Statin downregulation of miR-652-3p protects endothelium from dyslipidemia by promoting ISL1 expression.
Sign Up to like & getrecommendations! Published in 2020 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2020.154226
Abstract: BACKGROUND Aberrant endothelial function is a major contributing factor in cardiovascular disease. Dyslipidemia leads to decreased nitric oxide (NO) bioavailability, an early sign of endothelial failure. Low insulin gene enhancer protein (ISL1) levels decrease healthy… read more here.
Keywords: isl1 protein; isl1 expression; dyslipidemia; mir 652 ... See more keywords
miR-652 Inhibits the Proliferation, Migration, and Invasion of Osteosarcoma Cells by Targeting HOXA9 and Regulating the PI3K/Akt Signaling Pathway
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DOI: 10.1155/2022/4809312
Abstract: Objective The aim of this study was to investigate the abnormal expression of miR-652 in osteosarcoma and its related mechanism. Materials and Methods Reverse transcription-polymerase chain reaction (RT-PCR) was used to detect the expression of… read more here.
Keywords: mir 652; hoxa9; expression; proliferation ... See more keywords
Inhibition of miR-652-3p Regulates Lipid Metabolism and Inflammatory Cytokine Secretion of Macrophages to Alleviate Atherosclerosis by Improving TP53 Expression
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DOI: 10.1155/2022/9655097
Abstract: Purpose The aim was to elucidate the regulatory function of miR-652-3p on lipid metabolism and inflammatory cytokine secretion of macrophages in atherosclerosis. Methods miR-652-3p level in atherosclerosis patients, ox-LDL-treated macrophages, and their controls were monitored… read more here.
Keywords: lipid metabolism; mir 652; tp53; atherosclerosis ... See more keywords
Mechanism of OTUD5 in non-small cell lung cancer cell proliferation, invasion, and migration
Sign Up to like & getrecommendations! Published in 2022 at "Bosnian Journal of Basic Medical Sciences"
DOI: 10.17305/bjbms.2022.7206
Abstract: Ovarian tumor protease deubiquitinase 5 (OTUD5) has been discussed as a regulator of cancer development. Herein, the present study set out to explore the molecular mechanism of OTUD5 in non-small cell lung cancer (NSCLC) cell… read more here.
Keywords: cell; cell proliferation; mir 652; proliferation invasion ... See more keywords
MiR-652-3p promotes bladder cancer migration and invasion by targeting KCNN3.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201910_19275
Abstract: OBJECTIVE Increasing evidence indicated that microRNAs (miRNAs) are crucial regulators for cancer development. Bladder cancer (BCa) is a major threat to human health. The aim of this study was to analyze the roles of miR-652-3p… read more here.
Keywords: bca; cancer; migration invasion; mir 652 ... See more keywords