MiR-646 prevents proliferation and progression of human breast cancer cell lines by suppressing HDAC2 expression.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and cellular probes"
DOI: 10.1016/j.mcp.2020.101649
Abstract: BACKGROUND Breast cancer is a type of cancer with a high incidence and mortality rate worldwide. Change in epigenetic mechanisms enhances cancer cell progression. Histon deacetylase 2 (HDAC2) was found to act as a potential… read more here.
Keywords: hdac2; breast cancer; cancer; cell ... See more keywords
Down-Regulation of circCOL1A2 Suppresses the Dysfunction of Diabetes-Related Retinal Microvascular Endothelial Cells via miR-646/FGF7 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Current Eye Research"
DOI: 10.1080/02713683.2022.2110264
Abstract: Abstract Purpose Diabetic retinopathy (DR), the major complication of diabetes, is the leading cause of vision loss and blindness globally. Altered circular RNAs (circRNAs) expression has been found to be involved in DR process. Hence,… read more here.
Keywords: retinal microvascular; mir 646; fgf7; circcol1a2 ... See more keywords
CircRNA WHSC1 targets the miR‐646/NPM1 pathway to promote the development of endometrial cancer
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DOI: 10.1111/jcmm.15346
Abstract: Circular RNAs (circRNAs) play important roles in human cancer progression. Their high stability and tissue specificity make circRNAs important molecular targets for clinical diagnosis, treatment and prognosis. However, the functions and molecular mechanisms of circRNA… read more here.
Keywords: overexpression; endometrial cancer; expression; cancer ... See more keywords
Doxorubicin inhibits osteosarcoma progression by regulating circ_0000006/miR-646/ BDNF axis
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DOI: 10.1186/s13018-021-02782-y
Abstract: Background Osteosarcoma (OS) is the most common aggressive bone tumor in children and teenagers. Doxorubicin (DOX) is a chemotherapeutic drug for OS. This study aims to reveal the effects and underneath mechanism of DOX treatment… read more here.
Keywords: circ 0000006; expression; cell; mir 646 ... See more keywords
CircFLNA Acts as a Sponge of miR-646 to Facilitate the Proliferation, Metastasis, Glycolysis, and Apoptosis Inhibition of Gastric Cancer by Targeting PFKFB2 [Corrigendum]
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DOI: 10.2147/cmar.s302743
Abstract: [This corrects the article DOI: 10.2147/CMAR.S264674.]. read more here.
Keywords: sponge mir; cancer; 646 facilitate; acts sponge ... See more keywords