Upregulated circular RNA circ_0007534 indicates an unfavorable prognosis in pancreatic ductal adenocarcinoma and regulates cell proliferation, apoptosis, and invasion by sponging miR‐625 and miR‐892b
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27658
Abstract: Circular RNAs (circRNAs) have been regarded as critical regulators of human diseases and biological markers in some types of malignancies, including pancreatic ductal adenocarcinoma (PDAC). Recently, circ_0007534 has been identified as a novel cancer‐related circRNA.… read more here.
Keywords: mir 625; cell proliferation; circ; mir 892b ... See more keywords
MicroRNA-625 inhibits cell invasion and epithelial–mesenchymal transition by targeting SOX4 in laryngeal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20181882
Abstract: Introduction: Laryngeal squamous cell carcinoma (LSCC) is a highly aggressive malignant cancer, but the molecular mechanisms underlying its development and progression remain largely elusive. The purpose of the present study is to investigate the expression… read more here.
Keywords: laryngeal squamous; invasion; mir 625; lscc ... See more keywords
A novel molecular mechanism mediated by circCCDC134 regulates non-small cell lung cancer progression.
Sign Up to like & getrecommendations! Published in 2023 at "Thoracic cancer"
DOI: 10.1111/1759-7714.14942
Abstract: BACKGROUND Circular RNA (circRNA) plays a crucial role in non-small cell lung cancer (NSCLC) progression. However, the role of circCCDC134 in NSCLC is still largely unknown. METHODS Quantitative real-time PCR was utilized for measuring circCCDC134,… read more here.
Keywords: mir 625; cell; non small; circccdc134 ... See more keywords
CircLASP1 silence strengthens the therapeutic effects of MK‐2206 on nasopharyngeal cancer through upregulating miR‐625
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DOI: 10.1111/cas.15725
Abstract: Therapeutic effects of MK‐2206 are largely limited due to the complexity of the pathogenesis of nasopharyngeal cancer (NPC). Here, we aimed to investigate whether and how circLASP1 is involved in the therapeutic effects of MK‐2206… read more here.
Keywords: mir 625; therapeutic effects; circlasp1; effects 2206 ... See more keywords
LINC00958 Inhibits Autophagy of Bladder Cancer Cells via Sponge Adsorption of miR-625-5p to Promote Tumor Angiogenesis and Oxidative Stress
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DOI: 10.1155/2022/2435114
Abstract: Objective This study further explored LINC00958's role in promoting tumor angiogenesis (AG) and oxidative stress (OS) development by inhibiting BC cell autophagy through sponge adsorption of miR-625-5p. Methods BC patients and healthy controls who visited… read more here.
Keywords: mir 625; linc00958 mir; linc00958; group ... See more keywords
Genome wide analysis of circulating miRNAs in growth hormone secreting pituitary neuroendocrine tumor patients’ plasma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.894317
Abstract: Background Circulating plasma miRNAs have been increasingly studied in the field of pituitary neuroendocrine tumor (PitNET) research. Our aim was to discover circulating plasma miRNAs species associated with growth hormone (GH) secreting PitNETs versus assess… read more here.
Keywords: pitnet patients; mir 625; patients plasma; pitnet ... See more keywords
Simple Isothermal and Label-Free Strategy for Colorectal Cancer Potential Biomarker miR-625-5p Detection
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DOI: 10.3390/bios13010078
Abstract: miRNA is considered a novel biomarker for cancer diagnosis and due to its low level in vivo, the development of new detection methods for it has become a research hotspot in recent years. Here, we… read more here.
Keywords: mir 625; detection; colorectal cancer; potential biomarker ... See more keywords
Large-Scale Profiling of Extracellular Vesicles Identified miR-625-5p as a Novel Biomarker of Immunotherapy Response in Advanced Non-Small-Cell Lung Cancer Patients
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DOI: 10.3390/cancers14102435
Abstract: Simple Summary Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of advanced non-small-cell lung cancer (NSCLC) leading to substantial improvement in survival time and quality of life. Nevertheless, the clinical benefit of treatment is still… read more here.
Keywords: mir 625; cancer; non small; small cell ... See more keywords
MicroRNA-625 inhibits the progression of non‑small cell lung cancer by directly targeting HOXB5 and deactivating the Wnt/β-catenin pathway.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of molecular medicine"
DOI: 10.3892/ijmm.2019.4203
Abstract: Numerous microRNAs (miRs) are dysregulated in non‑small cell lung cancer (NSCLC), serving pivotal roles in its formation and progression. miR‑625 is dysregulated in several types of human cancer, but its involvement in the formation and… read more here.
Keywords: mir 625; nsclc cells; cancer; cell ... See more keywords
The miR-625-3p/AXL axis induces non-T790M acquired resistance to EGFR-TKI via activation of the TGF-β/Smad pathway and EMT in EGFR-mutant non-small cell lung cancer
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DOI: 10.3892/or.2020.7579
Abstract: Gefitinib is currently the preferred treatment for non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR)-activating mutation. However, some patients gradually develop acquired resistance after receiving treatment. In addition to secondary T790M… read more here.
Keywords: egfr; mir 625; acquired resistance; non small ... See more keywords