: 10.1002/cbin.10780

Abstract: Ossification of the ligamentum flavum (OLF) is a disease of heterotopic ossification in spinal ligaments. The key of the OLF pathogenesis is the differentiation of fibroblasts into osteoblasts. In this study, we explored the role… read more here.

Keywords: differentiation human; ligamentum flavum; differentiation; osteogenic differentiation ... See more keywords
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CircZNF609 is involved in the pathogenesis of focal segmental glomerulosclerosis by sponging miR-615-5p.

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Published in 2020 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2020.07.066

Abstract: As a set of distinct syndromes, focal segmental glomerulosclerosis (FSGS) is the most common cause of adult nephrotic syndrome with diverse mechanisms. We recently found that expression of the circular RNA circZNF609 is increased in… read more here.

Keywords: focal segmental; sponging mir; segmental glomerulosclerosis; circznf609 ... See more keywords
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circSETD3 regulates MAPRE1 through miR-615-5p and miR-1538 sponges to promote migration and invasion in nasopharyngeal carcinoma

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Published in 2020 at "Oncogene"

DOI: 10.1038/s41388-020-01531-5

Abstract: Circular RNAs (circRNAs) play an essential role in tumorigenesis and development. However, they have rarely been investigated in nasopharyngeal carcinoma (NPC). This study aimed to investigate the role of circRNA in the invasion and metastasis… read more here.

Keywords: invasion; mir; circsetd3; migration ... See more keywords
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LncRNA4474 inhibits renal fibrosis by regulating hepatocyte nuclear factor-1β through miR-615 modulation

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Published in 2022 at "Cell Cycle"

DOI: 10.1080/15384101.2022.2046982

Abstract: ABSTRACT Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) are involved in the development and progression of renal fibrosis. lncRNAs can regulate target messenger RNAs (mRNAs) by competitively binding to miRNAs. However, research on lncRNA–miRNA–mRNA interactions… read more here.

Keywords: lncrna4474; renal fibrosis; hnf; expression ... See more keywords
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Hydroxyacid Oxidase 2 (HAO2) Inhibits the Tumorigenicity of Hepatocellular Carcinoma and Is Negatively Regulated by miR-615-5p

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Published in 2022 at "Journal of Immunology Research"

DOI: 10.1155/2022/5003930

Abstract: Background Hepatocellular carcinoma (HCC) is the sixth most common kind of cancer worldwide and the third leading cause of cancer mortality. Although a few studies have shown that hydroxyacid oxidase 2 (HAO2) may prevent HCC… read more here.

Keywords: hepatocellular carcinoma; hao2; hcc; expression ... See more keywords
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CircRNA circ-OGDH (hsa_circ_0003340) Acts as a ceRNA to Regulate Glutamine Metabolism and Esophageal Squamous Cell Carcinoma Progression by the miR-615-5p/PDX1 Axis

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Published in 2021 at "Cancer Management and Research"

DOI: 10.2147/cmar.s290088

Abstract: Background Circular RNA hsa_circ_0003340 (circ-OGDH) has been uncovered to be involved in esophageal squamous cell carcinoma (ESCC) progression. However, the mechanism by which circ-OGDH regulates ESCC progression is unclear. Methods Expression levels of circ-OGDH, microRNA… read more here.

Keywords: circ; escc; cell; mir 615 ... See more keywords
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MiRNA-615-3p Alleviates Oxidative Stress Injury of Human Cardiomyocytes Via PI3K/Akt Signaling by Targeting MEF2A

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Published in 2022 at "Anatolian Journal of Cardiology"

DOI: 10.5152/anatoljcardiol.2021.901

Abstract: Background Myocardial infarction, a coronary heart disease, is a serious hazard to human health. Cardiomyocyte oxidative stress and apoptosis have been considered as the main causes of myocardial infarction. Here, we aimed to investigate the… read more here.

Keywords: apoptosis; mef2a; oxidative stress; human cardiomyocytes ... See more keywords