Tumor-derived exosomal miR-619-5p promotes tumor angiogenesis and metastasis through the inhibition of RCAN1.4.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.01.023
Abstract: Tumor-derived exosomes (TEXs) contain enriched miRNAs that act as novel non-invasive biomarkers for cancer diagnosis and play a role in cancer progression. We investigated the exosomal miRNAs that affect cancer progression in non-small cell lung… read more here.
Keywords: rcan1; angiogenesis; metastasis; mir 619 ... See more keywords
The Binding Sites of miR-619-5p in the mRNAs of Human and Orthologous Genes
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DOI: 10.1186/s12864-017-3811-6
Abstract: BackgroundNormally, one miRNA interacts with the mRNA of one gene. However, there are miRNAs that can bind to many mRNAs, and one mRNA can be the target of many miRNAs. This significantly complicates the study… read more here.
Keywords: sites mir; 619 binding; binding sites; mrnas human ... See more keywords
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes
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DOI: 10.1186/s12943-020-01237-y
Abstract: Background Pancreatic cancer is one of the most lethal malignancies and has an extremely poor diagnosis and prognosis. The development of resistance to gemcitabine is still a major challenge. The long noncoding RNA PVT1 was… read more here.
Keywords: microscopy; gemcitabine; pvt1; pancreatic cancer ... See more keywords
Identification of hsa-miR-619-5p and hsa-miR-4454 in plasma-derived exosomes as a potential biomarker for lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1138230
Abstract: Introduction: Lung cancer has long been at the forefront of all cancers in terms of incidence and mortality. Lung adenocarcinoma is the most common type of lung cancer, accounting for 40% of all lung cancer… read more here.
Keywords: mir 4454; lung adenocarcinoma; hsa; hsa mir ... See more keywords