Articles with "mir 638" as a keyword



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Decreased levels of serum exosomal miR‐638 predict poor prognosis in hepatocellular carcinoma

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Published in 2018 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.26650

Abstract: Currently available studies have implicated that exosome‐delivered microRNAs (miRNAs) play crucial roles in human cancer. However, the association of serum exosomal miR‐638 and hepatocellular carcinoma (HCC) remains largely unknown. We aim to investigate the expression… read more here.

Keywords: hcc; serum exosomal; exosomal mir; mir 638 ... See more keywords

Resveratrol prevented experimental pulmonary vascular remodeling via miR-638 regulating NR4A3/cyclin D1 pathway.

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Published in 2020 at "Microvascular research"

DOI: 10.1016/j.mvr.2020.103988

Abstract: OBJECTIVE Resveratrol has shown benefit for pulmonary hypertension improvement. Our previous reports showed NR4A3/cyclin D1 pathway promoted pulmonary arterial smooth muscle cells (PASMCs) proliferation. This study tried to explore the mechanism underlying this process, focusing… read more here.

Keywords: resveratrol; mir 638; pulmonary vascular; vascular remodeling ... See more keywords
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Serum exosomal miR‐638 is a prognostic marker of HCC via downregulation of VE‐cadherin and ZO‐1 of endothelial cells

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Published in 2021 at "Cancer Science"

DOI: 10.1111/cas.14807

Abstract: Hepatocellular carcinoma (HCC) is the second leading cause of cancer‐related death. High recurrence rates after curative resection and the lack of specific biomarkers for intrahepatic metastases are major clinical problems. Recently, exosomal microRNAs (miRNAs) have… read more here.

Keywords: hcc; mir 638; mir; expression ... See more keywords

Abstract 2538: MiR-638 promotes autophagy and malignant phenotypes of cancer cells via directly suppressing DACT3

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Published in 2017 at "Cancer Research"

DOI: 10.1158/1538-7445.am2017-2538

Abstract: Dyregulation of autophagy is implicated in human cancers and the mechanism details remains largely unclear. Herein we report the regulatory role of miR-638 in autophagy of esophageal squamous cell carcinoma (ESCC) and breast cancer cells.… read more here.

Keywords: mir 638; dact3; 638 promotes; cancer cells ... See more keywords
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Regulation of oxidized LDL-induced proliferation and migration in human vascular smooth muscle cells by a novel circ_0007478/miR-638/ROCK2 ceRNA network

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Published in 2023 at "Vascular Medicine"

DOI: 10.1177/1358863x221137617

Abstract: Background: Circular RNAs (circRNAs) have been implicated in the pathogenesis of atherosclerosis (AS) and the migration and proliferation of vascular smooth muscle cells (VSMCs) under oxidized low-density lipoprotein (ox-LDL). Here, we defined the exact action… read more here.

Keywords: mir 638; rock2; proliferation; circ 0007478 ... See more keywords
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MicroRNA-638 inhibits the progression of breast cancer through targeting HOXA9 and suppressing Wnt/β-cadherin pathway

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Published in 2021 at "World Journal of Surgical Oncology"

DOI: 10.1186/s12957-021-02363-7

Abstract: Background Previous studies had shown that microRNA-638 (miR-638) exhibited different effects in malignant tumors. Moreover, the function of miR-638 has not been reported in breast cancer. Hence, we designed this research to explore the function… read more here.

Keywords: mir 638; microrna 638; wnt cadherin; breast cancer ... See more keywords
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miR-638: A Promising Cancer Biomarker with Therapeutic Potential.

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Published in 2022 at "Current molecular medicine"

DOI: 10.2174/1566524022666220405125900

Abstract: BACKGROUND There is an unmet need to improve the diagnosis of cancer with precise treatment strategies. Therefore, more powerful diagnostic, prognostic, and therapeutic biomarkers are needed to overcome tumor cells. microRNAs (miRNAs, miRs), as a… read more here.

Keywords: mir 638; promising cancer; cancer biomarker; diagnostic prognostic ... See more keywords